iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092423

Ensembl Protein ID

ENSPANP00000012760.1

UniProt Accession

A0A096NIG2; A0A096NIG2_PAPAN

Genbank Protein ID

ENSPANP00000012760

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01056702

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000020902.1	ENSPANT00000005565.1	ENSPANP00000012760.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-17	63.9	276	320

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           + C+vC++gge    l++C+ C ++fH aCl+++  +e p+ + w C+ C 
   Q: 276  DECAVCRDGGE----LICCDGCPRAFHLACLSPP-LREIPSGT-WRCSGCL 320
           57*********....*******************.*******6.******6 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MVEMGRPQGV GDRGRDPHAT PLQETLRLKE KEGCPQAFHA LLSWLLTQDS TVILDFWRVL 60
FKDYNLERYG RLQPILDSFP KDVDLSQSRK GRKLPTIPKA LVPPPRHPTK RKASEEPRAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCCCCAGT CCCACCCTCA ACAGCCTACA CCACCACCTG ACCCCACCAC AAGCCAAGGA 60
GATGGGCGCG GAGCTGCCCA GGTCGCCAGC ACCTCTGCCT GGGAGCTCCA CCCTCTAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0003682--F:chromatin binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	74.61	2.00e-168	585.00
IUUC-Aca-004543	Anolis carolinensis	67.74	4.00e-23	98.60
IUUC-Bgr-012025	Blumeria graminis	30.06	1.00e-08	55.80
IUUC-Bta-012988	Bos taurus	74.17	2.00e-178	619.00
IUUC-Bci-013636	Botrytis cinerea	26.36	8.00e-11	63.20
IUUC-Bdi-014663	Brachypodium distachyon	48.48	2.00e-13	72.00
IUUC-Cja-019486	Callithrix jacchus	86.10	1.00e-129	455.00
IUUC-Cfa-021069	Canis familiaris	73.43	6.00e-169	587.00
IUUC-Cpo-021649	Cavia porcellus	68.27	1.00e-150	526.00
IUUC-Csa-023960	Chlorocebus sabaeus	96.84	0.00e+00	743.00
IUUC-Dre-028583	Danio rerio	39.60	2.00e-48	186.00
IUUC-Dno-029869	Dasypus novemcinctus	64.18	7.00e-120	424.00
IUUC-Dor-030263	Dipodomys ordii	75.00	2.00e-33	135.00
IUUC-Dse-031258	Dothistroma septosporum	40.35	5.00e-09	57.00
IUUC-Ete-032778	Echinops telfairi	87.32	2.00e-33	136.00
IUUC-Eca-034328	Equus caballus	73.58	5.00e-164	570.00
IUUC-Fca-035400	Felis catus	69.41	3.00e-156	545.00
IUUC-Fal-036644	Ficedula albicollis	48.67	6.00e-59	221.00
IUUC-Ggo-045250	Gorilla gorilla	92.09	0.00e+00	723.00
IUUC-Hsa-046603	Homo sapiens	92.49	0.00e+00	723.00
IUUC-Hvu-047073	Hordeum vulgare	58.70	2.00e-13	72.00
IUUC-Itr-048977	Ictidomys tridecemlineatus	72.43	3.00e-158	551.00
IUUC-Lch-050310	Latimeria chalumnae	41.10	2.00e-85	309.00
IUUC-Lpe-051272	Leersia perrieri	44.07	1.00e-09	60.10
IUUC-Loc-052508	Lepisosteus oculatus	48.18	2.00e-67	249.00
IUUC-Laf-054028	Loxodonta africana	65.97	6.00e-149	520.00
IUUC-Mcc-054935	Macaca mulatta	96.64	0.00e+00	796.00
IUUC-Mga-059318	Meleagris gallopavo	39.80	3.00e-42	165.00
IUUC-Mmr-061557	Microcebus murinus	63.55	5.00e-141	494.00
IUUC-Mdo-062475	Monodelphis domestica	49.31	5.00e-110	391.00
IUUC-Mmu-063994	Mus musculus	69.28	0.00e+00	658.00
IUUC-Mac-065614	Musa acuminata	42.03	1.00e-11	65.10
IUUC-Mpu-066347	Mustela putorius furo	75.68	0.00e+00	652.00
IUUC-Mlu-068239	Myotis lucifugus	62.50	7.00e-96	343.00
IUUC-Nle-069544	Nomascus leucogenys	83.08	2.00e-27	115.00
IUUC-Opr-071199	Ochotona princeps	73.85	1.00e-61	230.00
IUUC-Ont-072571	Oreochromis niloticus	31.00	9.00e-30	124.00
IUUC-Oan-073739	Ornithorhynchus anatinus	52.98	7.00e-135	474.00
IUUC-Ogl-077865	Oryza glaberrima	56.52	2.00e-12	68.90
IUUC-Olo-080499	Oryza longistaminata	56.52	1.00e-12	69.30
IUUC-Opu-083209	Oryza punctata	56.52	2.00e-12	68.90
IUUC-Ola-086528	Oryzias latipes	35.05	1.00e-34	141.00
IUUC-Oga-088353	Otolemur garnettii	77.43	0.00e+00	659.00
IUUC-Oar-090065	Ovis aries	76.54	1.00e-137	482.00
IUUC-Ptr-091347	Pan troglodytes	92.49	0.00e+00	697.00
IUUC-Psi-093798	Pelodiscus sinensis	52.49	9.00e-125	440.00
IUUC-Pfo-096145	Poecilia formosa	31.27	3.00e-29	123.00
IUUC-Pab-098369	Pongo abelii	88.26	2.00e-123	435.00
IUUC-Pca-100537	Procavia capensis	71.26	2.00e-169	588.00
IUUC-Ppe-101215	Prunus persica	60.42	4.00e-14	73.60
IUUC-Pva-102639	Pteropus vampyrus	74.51	2.00e-169	588.00
IUUC-Rno-105285	Rattus norvegicus	69.61	0.00e+00	628.00
IUUC-Sha-107159	Sarcophilus harrisii	49.02	2.00e-114	406.00
IUUC-Spo-108017	Schizosaccharomyces pombe	32.31	2.00e-09	57.40
IUUC-Sit-110355	Setaria italica	47.14	1.00e-12	69.30
IUUC-Sbi-113930	Sorghum bicolor	58.33	1.00e-12	69.30
IUUC-Ssc-115773	Sus scrofa	72.55	4.00e-174	604.00
IUUC-Tgu-116922	Taeniopygia guttata	46.51	9.00e-58	216.00
IUUC-Tru-118263	Takifugu rubripes	30.59	1.00e-50	193.00
IUUC-Tsy-119270	Tarsius syrichta	68.61	5.00e-78	285.00
IUUC-Tni-120138	Tetraodon nigroviridis	29.33	9.00e-50	191.00
IUUC-Tca-121757	Theobroma cacao	57.14	1.00e-13	73.20
IUUC-Tae-124715	Triticum aestivum	58.70	2.00e-13	72.00
IUUC-Tur-126422	Triticum urartu	53.19	2.00e-11	65.90
IUUC-Tme-127204	Tuber melanosporum	55.32	9.00e-14	72.80
IUUC-Tbe-128077	Tupaia belangeri	69.41	2.00e-176	612.00
IUUC-Ttr-128781	Tursiops truncatus	81.52	4.00e-82	298.00
IUUC-Xma-133054	Xiphophorus maculatus	30.23	6.00e-49	188.00
IUUC-Yli-134436	Yarrowia lipolytica	26.79	5.00e-12	66.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence