iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094331

UUCD1 version

UUC-PeM-00535

Ensembl Protein ID

ENSPMAP00000000894.1

UniProt Accession

S4R6R4; S4R6R4_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000000806.1	ENSPMAT00000000898.1	ENSPMAP00000000894.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.70e-82	274.4	338	944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L++++++++++l+   + ++++    p ++ll+ l++l+++    + + k+   +++++a+++ ae+fsgy
   Q: 338  QGFSNLGNTCYMNAILQSLFALHSFTSDMLR---QGIPWN--RVPPNSLLRRLAHLLSKKDvcTMDYKKELLKRVKTAISASAERFSGY 421
           69*****************************...*****9..579************998777889999999***************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +q+Da+Efl+++ldql+e++ ++ nk++  e ++ +s ++++ ++  ++ +++++  ++++++ ++i+c  c++v +++e+f+dls+++
   Q: 422  AQNDAHEFLSQCLDQLKEDV-ERLNKKWRLEPGQGESPKPSQTDSASDMPYTCPVAANMEFEVLHTITCRVCGEVVKKKEQFNDLSIDL 509
           ********************.55999999999********************************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           p+k++    s+qd+L+ f ++e +e    y cekc++ ++a+ ++k+ klP+vLilhLkR+sf+ +  +++k+ ++v +pl L+l+ +c
   Q: 510  PRKKSDTAWSIQDSLDLFLRAEDVE----YACEKCES-RNATVTHKFIKLPRVLILHLKRYSFDVQLAVNNKVGQQVIIPLYLTLQAHC 593
           ************************9....******86.55************************************************* PP
   S: 266  ts....................................................................................... 267
           ++                                                                                       
   Q: 594  VEgtrsalslrsskhthgnmqplrssqsmnapstssnrkrytfkprvlsisesdtdedqlkralnlskqvreardntqvnedllmqmcd 682
           **999999999999999999999999999999999999999999999999999988888888888888888888888888888888888 PP
   S: 268  ........................................................................................p 268
                                                                                                   +
   Q: 683  qeptnsspdtgfcdevdfpdvaevqevesepcsevtahveepvyssiivptenweeddipvwskmdigpkkeedyagkkeegaekneqK 771
           88888888888888888888887777777777777777777777777777777777777777777777777777776666666555550 PP
   S: 269  eekqke................................................................................... 274
                                                                                                    
   Q: 772  -----Asgdedkenrtpaepepdwmdqysldrereerelqealaqslrdqeareqreedelkratelslqefqhslaevmgsdedsgne 855
           .....055555555566666666666666666666666666666777777777777777788888888888888888888888888888 PP
   S: 275  ........................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                                   +++++L++vv+H G  +s GHY+++  + k++ W+++dD+ Vt ++e++v  ++++++Y++fY +
   Q: 856  gsvelerseaealelkcnaetgdlPHSFQLLSVVSHIGsDSSAGHYISDTFDVKKQsWFTYDDTDVTRTSEATVRDTRERSGYIFFYIH 944
           999999999999999999999999****************************88888******************************86 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

SGEISVAGEI RIFTEQTGMT KWKDGVVEVV EKDTKSTLVI RFKAGGPTKT FTLTENVKSV 60
RVSDHKEHSR IMITLLDSSN ITVQYAMLGQ VQWLSQYLKD VEKNPNRGSS PLSGVLGKRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGGTGAGA TCAGCGTGGC TGGCGAGATC AGAATCTTCA CTGAACAGAC TGGAATGACC 60
AAGTGGAAGG ATGGCGTTGT CGAGGTCGTG GAGAAGGATA CTAAGTCCAC CCTTGTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil

Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001400	Ailuropoda melanoleuca	48.31	0.00e+00	745.00
IUUC-Apl-004033	Anas platyrhynchos	49.24	0.00e+00	757.00
IUUC-Aca-005370	Anolis carolinensis	46.71	0.00e+00	749.00
IUUC-Ame-011884	Astyanax mexicanus	46.23	0.00e+00	710.00
IUUC-Bta-012725	Bos taurus	48.16	0.00e+00	742.00
IUUC-Cja-019939	Callithrix jacchus	47.75	0.00e+00	737.00
IUUC-Cfa-020835	Canis familiaris	48.06	0.00e+00	766.00
IUUC-Cpo-022067	Cavia porcellus	46.26	0.00e+00	668.00
IUUC-Cre-022867	Chlamydomonas reinhardtii	31.56	9.00e-26	110.00
IUUC-Csa-023085	Chlorocebus sabaeus	47.79	0.00e+00	758.00
IUUC-Cho-024390	Choloepus hoffmanni	34.07	6.00e-47	181.00
IUUC-Cin-025496	Ciona intestinalis	34.29	2.00e-43	169.00
IUUC-Csv-025812	Ciona savignyi	36.54	5.00e-41	160.00
IUUC-Dre-028255	Danio rerio	45.88	0.00e+00	675.00
IUUC-Dno-028986	Dasypus novemcinctus	47.34	0.00e+00	733.00
IUUC-Dor-031062	Dipodomys ordii	38.59	2.00e-95	342.00
IUUC-Ete-032359	Echinops telfairi	48.72	6.00e-99	353.00
IUUC-Eca-033964	Equus caballus	47.90	0.00e+00	750.00
IUUC-Eeu-034492	Erinaceus europaeus	47.52	9.00e-102	363.00
IUUC-Fca-036359	Felis catus	48.31	0.00e+00	754.00
IUUC-Fal-037640	Ficedula albicollis	48.73	0.00e+00	734.00
IUUC-Gmo-039600	Gadus morhua	45.80	0.00e+00	695.00
IUUC-Gga-040126	Gallus gallus	48.68	0.00e+00	716.00
IUUC-Gac-041557	Gasterosteus aculeatus	44.36	0.00e+00	640.00
IUUC-Ggo-045571	Gorilla gorilla	46.33	0.00e+00	657.00
IUUC-Hsa-046043	Homo sapiens	47.90	0.00e+00	747.00
IUUC-Itr-048207	Ictidomys tridecemlineatus	47.43	0.00e+00	726.00
IUUC-Lch-050357	Latimeria chalumnae	45.33	0.00e+00	636.00
IUUC-Loc-052849	Lepisosteus oculatus	44.76	0.00e+00	668.00
IUUC-Laf-054570	Loxodonta africana	48.36	0.00e+00	722.00
IUUC-Mcc-054989	Macaca mulatta	46.41	0.00e+00	687.00
IUUC-Meu-056273	Macropus eugenii	47.60	1.00e-47	183.00
IUUC-Mga-059814	Meleagris gallopavo	47.45	0.00e+00	719.00
IUUC-Mmr-061726	Microcebus murinus	47.80	0.00e+00	756.00
IUUC-Mdo-062974	Monodelphis domestica	48.83	0.00e+00	765.00
IUUC-Mmu-064069	Mus musculus	47.80	0.00e+00	726.00
IUUC-Mpu-066008	Mustela putorius furo	46.93	0.00e+00	735.00
IUUC-Mlu-068224	Myotis lucifugus	34.58	1.00e-90	326.00
IUUC-Nle-069259	Nomascus leucogenys	47.64	0.00e+00	742.00
IUUC-Opr-070882	Ochotona princeps	64.84	3.00e-81	295.00
IUUC-Ont-072441	Oreochromis niloticus	44.34	0.00e+00	657.00
IUUC-Oan-073151	Ornithorhynchus anatinus	58.11	1.00e-87	315.00
IUUC-Ocu-074879	Oryctolagus cuniculus	47.44	0.00e+00	739.00
IUUC-Ola-087007	Oryzias latipes	44.85	0.00e+00	626.00
IUUC-Oga-088385	Otolemur garnettii	47.70	0.00e+00	760.00
IUUC-Oar-090305	Ovis aries	47.71	0.00e+00	748.00
IUUC-Ptr-091299	Pan troglodytes	47.90	0.00e+00	751.00
IUUC-Pan-091996	Papio anubis	47.67	0.00e+00	740.00
IUUC-Psi-093176	Pelodiscus sinensis	48.42	0.00e+00	742.00
IUUC-Ppa-095732	Physcomitrella patens	28.83	9.00e-28	117.00
IUUC-Pfo-096503	Poecilia formosa	44.00	0.00e+00	656.00
IUUC-Pab-098543	Pongo abelii	50.93	2.00e-118	418.00
IUUC-Pca-101099	Procavia capensis	47.61	5.00e-171	593.00
IUUC-Pva-103163	Pteropus vampyrus	46.70	2.00e-156	544.00
IUUC-Rno-105766	Rattus norvegicus	47.95	0.00e+00	737.00
IUUC-Sha-106610	Sarcophilus harrisii	47.39	0.00e+00	682.00
IUUC-Sar-113624	Sorex araneus	46.02	3.00e-56	212.00
IUUC-Ssc-116353	Sus scrofa	47.81	0.00e+00	726.00
IUUC-Tgu-116971	Taeniopygia guttata	47.07	0.00e+00	709.00
IUUC-Tru-117932	Takifugu rubripes	43.04	2.00e-111	395.00
IUUC-Tsy-119185	Tarsius syrichta	47.44	1.00e-157	548.00
IUUC-Tni-119842	Tetraodon nigroviridis	58.68	1.00e-101	362.00
IUUC-Tbe-127281	Tupaia belangeri	37.61	4.00e-67	248.00
IUUC-Ttr-128177	Tursiops truncatus	53.16	0.00e+00	629.00
IUUC-Vpa-130031	Vicugna pacos	47.54	0.00e+00	744.00
IUUC-Xtr-132949	Xenopus tropicalis	46.65	0.00e+00	734.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence