iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021706

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02028704

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008464.3	ENSCPOT00000008541.2	ENSCPOP00000007609.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-73	248.4	45	375
ULD/UDP/UBQ/UBQ_Other	4.70e-11	42.4	902	964

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp........kepkgellkslqklfeelwkskkkavsprellkalkkea 81
           +Gl+Nlg+tCY+N  LQ+ +   elr++l    ++++++  +        + + ++++++lq lf+ l++s++++++p+ ++kal+   
   Q: 45   VGLTNLGATCYVNTFLQVWFLNLELRQALYL-CPSTCSDHMRgdgvheekDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG--- 129
           6*****************************9.77777776666666665577888******************************9... PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
             +++ +qqDaqEf + +++ le++l                       +++k+ + k+++++ F g++   + c++c+++s    +f+
   Q: 130  --LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPHVKNIVQQQFCGEYAYLTACNQCGRQSRLIAKFY 193
           ..78899*******************.......................46789999******************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+++g++     +l+dc+++f kee+leg+n+yyce+c++kq+a+++++l +lP +L l+L+Rf f++++++++k+n+++ f + L
   Q: 194  ELELSIQGHK-----QLTDCISEFLKEEKLEGDNRYYCENCQSKQNATRTMQLVTLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEIL 277
           **********.....9************************************************************************* PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg................... 327
           d++p+++++      ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +   +                   
   Q: 278  DMEPYMEQKGG----SYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrrpkcgkg 362
           *******9554....79**************************44555************9999998665999**************** PP
   S: 328  ....staYvlfYk 336
               ++aY+l+Y+
   Q: 363  thcsRNAYMLVYR 375
           ************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+++g+ ++s+i+l  +++
   Q: 902  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGNLGVIPESVILLKADEP 964
           344489999************************************************988775 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

RRNCKGNPNC LVGIGEHIWL GEIDENTFHN IDDPNCERRK KNSFVGLTNL GATCYVNTFL 60
QVWFLNLELR QALYLCPSTC SDHMRGDGVH EEKDYEPQTI CEHLQYLFAL LQNSNRRYID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACGAAACT GCAAAGGAAA TCCAAATTGC TTGGTTGGGA TTGGTGAGCA TATTTGGTTA 60
GGAGAAATAG ATGAGAATAC TTTTCATAAC ATTGATGATC CCAACTGTGA GAGGAGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	32.31	1.00e-76	281.00
IUUC-Aml-001357	Ailuropoda melanoleuca	95.26	0.00e+00	1926.00
IUUC-Atr-002976	Amborella trichopoda	30.97	6.00e-73	269.00
IUUC-Apl-003773	Anas platyrhynchos	86.18	0.00e+00	1669.00
IUUC-Aca-004466	Anolis carolinensis	79.45	0.00e+00	855.00
IUUC-Aly-006249	Arabidopsis lyrata	29.08	3.00e-67	250.00
IUUC-Ath-006700	Arabidopsis thaliana	31.21	1.00e-76	281.00
IUUC-Ame-011554	Astyanax mexicanus	68.34	0.00e+00	1377.00
IUUC-Bta-012573	Bos taurus	93.96	0.00e+00	1917.00
IUUC-Bdi-014149	Brachypodium distachyon	32.56	5.00e-78	286.00
IUUC-Bol-016289	Brassica oleracea	27.40	8.00e-79	288.00
IUUC-Bra-017494	Brassica rapa	32.40	3.00e-79	290.00
IUUC-Cel-018662	Caenorhabditis elegans	27.35	2.00e-27	118.00
IUUC-Cja-019991	Callithrix jacchus	93.84	0.00e+00	1927.00
IUUC-Cfa-020294	Canis familiaris	95.36	0.00e+00	1961.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	36.95	1.00e-41	166.00
IUUC-Csa-023931	Chlorocebus sabaeus	95.26	0.00e+00	1946.00
IUUC-Cho-024566	Choloepus hoffmanni	96.39	5.00e-159	555.00
IUUC-Cin-025307	Ciona intestinalis	47.53	2.00e-66	245.00
IUUC-Csv-026006	Ciona savignyi	36.75	8.00e-142	498.00
IUUC-Cne-027065	Cryptococcus neoformans	28.38	2.00e-67	251.00
IUUC-Dre-027624	Danio rerio	68.35	0.00e+00	1415.00
IUUC-Dno-029633	Dasypus novemcinctus	94.47	0.00e+00	1288.00
IUUC-Dor-030809	Dipodomys ordii	71.68	0.00e+00	1083.00
IUUC-Ete-032818	Echinops telfairi	86.96	0.00e+00	923.00
IUUC-Eca-033692	Equus caballus	95.26	0.00e+00	1945.00
IUUC-Eeu-035185	Erinaceus europaeus	74.82	0.00e+00	795.00
IUUC-Fca-035676	Felis catus	94.86	0.00e+00	1955.00
IUUC-Fal-036913	Ficedula albicollis	84.89	0.00e+00	1728.00
IUUC-Gmo-038532	Gadus morhua	64.77	0.00e+00	1312.00
IUUC-Gga-041041	Gallus gallus	85.50	0.00e+00	1728.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.41	0.00e+00	1348.00
IUUC-Gma-044136	Glycine max	29.89	1.00e-87	318.00
IUUC-Ggo-045367	Gorilla gorilla	90.44	0.00e+00	1818.00
IUUC-Hsa-046019	Homo sapiens	95.26	0.00e+00	1949.00
IUUC-Hvu-047303	Hordeum vulgare	33.40	5.00e-62	231.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	92.98	0.00e+00	1922.00
IUUC-Lch-049989	Latimeria chalumnae	74.38	0.00e+00	1545.00
IUUC-Lpe-051612	Leersia perrieri	31.91	3.00e-74	273.00
IUUC-Loc-052756	Lepisosteus oculatus	69.47	0.00e+00	1460.00
IUUC-Laf-054043	Loxodonta africana	93.56	0.00e+00	1931.00
IUUC-Mcc-054986	Macaca mulatta	93.64	0.00e+00	1928.00
IUUC-Meu-056228	Macropus eugenii	76.58	0.00e+00	856.00
IUUC-Mtr-058610	Medicago truncatula	29.73	5.00e-78	286.00
IUUC-Mga-059896	Meleagris gallopavo	84.50	0.00e+00	1697.00
IUUC-Mvi-060269	Microbotryum violaceum	36.47	1.00e-61	232.00
IUUC-Mmr-060887	Microcebus murinus	95.56	0.00e+00	1945.00
IUUC-Mdo-062506	Monodelphis domestica	90.62	0.00e+00	1863.00
IUUC-Mmu-063642	Mus musculus	90.40	0.00e+00	1883.00
IUUC-Mac-064896	Musa acuminata	30.71	5.00e-73	269.00
IUUC-Mpu-066194	Mustela putorius furo	94.96	0.00e+00	1934.00
IUUC-Mlu-067233	Myotis lucifugus	93.81	0.00e+00	1920.00
IUUC-Nle-069052	Nomascus leucogenys	94.22	0.00e+00	1935.00
IUUC-Opr-070890	Ochotona princeps	90.96	0.00e+00	1121.00
IUUC-Ont-071450	Oreochromis niloticus	64.32	0.00e+00	1298.00
IUUC-Oan-073252	Ornithorhynchus anatinus	89.06	0.00e+00	1056.00
IUUC-Ocu-073796	Oryctolagus cuniculus	94.39	0.00e+00	1732.00
IUUC-Oba-075563	Oryza barthii	31.77	2.00e-76	281.00
IUUC-Obr-076394	Oryza brachyantha	31.97	6.00e-77	282.00
IUUC-Ogl-077339	Oryza glaberrima	37.78	4.00e-36	144.00
IUUC-Ogu-079007	Oryza glumaepatula	32.43	5.00e-70	259.00
IUUC-Oin-079997	Oryza indica	31.77	1.00e-76	281.00
IUUC-Olo-080364	Oryza longistaminata	31.77	1.00e-76	281.00
IUUC-Ome-081165	Oryza meridionalis	32.44	2.00e-70	261.00
IUUC-Oni-083026	Oryza nivara	31.77	9.00e-77	281.00
IUUC-Opu-083284	Oryza punctata	33.27	2.00e-70	261.00
IUUC-Oru-084797	Oryza rufipogon	31.77	1.00e-76	281.00
IUUC-Osa-086221	Oryza sativa	37.78	4.00e-36	144.00
IUUC-Ola-086568	Oryzias latipes	65.89	0.00e+00	1356.00
IUUC-Oga-088687	Otolemur garnettii	93.23	0.00e+00	1917.00
IUUC-Oar-090345	Ovis aries	94.47	0.00e+00	1920.00
IUUC-Ptr-090734	Pan troglodytes	95.26	0.00e+00	1949.00
IUUC-Pan-091704	Papio anubis	91.76	0.00e+00	1857.00
IUUC-Psi-092937	Pelodiscus sinensis	85.37	0.00e+00	1585.00
IUUC-Ppa-095808	Physcomitrella patens	28.50	1.00e-68	254.00
IUUC-Pab-098129	Pongo abelii	95.36	0.00e+00	1950.00
IUUC-Pop-099738	Populus trichocarpa	26.69	4.00e-75	276.00
IUUC-Pca-100647	Procavia capensis	91.26	7.00e-162	564.00
IUUC-Ppe-102091	Prunus persica	29.04	2.00e-80	294.00
IUUC-Pva-102719	Pteropus vampyrus	94.46	0.00e+00	1922.00
IUUC-Rno-105363	Rattus norvegicus	91.73	0.00e+00	1900.00
IUUC-Sha-107620	Sarcophilus harrisii	87.57	0.00e+00	1816.00
IUUC-Smo-109487	Selaginella moellendorffii	27.35	2.00e-82	300.00
IUUC-Sit-110683	Setaria italica	32.46	2.00e-76	280.00
IUUC-Sly-111377	Solanum lycopersicum	28.81	2.00e-74	274.00
IUUC-Stu-111969	Solanum tuberosum	30.44	5.00e-64	238.00
IUUC-Sar-113099	Sorex araneus	93.99	0.00e+00	1703.00
IUUC-Sbi-113833	Sorghum bicolor	39.80	5.00e-54	204.00
IUUC-Ssc-115279	Sus scrofa	89.27	0.00e+00	1349.00
IUUC-Tgu-117519	Taeniopygia guttata	82.39	0.00e+00	1659.00
IUUC-Tru-117651	Takifugu rubripes	64.99	0.00e+00	1342.00
IUUC-Tsy-119201	Tarsius syrichta	92.13	0.00e+00	1788.00
IUUC-Tni-120840	Tetraodon nigroviridis	66.08	0.00e+00	1365.00
IUUC-Tca-121674	Theobroma cacao	28.25	3.00e-82	300.00
IUUC-Tae-125247	Triticum aestivum	26.38	1.00e-79	291.00
IUUC-Tur-126599	Triticum urartu	32.68	6.00e-76	279.00
IUUC-Tbe-127782	Tupaia belangeri	83.76	0.00e+00	1635.00
IUUC-Ttr-128312	Tursiops truncatus	93.75	0.00e+00	1906.00
IUUC-Vpa-130348	Vicugna pacos	94.95	0.00e+00	1936.00
IUUC-Vvi-131353	Vitis vinifera	26.13	8.00e-84	305.00
IUUC-Xtr-132172	Xenopus tropicalis	70.38	0.00e+00	1345.00
IUUC-Xma-133263	Xiphophorus maculatus	67.52	0.00e+00	1337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence