iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132112

Ensembl Protein ID

ENSXETP00000040872.3

UniProt Accession

K9J8B3; K9J8B3_XENTR

Genbank Protein ID

ENSXETP00000040872

Protein Name

Rho GTPase-activating protein 10

Genbank Nucleotide ID

AAMC01023693

Gene Name

arhgap10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000018852.3	ENSXETT00000040872.3	ENSXETP00000040872.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.10e-12	44.9	736	790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k+k ++ y+ ea+++ eL+++ G v + + +++ + gWl+g  +l+g+rGl+Pen+v+
   Q: 736  KKKAKAVYPCEAEHSSELSFEVGAVFEDV-HYSREPGWLEG--TLNGRRGLIPENYVQ 790
           7899*************************.***********..8************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MGLQPLEFSD CYLDSPWLRE RIRAHEAELD RTNRFIKDLL KDGKNLIAAT KSLSNAQRKF 60
ANSLRDFKFE FIGDAETDDE RCIADASLQE FSTFLQNLEE QREIMALNVN ETLIKPLERF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACAACAGC AGCTGTAGGT CCCACATGCC GAGTATACCA GGAGTCTCCC ATCGGCATTA 60
GACTGGGGGG GGGGGTCTCT TGATACTTTT GCAGTTCTGT TTAAAGGGGA GAGAGAGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50238--RHOGAP
PS50002--SH3

Pfam

PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	70.35	0.00e+00	1117.00
IUUC-Apl-003297	Anas platyrhynchos	69.60	0.00e+00	1075.00
IUUC-Aca-005285	Anolis carolinensis	70.85	0.00e+00	1116.00
IUUC-Bta-012379	Bos taurus	70.35	0.00e+00	1075.00
IUUC-Cja-019182	Callithrix jacchus	69.35	0.00e+00	1090.00
IUUC-Cfa-021141	Canis familiaris	69.97	0.00e+00	1110.00
IUUC-Csa-023847	Chlorocebus sabaeus	67.65	0.00e+00	998.00
IUUC-Cin-025725	Ciona intestinalis	38.01	4.00e-141	495.00
IUUC-Dre-027525	Danio rerio	57.88	0.00e+00	835.00
IUUC-Dor-030308	Dipodomys ordii	64.60	0.00e+00	895.00
IUUC-Eca-033545	Equus caballus	69.35	0.00e+00	999.00
IUUC-Fca-036457	Felis catus	70.48	0.00e+00	1125.00
IUUC-Fal-036703	Ficedula albicollis	71.32	0.00e+00	1114.00
IUUC-Gga-040830	Gallus gallus	71.45	0.00e+00	1122.00
IUUC-Gac-041728	Gasterosteus aculeatus	53.28	0.00e+00	780.00
IUUC-Ggo-044569	Gorilla gorilla	67.38	0.00e+00	973.00
IUUC-Hsa-045658	Homo sapiens	68.84	0.00e+00	1083.00
IUUC-Loc-051740	Lepisosteus oculatus	59.05	0.00e+00	921.00
IUUC-Laf-053641	Loxodonta africana	69.94	0.00e+00	1075.00
IUUC-Mcc-055152	Macaca mulatta	70.51	0.00e+00	1123.00
IUUC-Mga-060152	Meleagris gallopavo	50.00	2.00e-53	201.00
IUUC-Mmr-061434	Microcebus murinus	69.76	0.00e+00	1009.00
IUUC-Mdo-062864	Monodelphis domestica	71.07	0.00e+00	1134.00
IUUC-Mmu-064061	Mus musculus	69.97	0.00e+00	1083.00
IUUC-Mlu-067375	Myotis lucifugus	67.61	0.00e+00	990.00
IUUC-Ont-071443	Oreochromis niloticus	57.41	0.00e+00	866.00
IUUC-Oan-072978	Ornithorhynchus anatinus	67.87	0.00e+00	912.00
IUUC-Ocu-074591	Oryctolagus cuniculus	64.30	0.00e+00	947.00
IUUC-Ola-087508	Oryzias latipes	62.91	0.00e+00	738.00
IUUC-Oga-088922	Otolemur garnettii	64.06	2.00e-131	461.00
IUUC-Oar-089531	Ovis aries	68.45	0.00e+00	1081.00
IUUC-Ptr-091149	Pan troglodytes	69.10	0.00e+00	1092.00
IUUC-Pan-092591	Papio anubis	69.22	0.00e+00	1102.00
IUUC-Pma-094731	Petromyzon marinus	30.56	4.00e-19	90.90
IUUC-Pfo-097265	Poecilia formosa	57.66	0.00e+00	853.00
IUUC-Pab-097780	Pongo abelii	68.59	0.00e+00	1081.00
IUUC-Rno-104991	Rattus norvegicus	69.97	0.00e+00	1083.00
IUUC-Sha-107629	Sarcophilus harrisii	66.28	0.00e+00	902.00
IUUC-Ssc-115511	Sus scrofa	54.30	5.00e-146	510.00
IUUC-Tgu-117458	Taeniopygia guttata	69.39	0.00e+00	1077.00
IUUC-Tru-117724	Takifugu rubripes	63.72	0.00e+00	727.00
IUUC-Tni-120498	Tetraodon nigroviridis	48.91	6.00e-43	167.00
IUUC-Tca-121810	Theobroma cacao	31.82	1.60e+00	26.90
IUUC-Tbe-128126	Tupaia belangeri	24.37	7.00e-06	45.80
IUUC-Ttr-129045	Tursiops truncatus	66.26	0.00e+00	952.00
IUUC-Vvi-131727	Vitis vinifera	33.33	4.20e-01	28.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence