iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059296

Ensembl Protein ID

ENSMGAP00000010678.2

UniProt Accession

G1NCZ8; G1NCZ8_MELGA

Protein Name

Uncharacterized protein

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010263.2	ENSMGAT00000011539.2	ENSMGAP00000010678.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-13	50.2	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

PSASISGSDS ERRAIYDLAF KPDGTQLIVA AGSRLLVYDT SDGTLIQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY TSILCISSAS LHYALLLSVS DVRAGRRLVM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGTCGGCAT CCATCTCGGG GTCGGATTCG GAACGCCGTG CTCNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	81.66	0.00e+00	2099.00
IUUC-Apl-003504	Anas platyrhynchos	95.50	0.00e+00	1946.00
IUUC-Aca-004767	Anolis carolinensis	80.79	0.00e+00	2120.00
IUUC-Ame-011642	Astyanax mexicanus	70.73	0.00e+00	1852.00
IUUC-Bta-012969	Bos taurus	81.17	0.00e+00	2033.00
IUUC-Cel-018670	Caenorhabditis elegans	35.44	0.00e+00	835.00
IUUC-Cja-019249	Callithrix jacchus	74.58	0.00e+00	1875.00
IUUC-Cfa-020915	Canis familiaris	81.43	0.00e+00	2043.00
IUUC-Cpo-021888	Cavia porcellus	84.22	0.00e+00	1736.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	45.00	0.00e+00	931.00
IUUC-Csa-023533	Chlorocebus sabaeus	78.86	0.00e+00	1984.00
IUUC-Cin-025121	Ciona intestinalis	54.39	0.00e+00	1415.00
IUUC-Csv-026240	Ciona savignyi	56.35	0.00e+00	1419.00
IUUC-Dno-029685	Dasypus novemcinctus	88.14	0.00e+00	1770.00
IUUC-Dme-032005	Drosophila melanogaster	22.47	1.00e-07	52.40
IUUC-Ete-032682	Echinops telfairi	77.99	0.00e+00	1553.00
IUUC-Eca-033831	Equus caballus	81.25	0.00e+00	2110.00
IUUC-Eeu-034919	Erinaceus europaeus	79.27	0.00e+00	922.00
IUUC-Fca-036559	Felis catus	81.10	0.00e+00	2065.00
IUUC-Fal-037340	Ficedula albicollis	89.78	0.00e+00	1822.00
IUUC-Gga-040595	Gallus gallus	97.39	0.00e+00	1991.00
IUUC-Ggo-045356	Gorilla gorilla	79.46	0.00e+00	2012.00
IUUC-Hsa-046135	Homo sapiens	79.54	0.00e+00	2019.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	75.81	0.00e+00	1855.00
IUUC-Lch-050183	Latimeria chalumnae	83.43	0.00e+00	1178.00
IUUC-Loc-052049	Lepisosteus oculatus	84.27	0.00e+00	1731.00
IUUC-Laf-053728	Loxodonta africana	81.50	0.00e+00	2095.00
IUUC-Mcc-054971	Macaca mulatta	79.71	0.00e+00	2014.00
IUUC-Meu-056446	Macropus eugenii	78.75	0.00e+00	2031.00
IUUC-Mmr-061232	Microcebus murinus	80.75	0.00e+00	2023.00
IUUC-Mdo-062115	Monodelphis domestica	82.53	0.00e+00	2149.00
IUUC-Mmu-063664	Mus musculus	80.43	0.00e+00	2087.00
IUUC-Mpu-066136	Mustela putorius furo	77.86	0.00e+00	2021.00
IUUC-Mlu-068238	Myotis lucifugus	78.11	0.00e+00	1996.00
IUUC-Nle-069003	Nomascus leucogenys	75.44	0.00e+00	1883.00
IUUC-Ont-072080	Oreochromis niloticus	72.28	0.00e+00	1918.00
IUUC-Oan-072891	Ornithorhynchus anatinus	67.65	0.00e+00	771.00
IUUC-Ocu-074262	Oryctolagus cuniculus	79.37	0.00e+00	2003.00
IUUC-Ola-086538	Oryzias latipes	70.16	0.00e+00	1811.00
IUUC-Oga-088722	Otolemur garnettii	81.99	0.00e+00	2040.00
IUUC-Oar-089249	Ovis aries	87.46	0.00e+00	1761.00
IUUC-Ptr-090752	Pan troglodytes	78.15	0.00e+00	1969.00
IUUC-Pan-092472	Papio anubis	78.87	0.00e+00	1990.00
IUUC-Psi-093335	Pelodiscus sinensis	91.18	0.00e+00	1883.00
IUUC-Pma-094520	Petromyzon marinus	69.96	0.00e+00	1467.00
IUUC-Ppa-095600	Physcomitrella patens	43.33	1.00e-32	131.00
IUUC-Pfo-096526	Poecilia formosa	69.13	0.00e+00	1781.00
IUUC-Pab-098428	Pongo abelii	79.97	0.00e+00	973.00
IUUC-Pca-100233	Procavia capensis	64.31	0.00e+00	892.00
IUUC-Pva-103064	Pteropus vampyrus	72.23	0.00e+00	1771.00
IUUC-Rno-105764	Rattus norvegicus	80.37	0.00e+00	2067.00
IUUC-Sha-106649	Sarcophilus harrisii	83.02	0.00e+00	2165.00
IUUC-Smo-109478	Selaginella moellendorffii	40.28	0.00e+00	754.00
IUUC-Tgu-116870	Taeniopygia guttata	82.90	0.00e+00	2114.00
IUUC-Tru-118661	Takifugu rubripes	69.54	0.00e+00	1798.00
IUUC-Tsy-119640	Tarsius syrichta	80.60	6.00e-98	352.00
IUUC-Tni-120812	Tetraodon nigroviridis	68.82	0.00e+00	1788.00
IUUC-Ttr-128862	Tursiops truncatus	81.49	0.00e+00	2082.00
IUUC-Vpa-130049	Vicugna pacos	73.02	2.00e-142	499.00
IUUC-Xtr-131914	Xenopus tropicalis	75.25	0.00e+00	1928.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence