iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027716

Ensembl Protein ID

ENSDARP00000099944.3

UniProt Accession

F1R8W7; F1R8W7_DANRE

Genbank Protein ID

ENSDARP00000099944

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CABZ01088284

Gene Name

RNF5; rnf5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000075606.3	ENSDART00000113368.3	ENSDARP00000099944.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	74.29	3.00e-41	165.00	IUUC-Hsa-046046

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

MEAAEQQRSS SDGAAARGAG FPGSGGGAGP GGGAEGERDR ERATFECNIC LDTARDAVIS 60
LCGHLFWEPC YFQWLETRPS RQQCPVCKAG ISRDKVIPLY GRGSSSQEDP RLQNDPRPQG 120

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Nucleotide Sequence
(Fasta)

CGCGCAGTGA ATGCGAGCGC GAGAGGATGG AGGCCGCAGA GCAGCAGCGG AGCTCGAGTG 60
ACGGCGCGGC CGCCAGAGGA GCGGGTTTCC CGGGCAGCGG AGGCGGAGCA GGTCCTGGTG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF00097--zf-C3HC4

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001417	Ailuropoda melanoleuca	73.81	4.00e-52	197.00
IUUC-Ame-011316	Astyanax mexicanus	86.99	1.00e-68	251.00
IUUC-Bta-013109	Bos taurus	73.02	1.00e-51	195.00
IUUC-Cja-019902	Callithrix jacchus	72.22	7.00e-51	192.00
IUUC-Cfa-020079	Canis familiaris	73.02	1.00e-51	195.00
IUUC-Cpo-021320	Cavia porcellus	68.38	1.00e-48	185.00
IUUC-Csa-023595	Chlorocebus sabaeus	73.02	6.00e-52	196.00
IUUC-Dor-030170	Dipodomys ordii	75.81	2.00e-52	197.00
IUUC-Eca-033642	Equus caballus	72.93	3.00e-53	200.00
IUUC-Eeu-034778	Erinaceus europaeus	75.76	6.00e-40	155.00
IUUC-Fca-036326	Felis catus	74.19	2.00e-52	198.00
IUUC-Gac-042258	Gasterosteus aculeatus	86.51	6.00e-60	223.00
IUUC-Ggo-045474	Gorilla gorilla	73.02	9.00e-52	196.00
IUUC-Hsa-046046	Homo sapiens	73.02	1.00e-51	195.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	74.40	3.00e-52	197.00
IUUC-Lch-050367	Latimeria chalumnae	75.00	2.00e-44	171.00
IUUC-Lma-053230	Leptosphaeria maculans	40.00	2.00e-07	51.60
IUUC-Laf-053395	Loxodonta africana	74.19	2.00e-51	195.00
IUUC-Mcc-054833	Macaca mulatta	73.02	6.00e-52	196.00
IUUC-Mdo-062437	Monodelphis domestica	70.45	2.00e-52	198.00
IUUC-Mmu-064159	Mus musculus	73.60	1.00e-51	196.00
IUUC-Mlu-067689	Myotis lucifugus	65.99	6.00e-53	199.00
IUUC-Nle-069705	Nomascus leucogenys	73.02	1.00e-51	195.00
IUUC-Ont-072482	Oreochromis niloticus	88.89	6.00e-62	229.00
IUUC-Ocu-074208	Oryctolagus cuniculus	73.39	9.00e-51	192.00
IUUC-Ola-086507	Oryzias latipes	80.79	2.00e-64	238.00
IUUC-Oga-088912	Otolemur garnettii	73.81	4.00e-52	197.00
IUUC-Oar-090284	Ovis aries	73.02	1.00e-51	195.00
IUUC-Ptr-090919	Pan troglodytes	71.88	1.00e-51	195.00
IUUC-Pan-092843	Papio anubis	73.02	6.00e-52	196.00
IUUC-Pfo-096818	Poecilia formosa	84.21	7.00e-62	229.00
IUUC-Pab-098244	Pongo abelii	73.02	1.00e-51	195.00
IUUC-Pca-100319	Procavia capensis	74.40	2.00e-52	198.00
IUUC-Pva-102249	Pteropus vampyrus	68.99	4.00e-48	183.00
IUUC-Pte-104163	Pyrenophora teres	44.12	5.00e-09	54.70
IUUC-Rno-106042	Rattus norvegicus	73.60	1.00e-51	196.00
IUUC-Ssc-115934	Sus scrofa	73.81	4.00e-52	197.00
IUUC-Tru-118679	Takifugu rubripes	58.06	1.00e-25	108.00
IUUC-Tsy-119615	Tarsius syrichta	75.83	2.00e-51	194.00
IUUC-Tbe-127773	Tupaia belangeri	74.60	1.00e-51	195.00
IUUC-Xtr-132608	Xenopus tropicalis	69.17	9.00e-43	166.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence