iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015083.1	ENSSHAT00000017910.1	ENSSHAP00000017764.1
ENSSHAG00000015083.1	ENSSHAT00000017911.1	ENSSHAP00000017765.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	83.00	0.00e+00	1261.00	IUUC-Hsa-046966

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

SCLDLEQCSL KVLEPEGSPS RCLLKLLGEK GCTVTELSEF LQAMEYTESV LQLLGPPGIK 60
IIVNPVSKAI LAGQHVKLCC RATGHPFVQY QWFKMKKEIP HGNSPELIFH PVLAKDSGFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTGTCTGG ACTTAGAGCA ATGTTCTCTT AAAGTACTGG AACCAGAAGG AAGTCCTAGT 60
CGTTGTTTAC TGAAACTCCT GGGTGAAAAA GGCTGCACAG TCACAGAATT GAGTGAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029030--Caspase-like_dom
IPR011029--DEATH-like_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR033540--MALT1
IPR001309--Pept_C14_p20

PROSITE

PS50208--CASPASE_P20
PS50835--IG_LIKE

Pfam

PF13895--Ig_2

SMART

SM00409--IG
SM00408--IGc2

Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0019209--F:kinase activator activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0001923--P:B-1 B cell differentiation
GO:0045087--P:innate immune response
GO:0051168--P:nuclear export
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032743--P:positive regulation of interleukin-2 production
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0050870--P:positive regulation of T cell activation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0051259--P:protein oligomerization
GO:0042981--P:regulation of apoptotic process
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0009620--P:response to fungus
GO:0002237--P:response to molecule of bacterial origin
GO:0042098--P:T cell proliferation
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003814	Anas platyrhynchos	72.64	0.00e+00	1105.00
IUUC-Aca-005192	Anolis carolinensis	64.27	0.00e+00	741.00
IUUC-Ame-010608	Astyanax mexicanus	59.62	0.00e+00	780.00
IUUC-Bta-012436	Bos taurus	79.69	0.00e+00	1211.00
IUUC-Cel-018688	Caenorhabditis elegans	26.58	8.00e-41	161.00
IUUC-Cja-018945	Callithrix jacchus	71.98	0.00e+00	1042.00
IUUC-Cfa-020245	Canis familiaris	81.39	0.00e+00	1236.00
IUUC-Cpo-022400	Cavia porcellus	79.61	0.00e+00	1202.00
IUUC-Csa-023556	Chlorocebus sabaeus	82.26	0.00e+00	1197.00
IUUC-Cho-024489	Choloepus hoffmanni	77.54	1.00e-126	446.00
IUUC-Csv-026274	Ciona savignyi	26.21	1.00e-06	47.00
IUUC-Dre-028666	Danio rerio	55.10	0.00e+00	747.00
IUUC-Dno-029397	Dasypus novemcinctus	82.65	0.00e+00	1259.00
IUUC-Ete-032600	Echinops telfairi	64.22	3.00e-120	425.00
IUUC-Eca-033475	Equus caballus	81.89	0.00e+00	1245.00
IUUC-Eeu-034788	Erinaceus europaeus	77.95	0.00e+00	1172.00
IUUC-Fca-035687	Felis catus	82.67	0.00e+00	1194.00
IUUC-Fal-037432	Ficedula albicollis	69.16	0.00e+00	1028.00
IUUC-Gmo-038533	Gadus morhua	53.55	0.00e+00	680.00
IUUC-Gga-040429	Gallus gallus	72.72	0.00e+00	1092.00
IUUC-Gac-041963	Gasterosteus aculeatus	59.55	0.00e+00	810.00
IUUC-Ggo-045328	Gorilla gorilla	82.61	0.00e+00	1242.00
IUUC-Hsa-046966	Homo sapiens	82.87	0.00e+00	1245.00
IUUC-Itr-048424	Ictidomys tridecemlineatus	83.74	0.00e+00	800.00
IUUC-Lch-049486	Latimeria chalumnae	67.78	0.00e+00	984.00
IUUC-Loc-051782	Lepisosteus oculatus	61.42	0.00e+00	872.00
IUUC-Laf-053612	Loxodonta africana	82.15	0.00e+00	1253.00
IUUC-Mcc-054811	Macaca mulatta	80.37	0.00e+00	1199.00
IUUC-Meu-056602	Macropus eugenii	96.21	5.00e-140	491.00
IUUC-Mmr-060713	Microcebus murinus	83.16	0.00e+00	1268.00
IUUC-Mdo-062385	Monodelphis domestica	90.38	0.00e+00	1380.00
IUUC-Mpu-065996	Mustela putorius furo	80.50	0.00e+00	1150.00
IUUC-Mlu-067627	Myotis lucifugus	80.00	0.00e+00	1150.00
IUUC-Nle-069583	Nomascus leucogenys	82.74	0.00e+00	1244.00
IUUC-Opr-070641	Ochotona princeps	77.70	0.00e+00	916.00
IUUC-Ont-071363	Oreochromis niloticus	60.78	0.00e+00	800.00
IUUC-Oan-073407	Ornithorhynchus anatinus	83.33	0.00e+00	753.00
IUUC-Ola-086554	Oryzias latipes	60.00	0.00e+00	760.00
IUUC-Oga-088538	Otolemur garnettii	75.76	0.00e+00	1099.00
IUUC-Oar-090012	Ovis aries	79.71	0.00e+00	1192.00
IUUC-Ptr-090677	Pan troglodytes	82.87	0.00e+00	1248.00
IUUC-Pan-092262	Papio anubis	82.74	0.00e+00	1247.00
IUUC-Psi-093186	Pelodiscus sinensis	72.60	0.00e+00	1048.00
IUUC-Pfo-097154	Poecilia formosa	59.97	0.00e+00	784.00
IUUC-Pab-098695	Pongo abelii	76.68	0.00e+00	1129.00
IUUC-Pca-100956	Procavia capensis	89.40	0.00e+00	709.00
IUUC-Pva-102917	Pteropus vampyrus	74.25	0.00e+00	743.00
IUUC-Rno-105680	Rattus norvegicus	80.27	0.00e+00	1172.00
IUUC-Sly-111729	Solanum lycopersicum	42.86	4.00e-01	30.40
IUUC-Sar-113054	Sorex araneus	76.87	0.00e+00	703.00
IUUC-Ssc-116110	Sus scrofa	78.87	0.00e+00	1166.00
IUUC-Tgu-116542	Taeniopygia guttata	74.96	0.00e+00	999.00
IUUC-Tru-118019	Takifugu rubripes	59.70	0.00e+00	774.00
IUUC-Tsy-119591	Tarsius syrichta	71.77	0.00e+00	1012.00
IUUC-Tbe-128075	Tupaia belangeri	79.17	8.00e-77	281.00
IUUC-Ttr-128309	Tursiops truncatus	75.56	0.00e+00	1093.00
IUUC-Vpa-130271	Vicugna pacos	82.75	0.00e+00	839.00
IUUC-Xtr-132554	Xenopus tropicalis	63.03	0.00e+00	891.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence