iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120631

UUCD1 version

UUC-TeN-01136

Ensembl Protein ID

ENSTNIP00000017405.1

UniProt Accession

H3DA64; H3DA64_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000014388.1	ENSTNIT00000017623.1	ENSTNIP00000017405.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-106	356.5	698	1536

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++l+ ++  +ln++np ++ g+++k++ +l+ elw++++k+v+p +l  +++k+a++f+g
   Q: 698  TGLSNLGNTCFMNSSIQCVSNTKPLTDYFLSgRHLYELNRTNPIGMRGHMAKCYGDLVMELWSGTQKSVAPLKLRWTIAKYAPRFNG 784
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e+++++   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s r++p
   Q: 785  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSN--GRPDWevaseAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISARFDP 869
           ********************************8888..5565566777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 870  FNFLSLPLPMDSYMHLEitviklegstpvryglrlnmdekymglkkqlselcnlkpeqilltevhtsniknfpldnqkvrlsvngfl 956
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 957  cafeipvpgsptslssptltdltpiangsaggdnltdnpalipnggpntvvpcspetpvangvanghatpvqespfigyiiamhrkm 1043
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1044 mrtelyflssqknrpslfgmplivpctvhttkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvgkdgntcawc 1130
           *************************************************************************************** PP
   S: 186  ...............................................................slqdcLesftkeeelegenkyyce 209
                                                                          sl++cL++ft+eeel +++ yyc+
   Q: 1131 pwyrfcrgcviectddraslgnayiavdwdptalhlryqtsqeriveehcsveqsrraqaepiSLDSCLKAFTSEEELGEDELYYCS 1217
           *************************************************************************************** PP
   S: 210  kckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts............................ 267
           kck ++ a+kkl+l++lP++Li+hLkRf+    +++ +k +k v+fp+e +d s f++                             
   Q: 1218 KCKTHRLATKKLDLWRLPPILIVHLKRFQ--LVNGRWIKSQKIVKFPREnFDPSAFLAPrdlgqhclhsrsqsedllrvgednlssv 1302
           ****************************5..56677789********************7777777777777777777777777777 PP
   S: 268  ..............................................................peekqke.................. 274
                                                                         +     +                  
   Q: 1303 sapaglynlpkvfsvspvicvtqsqsqrgsglnlvvsptaspatsrksapslsrtsspsgspK-----Sssggrraarlrlakrsgk 1384
           777777777777777777777666666666666666666666666655555555555555550.....0555555555555555555 PP
   S: 275  ....................................................................................... 274
                                                                                                  
   Q: 1385 hwlsnskenldaaanpeadthaeaeaeaeaeaeaeagaplapgettesppsshcdvvllngdsnglsldlstdssldpdasllqhrg 1471
           555556666666666666666677777777777888888888888888888888899999999999999999999999999999999 PP
   S: 275  ....kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
               + +Y+L+a+ +HsG +++GHYv+y+kn k+kW++++Ds+++ev+ ee+     ++aY+lfY+++
   Q: 1472 ntclDAIYNLYAISCHSGIMGGGHYVTYAKNPKKKWYCYNDSSCKEVQSEEIDA---DSAYILFYEQQ 1536
           9999**************************************************...********985 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MTQQCFFREV LGDGVPPKVA EVIYTSFGGS SKGLHFNNLI VGLVLLTRGR DEEKSKYLFS 60
LFASDLGGYA AREDIEAVLR ILDGETPASL QKCFLESDKV SYERFRAWLF LNKDAFTLSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCAGC AGTGCTTCTT CAGGGAAGTG CTGGGTGATG GCGTCCCGCC TAAAGTTGCA 60
GAGGTAAGTC CCAGTTCGTG CACCAGCCGC CACCTGGTCG CCATCAGAAA AGGCTGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	72.46	0.00e+00	1966.00
IUUC-Apl-003272	Anas platyrhynchos	72.30	0.00e+00	2275.00
IUUC-Aca-005057	Anolis carolinensis	79.28	0.00e+00	2033.00
IUUC-Ame-010781	Astyanax mexicanus	82.89	0.00e+00	2190.00
IUUC-Bta-013502	Bos taurus	70.72	0.00e+00	2133.00
IUUC-Cja-018754	Callithrix jacchus	73.82	0.00e+00	2284.00
IUUC-Cfa-020526	Canis familiaris	73.73	0.00e+00	2281.00
IUUC-Cpo-021568	Cavia porcellus	75.35	0.00e+00	1941.00
IUUC-Csa-023143	Chlorocebus sabaeus	80.53	0.00e+00	2094.00
IUUC-Cho-024603	Choloepus hoffmanni	89.16	1.00e-109	392.00
IUUC-Cin-025583	Ciona intestinalis	49.08	0.00e+00	1207.00
IUUC-Csv-026344	Ciona savignyi	46.37	0.00e+00	1126.00
IUUC-Dre-028121	Danio rerio	77.13	0.00e+00	2395.00
IUUC-Dno-029911	Dasypus novemcinctus	72.43	0.00e+00	2272.00
IUUC-Dor-030608	Dipodomys ordii	57.09	1.00e-162	567.00
IUUC-Dme-032094	Drosophila melanogaster	45.26	6.00e-120	426.00
IUUC-Ete-032639	Echinops telfairi	83.85	0.00e+00	1116.00
IUUC-Eca-034253	Equus caballus	79.51	0.00e+00	2132.00
IUUC-Eeu-035084	Erinaceus europaeus	69.18	0.00e+00	1291.00
IUUC-Fca-035474	Felis catus	79.69	0.00e+00	1696.00
IUUC-Fal-036985	Ficedula albicollis	73.06	0.00e+00	2294.00
IUUC-Gmo-039568	Gadus morhua	87.51	0.00e+00	2269.00
IUUC-Gga-040509	Gallus gallus	73.13	0.00e+00	2305.00
IUUC-Gac-041757	Gasterosteus aculeatus	85.28	0.00e+00	2634.00
IUUC-Ggo-044956	Gorilla gorilla	72.91	0.00e+00	1451.00
IUUC-Hsa-046107	Homo sapiens	80.31	0.00e+00	2113.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	65.55	0.00e+00	784.00
IUUC-Lch-050681	Latimeria chalumnae	69.30	0.00e+00	2160.00
IUUC-Loc-052474	Lepisosteus oculatus	74.21	0.00e+00	2332.00
IUUC-Laf-054273	Loxodonta africana	80.06	0.00e+00	2109.00
IUUC-Mcc-054718	Macaca mulatta	80.53	0.00e+00	2115.00
IUUC-Meu-056558	Macropus eugenii	60.77	0.00e+00	1137.00
IUUC-Mga-059892	Meleagris gallopavo	73.38	0.00e+00	2284.00
IUUC-Mmr-060866	Microcebus murinus	73.00	0.00e+00	2288.00
IUUC-Mdo-062607	Monodelphis domestica	73.77	0.00e+00	2316.00
IUUC-Mmu-063797	Mus musculus	73.09	0.00e+00	2299.00
IUUC-Mpu-066121	Mustela putorius furo	73.73	0.00e+00	2302.00
IUUC-Mlu-067581	Myotis lucifugus	79.86	0.00e+00	2135.00
IUUC-Nle-069916	Nomascus leucogenys	78.29	0.00e+00	2037.00
IUUC-Opr-071073	Ochotona princeps	65.94	0.00e+00	896.00
IUUC-Ont-071310	Oreochromis niloticus	90.61	0.00e+00	2397.00
IUUC-Oan-073356	Ornithorhynchus anatinus	73.50	0.00e+00	2305.00
IUUC-Ocu-074216	Oryctolagus cuniculus	79.09	0.00e+00	2113.00
IUUC-Ola-087434	Oryzias latipes	82.05	0.00e+00	2498.00
IUUC-Oga-089034	Otolemur garnettii	79.32	0.00e+00	2078.00
IUUC-Oar-090369	Ovis aries	74.10	0.00e+00	2327.00
IUUC-Ptr-090605	Pan troglodytes	80.53	0.00e+00	2116.00
IUUC-Pan-092381	Papio anubis	80.56	0.00e+00	2114.00
IUUC-Psi-093819	Pelodiscus sinensis	73.83	0.00e+00	2350.00
IUUC-Pma-094480	Petromyzon marinus	62.93	0.00e+00	1405.00
IUUC-Pfo-096561	Poecilia formosa	88.95	0.00e+00	2284.00
IUUC-Pab-097643	Pongo abelii	80.05	0.00e+00	2062.00
IUUC-Pca-100944	Procavia capensis	67.37	0.00e+00	828.00
IUUC-Pva-102732	Pteropus vampyrus	71.59	0.00e+00	1879.00
IUUC-Rno-105113	Rattus norvegicus	72.90	0.00e+00	2282.00
IUUC-Sar-113201	Sorex araneus	69.13	0.00e+00	1091.00
IUUC-Tgu-117322	Taeniopygia guttata	73.53	0.00e+00	2320.00
IUUC-Tru-118705	Takifugu rubripes	81.78	0.00e+00	716.00
IUUC-Tsy-119433	Tarsius syrichta	69.15	0.00e+00	1140.00
IUUC-Tbe-127553	Tupaia belangeri	74.46	3.00e-158	553.00
IUUC-Ttr-128260	Tursiops truncatus	72.45	0.00e+00	2270.00
IUUC-Vpa-130479	Vicugna pacos	69.03	0.00e+00	2099.00
IUUC-Xtr-132686	Xenopus tropicalis	72.93	0.00e+00	2249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence