iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074531

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02006435

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000012044.2	ENSOCUT00000012042.2	ENSOCUP00000010362.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-59	195.0	105	143
UBD/Beta-Prp	5.70e-133	442.7	725	943

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht +v claf sd  +l+s + D  +t+ +WD+++g+ l
   Q: 105  HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWKKGKFL 143
           99*********999*******9999********999876 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ i vwd++t k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t 
   Q: 725  GHDDDILS-LTIHPVKDYVATGqvGRDAAIHVWDTQTLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATT 812
           45555555.999*********95569******************77899*********************77788889*********** PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p   dklv+ +  + i+ w+   g   ++       g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 813  RGHKDKIFVVKCNPHHvDKLVTVG-MKHIKFWQQAGGGFTSKrgifGSVGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDIVLLKT 898
           **************7769999987.99*****9888888887998777899999*************************..889***** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 899  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 943
           *98.*******99888..57*********************9997655 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MADRTAPSCQ LRLEWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQKFFLGH 60
NDDIISLALH PDKTLIATGQ VGKEPYICIW DSYNVQTVSI LKDVHTHGVA CLAFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATC GGACAGCTCC CAGTTGCCAG CTCCGGCTGG AGTGGGTGTA CGGGTACCGG 60
GGCCACCAGT GCCGCAACAA CCTGTACTAC ACGGCTGGCA AGGAGGTGGT TTACTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

KEGG

ocu:100346951

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	98.37	0.00e+00	3867.00
IUUC-Apl-003604	Anas platyrhynchos	93.90	0.00e+00	3691.00
IUUC-Aca-004572	Anolis carolinensis	89.86	0.00e+00	3588.00
IUUC-Ame-010713	Astyanax mexicanus	80.33	0.00e+00	3221.00
IUUC-Bta-012812	Bos taurus	97.85	0.00e+00	3850.00
IUUC-Cja-019191	Callithrix jacchus	97.37	0.00e+00	3812.00
IUUC-Cfa-020041	Canis familiaris	98.25	0.00e+00	3593.00
IUUC-Cpo-022304	Cavia porcellus	72.04	0.00e+00	2877.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.82	3.00e-101	365.00
IUUC-Csa-023689	Chlorocebus sabaeus	97.02	0.00e+00	3731.00
IUUC-Cho-025038	Choloepus hoffmanni	97.65	0.00e+00	1499.00
IUUC-Cin-025205	Ciona intestinalis	62.19	0.00e+00	2584.00
IUUC-Csv-026014	Ciona savignyi	63.65	0.00e+00	2606.00
IUUC-Dre-028772	Danio rerio	74.09	0.00e+00	3088.00
IUUC-Dno-029982	Dasypus novemcinctus	95.80	0.00e+00	3667.00
IUUC-Dor-030980	Dipodomys ordii	69.86	0.00e+00	1300.00
IUUC-Ete-032554	Echinops telfairi	71.91	0.00e+00	830.00
IUUC-Eca-034161	Equus caballus	96.53	0.00e+00	3686.00
IUUC-Fca-036307	Felis catus	98.37	0.00e+00	3864.00
IUUC-Fal-037332	Ficedula albicollis	92.69	0.00e+00	3614.00
IUUC-Gmo-039057	Gadus morhua	74.89	0.00e+00	2996.00
IUUC-Gga-041095	Gallus gallus	74.86	0.00e+00	2233.00
IUUC-Gac-042555	Gasterosteus aculeatus	80.25	0.00e+00	3228.00
IUUC-Ggo-045107	Gorilla gorilla	97.85	0.00e+00	3853.00
IUUC-Hsa-046482	Homo sapiens	97.91	0.00e+00	3855.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	96.43	0.00e+00	3734.00
IUUC-Lch-050306	Latimeria chalumnae	73.47	0.00e+00	2763.00
IUUC-Loc-052642	Lepisosteus oculatus	88.54	0.00e+00	3486.00
IUUC-Laf-053649	Loxodonta africana	95.71	0.00e+00	3737.00
IUUC-Mcc-055361	Macaca mulatta	98.02	0.00e+00	3385.00
IUUC-Meu-056618	Macropus eugenii	78.89	0.00e+00	1803.00
IUUC-Mga-059202	Meleagris gallopavo	92.99	0.00e+00	3573.00
IUUC-Mmr-060729	Microcebus murinus	95.61	0.00e+00	3823.00
IUUC-Mdo-062462	Monodelphis domestica	95.30	0.00e+00	3672.00
IUUC-Mmu-063865	Mus musculus	96.83	0.00e+00	3837.00
IUUC-Mpu-066724	Mustela putorius furo	98.47	0.00e+00	3870.00
IUUC-Mlu-067816	Myotis lucifugus	97.61	0.00e+00	3857.00
IUUC-Nle-069911	Nomascus leucogenys	74.63	0.00e+00	3081.00
IUUC-Opr-070213	Ochotona princeps	95.22	0.00e+00	2006.00
IUUC-Ont-071928	Oreochromis niloticus	79.89	0.00e+00	3249.00
IUUC-Oan-073563	Ornithorhynchus anatinus	95.16	0.00e+00	3759.00
IUUC-Ola-086943	Oryzias latipes	79.01	0.00e+00	3147.00
IUUC-Olu-087860	Ostreococcus lucimarinus	38.84	3.00e-117	416.00
IUUC-Oga-088665	Otolemur garnettii	96.74	0.00e+00	3699.00
IUUC-Oar-090429	Ovis aries	98.01	0.00e+00	3856.00
IUUC-Ptr-091168	Pan troglodytes	91.67	0.00e+00	3568.00
IUUC-Pan-092788	Papio anubis	97.95	0.00e+00	3070.00
IUUC-Psi-093281	Pelodiscus sinensis	92.27	0.00e+00	3652.00
IUUC-Pma-094424	Petromyzon marinus	73.19	7.00e-125	439.00
IUUC-Pfo-096073	Poecilia formosa	74.81	0.00e+00	3123.00
IUUC-Pab-098561	Pongo abelii	96.80	0.00e+00	3340.00
IUUC-Pca-100177	Procavia capensis	86.64	0.00e+00	1542.00
IUUC-Pva-102880	Pteropus vampyrus	71.44	0.00e+00	2811.00
IUUC-Rno-105002	Rattus norvegicus	96.07	0.00e+00	3822.00
IUUC-Sha-107105	Sarcophilus harrisii	92.79	0.00e+00	3551.00
IUUC-Ssc-116282	Sus scrofa	98.05	0.00e+00	3751.00
IUUC-Tgu-116807	Taeniopygia guttata	93.82	0.00e+00	3679.00
IUUC-Tru-118040	Takifugu rubripes	78.88	0.00e+00	3174.00
IUUC-Tsy-118941	Tarsius syrichta	64.73	0.00e+00	2241.00
IUUC-Tni-120118	Tetraodon nigroviridis	76.40	0.00e+00	3151.00
IUUC-Ttr-129138	Tursiops truncatus	71.16	0.00e+00	2808.00
IUUC-Vpa-130083	Vicugna pacos	70.88	0.00e+00	2721.00
IUUC-Xtr-131835	Xenopus tropicalis	73.90	0.00e+00	3106.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence