iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-049067

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01062752

Gene Name

Cul3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000015369.2	ENSSTOT00000015379.2	ENSSTOP00000013774.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.00e-130	435.8	1	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 276  leshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspEllAryiDqlLrkss 364
           ++s+++eqgka++++e + k+p++y++ ll+lk++++++++e+Fnnd+ F ++++ +fe+f+n n     ++spE+l+ +iD++L+k++
   Q: 1    MSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLN-----SRSPEYLSLFIDDKLKKGV 84
           689**************************************************************.....******************* PP
   S: 365  kglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFke 453
           kglte+e+e++ldk++++f++++ekdvFe+yYk+hLa+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf+d+++S++++++F++
   Q: 85   KGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQ 173
           ***************************************************************************************** PP
   S: 454  ekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkael............... 526
           + ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P+  ++++e+f++fYl khsgR+L++qh++g+a+l+a++               
   Q: 174  HLQATGVSlGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFygpvkkedgsevgvg 262
           ******99889*************************************************************************99999 PP
   S: 527  .......kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepeskeieeedlfsvNqef 604
                  +++k++lqVstfQm++L++fnn+ek+++ee++++t++pe+eL r+lqsL+++k  ++vl+kep+skeie++++f+vN++f
   Q: 263  gaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKptQRVLTKEPKSKEIENGHIFTVNDQF 349
           9998888888***************************************************************************99 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSSYLREQGK ALVSEEGEGK NPVDYIQGLL DLKSRFDRFL QESFNNDRLF KQTIAGDFEY 60
FLNLNSRSPE YLSLFIDDKL KKGVKGLTEQ EVETILDKAM VLFRFMQEKD VFERYYKQHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACAGATGA CCATGGATGA AAAATACGTA AACAGCATTT GGGACCTTCT GAAAAATGCA 60
ATTCAAGAAA TCCAGCGTAA GAATAACAGT GGTCTTAGTT TTGAGGAGCT CTATAGAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002278	Ailuropoda melanoleuca	99.12	0.00e+00	937.00
IUUC-Apl-004172	Anas platyrhynchos	99.78	0.00e+00	939.00
IUUC-Aca-004309	Anolis carolinensis	99.78	0.00e+00	940.00
IUUC-Acl-008317	Aspergillus clavatus	42.34	1.00e-97	350.00
IUUC-Aor-010207	Aspergillus oryzae	42.83	2.00e-101	363.00
IUUC-Ate-010305	Aspergillus terreus	42.60	8.00e-99	354.00
IUUC-Ame-011805	Astyanax mexicanus	96.68	0.00e+00	915.00
IUUC-Bta-013445	Bos taurus	100.00	0.00e+00	942.00
IUUC-Cel-018641	Caenorhabditis elegans	50.00	8.00e-124	437.00
IUUC-Cja-019175	Callithrix jacchus	99.78	0.00e+00	939.00
IUUC-Cfa-020905	Canis familiaris	100.00	0.00e+00	942.00
IUUC-Cpo-021293	Cavia porcellus	100.00	0.00e+00	942.00
IUUC-Cre-022776	Chlamydomonas reinhardtii	54.17	2.00e-141	496.00
IUUC-Csa-023800	Chlorocebus sabaeus	99.78	0.00e+00	938.00
IUUC-Cho-024839	Choloepus hoffmanni	98.45	0.00e+00	909.00
IUUC-Cin-025201	Ciona intestinalis	71.46	2.00e-167	582.00
IUUC-Csv-026107	Ciona savignyi	71.81	0.00e+00	682.00
IUUC-Cgl-026630	Colletotrichum gloeosporioides	42.76	9.00e-83	301.00
IUUC-Dre-028488	Danio rerio	96.90	0.00e+00	916.00
IUUC-Dno-029784	Dasypus novemcinctus	100.00	0.00e+00	942.00
IUUC-Dor-030682	Dipodomys ordii	89.16	0.00e+00	826.00
IUUC-Dme-032112	Drosophila melanogaster	70.00	0.00e+00	664.00
IUUC-Ete-032347	Echinops telfairi	99.76	0.00e+00	880.00
IUUC-Eca-033560	Equus caballus	99.78	0.00e+00	940.00
IUUC-Eeu-034502	Erinaceus europaeus	97.12	0.00e+00	908.00
IUUC-Fca-035544	Felis catus	100.00	0.00e+00	941.00
IUUC-Fal-036751	Ficedula albicollis	100.00	0.00e+00	942.00
IUUC-Gmo-038830	Gadus morhua	96.90	0.00e+00	919.00
IUUC-Ggr-039999	Gaeumannomyces graminis	39.65	2.00e-85	310.00
IUUC-Gga-040329	Gallus gallus	99.78	0.00e+00	941.00
IUUC-Gac-041510	Gasterosteus aculeatus	96.28	0.00e+00	917.00
IUUC-Ggo-044903	Gorilla gorilla	99.78	0.00e+00	938.00
IUUC-Hsa-046000	Homo sapiens	99.78	0.00e+00	938.00
IUUC-Lch-050458	Latimeria chalumnae	99.12	0.00e+00	936.00
IUUC-Loc-052186	Lepisosteus oculatus	98.89	0.00e+00	938.00
IUUC-Lma-053030	Leptosphaeria maculans	44.99	9.00e-100	357.00
IUUC-Laf-053684	Loxodonta africana	100.00	0.00e+00	941.00
IUUC-Mcc-055770	Macaca mulatta	99.78	0.00e+00	938.00
IUUC-Meu-056852	Macropus eugenii	100.00	0.00e+00	763.00
IUUC-Mga-060076	Meleagris gallopavo	97.12	0.00e+00	909.00
IUUC-Mvi-060470	Microbotryum violaceum	42.20	3.00e-94	339.00
IUUC-Mmr-060976	Microcebus murinus	100.00	0.00e+00	942.00
IUUC-Mdo-062741	Monodelphis domestica	100.00	0.00e+00	942.00
IUUC-Mmu-063905	Mus musculus	99.56	0.00e+00	938.00
IUUC-Mpu-066356	Mustela putorius furo	100.00	0.00e+00	941.00
IUUC-Mlu-067768	Myotis lucifugus	99.12	0.00e+00	936.00
IUUC-Nle-069638	Nomascus leucogenys	99.78	0.00e+00	939.00
IUUC-Opr-070333	Ochotona princeps	84.84	0.00e+00	704.00
IUUC-Ont-071601	Oreochromis niloticus	98.01	0.00e+00	929.00
IUUC-Oan-073281	Ornithorhynchus anatinus	99.78	0.00e+00	939.00
IUUC-Ocu-074504	Oryctolagus cuniculus	100.00	0.00e+00	942.00
IUUC-Ola-087562	Oryzias latipes	97.35	0.00e+00	923.00
IUUC-Oga-088833	Otolemur garnettii	100.00	0.00e+00	941.00
IUUC-Oar-089958	Ovis aries	100.00	0.00e+00	941.00
IUUC-Ptr-091013	Pan troglodytes	99.78	0.00e+00	938.00
IUUC-Pan-091796	Papio anubis	98.90	0.00e+00	933.00
IUUC-Psi-093564	Pelodiscus sinensis	97.12	0.00e+00	906.00
IUUC-Pno-094939	Phaeosphaeria nodorum	45.29	2.00e-100	359.00
IUUC-Pfo-097498	Poecilia formosa	90.95	0.00e+00	909.00
IUUC-Pab-098164	Pongo abelii	99.78	0.00e+00	938.00
IUUC-Pca-100702	Procavia capensis	96.71	0.00e+00	840.00
IUUC-Pva-103129	Pteropus vampyrus	99.78	0.00e+00	942.00
IUUC-Pte-104325	Pyrenophora teres	44.80	6.00e-92	332.00
IUUC-Pyt-104746	Pyrenophora triticirepentis	41.95	2.00e-88	320.00
IUUC-Rno-105935	Rattus norvegicus	99.78	0.00e+00	939.00
IUUC-Sha-106569	Sarcophilus harrisii	99.78	0.00e+00	940.00
IUUC-Sar-113144	Sorex araneus	100.00	1.00e-154	539.00
IUUC-Ssc-116053	Sus scrofa	99.78	0.00e+00	940.00
IUUC-Tgu-116523	Taeniopygia guttata	100.00	0.00e+00	941.00
IUUC-Tru-118189	Takifugu rubripes	90.93	0.00e+00	835.00
IUUC-Tsy-118962	Tarsius syrichta	89.53	0.00e+00	809.00
IUUC-Tni-120614	Tetraodon nigroviridis	61.89	1.00e-168	586.00
IUUC-Tbe-127427	Tupaia belangeri	83.86	0.00e+00	681.00
IUUC-Ttr-128662	Tursiops truncatus	100.00	0.00e+00	938.00
IUUC-Vpa-130809	Vicugna pacos	99.35	0.00e+00	647.00
IUUC-Xtr-131887	Xenopus tropicalis	98.24	0.00e+00	926.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence