iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118379

UUCD1 version

UUC-TaR-01138

Ensembl Protein ID

ENSTRUP00000021260.1

UniProt Accession

H2T9C0; H2T9C0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp12b; LOC101071205

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008490.1	ENSTRUT00000021348.1	ENSTRUP00000021260.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-96	323.8	45	378

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l     k++    + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 45   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA---YKVQ----PRRKESLLTCLADLFNSIAtqKKKVGVIPPKKFISRLRKENELFDNY 126
           6******************************...4554....45789*************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde......aeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           +qqDa+Efl++ll+++ + l++ek++++++       +l ++       ++  k+ ++++++++Fqg+l+++++cl+c+ vss++e+fl
   Q: 127  MQQDAHEFLNYLLNTIADLLQEEKSQERQQN-----GKLVQNggggvgGSDGGKETQQTWVHEIFQGTLTNETRCLNCEAVSSKDEDFL 210
           ********************55222222222.....2222225666668899999999******************************* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           dls++v++++     s+++cL+ f+++e+l++e kyyce+c++kqea+k++++kklP +L lhLkRf++  + ++ +k++ +v fpleL
   Q: 211  DLSVDVEQNT-----SITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLEL 294
           **********.....9**********************************************************************666 PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
            l  f+ts +   + ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 295  RL--FNTSGDA-TNPDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 378
           65..7777444.4469***************************.888*******************999*****************97 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QYGGLRMEIL MTVRKIASIC TMGANASALE KEIGPEQFPV NEHYFGLVNF GNTCYCNSVL 60
QALYFCRPFR EKVLAYKVQP RRKESLLTCL ADLFNSIATQ KKKVGVIPPK KFISRLRKEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAACTCTG CAGCCGCATC GGCTCTGATA ATTTACCACC GGGGTTCGGT CCAATATGGC 60
GGCTTACGGA TGGAAATACT GATGACAGTC CGAAAGATCG CCTCGATTTG TACGATGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003733	Anas platyrhynchos	89.30	0.00e+00	669.00
IUUC-Aca-005054	Anolis carolinensis	93.05	0.00e+00	691.00
IUUC-Ame-011132	Astyanax mexicanus	93.80	0.00e+00	741.00
IUUC-Dre-027548	Danio rerio	95.04	0.00e+00	741.00
IUUC-Fal-037172	Ficedula albicollis	90.37	0.00e+00	681.00
IUUC-Gga-041044	Gallus gallus	91.98	0.00e+00	693.00
IUUC-Lch-050237	Latimeria chalumnae	91.44	0.00e+00	688.00
IUUC-Loc-052559	Lepisosteus oculatus	94.12	0.00e+00	724.00
IUUC-Mga-059602	Meleagris gallopavo	92.27	0.00e+00	668.00
IUUC-Ont-072049	Oreochromis niloticus	94.39	0.00e+00	744.00
IUUC-Psi-093379	Pelodiscus sinensis	92.51	0.00e+00	696.00
IUUC-Pfo-097041	Poecilia formosa	94.43	0.00e+00	720.00
IUUC-Tgu-116825	Taeniopygia guttata	91.20	0.00e+00	689.00
IUUC-Xtr-132082	Xenopus tropicalis	93.05	0.00e+00	715.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence