iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000011453.1	ENSONIT00000014424.1	ENSONIP00000014413.1
ENSONIG00000011453.1	ENSONIT00000014425.1	ENSONIP00000014414.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.70e-09	35.9	15	82
E3 activity/RING/RING	2.20e-08	34.9	19	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
           +++ Cp+   ++rdP+ lp+ +++ r+++ k   +++k+cPv+r+  +e++ + n +l++  + ++++ 
   Q: 15   QDLTCPVCQGIFRDPMLLPCTHSFCRECLVKNW-EYNKKCPVCREVCEEDKAIANRALKSACETFLKQT 82
           6789************************98753.66666**************************9986 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++C+  f+d p++lpC H f+++Cl ++w      ++++  CP+Cr
   Q: 19   CPVCQGIFRD-PMLLPCTHSFCRECLvKNW------EYNKK-CPVCR 57
           ********99.999****************......88887.****8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSDNMDEDEP LPLQQDLTCP VCQGIFRDPM LLPCTHSFCR ECLVKNWEYN KKCPVCREVC 60
EEDKAIANRA LKSACETFLK QTNKRPKTIQ PSEAVCNLHL KPLELYCEKD EEPVCVECVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCCTCCAG GACCACTAGA GGGCAGTGCT TCAAAAAACA GTGAGTAGAT CTGCTTCCTG 60
TAGCACAAAC ACGGAAAAGG AGTTGGGGAG GGAGAAGTTG TTGAACTTCG TCAACGCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR003613--Ubox_domain
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
SM00504--Ubox

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011449	Astyanax mexicanus	54.82	6.00e-158	550.00
IUUC-Dre-027778	Danio rerio	53.05	2.00e-152	532.00
IUUC-Ola-086860	Oryzias latipes	59.35	4.00e-74	272.00
IUUC-Pfo-096713	Poecilia formosa	67.23	0.00e+00	664.00
IUUC-Tru-117587	Takifugu rubripes	55.51	8.00e-144	503.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence