iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088499

Ensembl Protein ID

ENSOGAP00000012891.2

UniProt Accession

H0XB45; H0XB45_OTOGA

Genbank Protein ID

ENSOGAP00000012891

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03089877

Gene Name

WDR27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000014376.2	ENSOGAT00000014390.2	ENSOGAP00000012891.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-24	83.2	162	200
UBD/Beta-Prp	1.90e-43	148.8	514	811

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvll 36
           gH ++vt+++f   + ++++s s D + kvWD rtg ++
   Q: 162  GHLGPVTAVEFcpWEaDTIISVSEDRSFKVWDCRTGLVT 200
           8**********9644789*****************9876 PP

UBD/Beta-Prp

   S: 9    hksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..ghe 94
           h + ++cv++ + d+++la g +++   v+d++   + + +sgh+++v++v++s+++k+l+++++Drt++vw++++ + +  l     +
   Q: 514  HPAAVCCVQYsAGDGRWLACGLANHLSLVFDASLTGAPAVFSGHDGAVRTVCWSHNQKWLLSVAQDRTLRVWSVRQTELILLLGkdMFS 602
           6778999***99******************************************************************99999844557 PP
   S: 95   dsvlslsfspsgdklv.sGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlk 167
           + v s +f+  + +++ s ++   +r ++++t +   +               + +g d +  ++v +  + ++ +++ +rt+ ++dl+
   Q: 603  KPVQSAQFYYIDAFILlSSGSELQLRKYHIDTCKDEIKrykqkswsksvcrlsMTDGVDMTSLSAVNDFYSHVVLTAGRNRTLEVFDLN 691
           88******9955444314444455666988887777668999********88755666655555555555599**************** PP
   S: 168  tgkllrtltgghtdsvyslsfdsng..........kelvsgsldgtvklwdlqtgecvrtlnghtd..nvksvrfspnderlvsgssDg 244
            g+      ++h ++++ +  ++ +          + +++ +     klwdl+t +c r ++gh +   ++  +fsp + ++v+g++D+
   Q: 692  VGCSAAVIAEAHSRPIHQICQNKGSsfatqhsqayNLFLTSAVGDGMKLWDLRTLRCERHFEGHLNrcHPCGAAFSPCGRFVVCGAEDR 780
           ********999********94444455555567889999999999*******************862267899**************** PP
   S: 245  siriWdlrsgdllktlqlhnssvisvavlsfg 276
             +++ l s+++ + l++h ++v+sva+ +++
   Q: 781  HAYVYELGSSTFSHRLAGHTDTVTSVAF-NPS 811
           ***************************9.433 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MEQSQGSLPA NSGHAGDIVI EKFWVGSTES ASHAQLACST QLCAFPLGGN GLCIRSTKDP 60
SDQFLILQGH DQPITAVAFG NKEDPLLICS ASLDCIIVWS LQECREKVLQ GLAPRGTTVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAACAGT CCCAAGGGAG TCTCCCAGCT AACAGTGGCC ATGCAGGTGA CATTGTCATA 60
GAAAAGTTCT GGGTTGGATC CACAGAGTCC GCCTCCCATG CTCAGCTGGC CTGCAGCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	61.81	0.00e+00	838.00
IUUC-Aca-004807	Anolis carolinensis	55.18	0.00e+00	895.00
IUUC-Bta-013316	Bos taurus	63.79	0.00e+00	1029.00
IUUC-Cja-018825	Callithrix jacchus	66.24	0.00e+00	1111.00
IUUC-Cfa-020895	Canis familiaris	64.71	0.00e+00	1060.00
IUUC-Cpo-022282	Cavia porcellus	60.98	0.00e+00	998.00
IUUC-Csa-023439	Chlorocebus sabaeus	67.94	0.00e+00	1046.00
IUUC-Cho-025046	Choloepus hoffmanni	58.72	0.00e+00	691.00
IUUC-Dre-028376	Danio rerio	42.12	8.00e-165	574.00
IUUC-Dno-029649	Dasypus novemcinctus	67.64	0.00e+00	916.00
IUUC-Dor-030824	Dipodomys ordii	56.74	0.00e+00	695.00
IUUC-Eca-033270	Equus caballus	69.36	0.00e+00	1139.00
IUUC-Fca-036149	Felis catus	63.00	0.00e+00	1017.00
IUUC-Fal-037410	Ficedula albicollis	52.03	0.00e+00	682.00
IUUC-Gmo-038923	Gadus morhua	39.32	3.00e-120	426.00
IUUC-Gga-040974	Gallus gallus	50.37	0.00e+00	778.00
IUUC-Gac-042310	Gasterosteus aculeatus	37.53	8.00e-107	381.00
IUUC-Ggo-044557	Gorilla gorilla	67.72	0.00e+00	1124.00
IUUC-Hsa-046312	Homo sapiens	67.48	0.00e+00	1127.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	64.84	0.00e+00	1016.00
IUUC-Laf-054450	Loxodonta africana	67.33	0.00e+00	1022.00
IUUC-Mcc-055807	Macaca mulatta	62.85	0.00e+00	892.00
IUUC-Meu-056116	Macropus eugenii	37.40	1.00e-65	244.00
IUUC-Mga-060088	Meleagris gallopavo	51.01	0.00e+00	683.00
IUUC-Mdo-062857	Monodelphis domestica	59.30	0.00e+00	994.00
IUUC-Mmu-063220	Mus musculus	62.73	0.00e+00	874.00
IUUC-Mpu-066921	Mustela putorius furo	61.44	0.00e+00	947.00
IUUC-Mlu-067717	Myotis lucifugus	57.44	0.00e+00	734.00
IUUC-Nle-069061	Nomascus leucogenys	55.95	0.00e+00	857.00
IUUC-Opr-070612	Ochotona princeps	61.63	7.00e-86	311.00
IUUC-Ont-072187	Oreochromis niloticus	41.54	2.00e-167	582.00
IUUC-Oan-072701	Ornithorhynchus anatinus	53.40	5.00e-135	474.00
IUUC-Ocu-074602	Oryctolagus cuniculus	64.25	0.00e+00	1070.00
IUUC-Ola-086633	Oryzias latipes	37.13	1.00e-123	437.00
IUUC-Oar-089256	Ovis aries	63.40	0.00e+00	986.00
IUUC-Ptr-091545	Pan troglodytes	62.01	0.00e+00	669.00
IUUC-Pan-092299	Papio anubis	67.57	0.00e+00	1108.00
IUUC-Psi-093010	Pelodiscus sinensis	56.42	0.00e+00	911.00
IUUC-Pab-097646	Pongo abelii	59.39	0.00e+00	637.00
IUUC-Pca-100720	Procavia capensis	57.82	2.00e-145	509.00
IUUC-Pva-102808	Pteropus vampyrus	56.75	0.00e+00	848.00
IUUC-Rno-105715	Rattus norvegicus	62.87	0.00e+00	993.00
IUUC-Sha-107546	Sarcophilus harrisii	57.11	0.00e+00	967.00
IUUC-Sar-113543	Sorex araneus	51.87	0.00e+00	765.00
IUUC-Ssc-116335	Sus scrofa	73.33	4.00e-48	184.00
IUUC-Tgu-117249	Taeniopygia guttata	50.34	0.00e+00	708.00
IUUC-Tsy-119238	Tarsius syrichta	65.45	0.00e+00	852.00
IUUC-Tni-120639	Tetraodon nigroviridis	33.60	1.00e-50	193.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence