iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098778

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD repeat-containing protein 37

Genbank Nucleotide ID

ABGA01004728

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000002040.2	ENSPPYT00000002431.2	ENSPPYP00000002360.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-19	67.6	339	370
UBD/Beta-Prp	1.90e-41	142.3	252	460

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 339  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 370
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 252  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 340
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 341  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 427
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 428  RRMVCCSAWSEDHpvCNLFTCGFDRQAIGWNIN 460
           ************9888899***********986 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MPTESASCST ARQTKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTATTGCAG GAGTGACCAG GACACTACCT CCTAGAAGTA ATGCCCACAG AAAGCGCAAG 60
TTGTTCGACT GCTCGCCAAA CAAAACAGAA GCGCAAATCC CATAGCCTTT CTATACGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	91.33	0.00e+00	895.00
IUUC-Apl-003647	Anas platyrhynchos	89.70	0.00e+00	879.00
IUUC-Aca-004759	Anolis carolinensis	89.09	0.00e+00	888.00
IUUC-Ame-011103	Astyanax mexicanus	52.58	1.00e-129	456.00
IUUC-Bta-012718	Bos taurus	90.93	0.00e+00	890.00
IUUC-Cel-018499	Caenorhabditis elegans	41.59	5.00e-92	331.00
IUUC-Cja-019492	Callithrix jacchus	93.33	0.00e+00	942.00
IUUC-Cfa-020199	Canis familiaris	90.52	0.00e+00	922.00
IUUC-Cpo-022500	Cavia porcellus	85.69	0.00e+00	872.00
IUUC-Csa-023567	Chlorocebus sabaeus	94.14	0.00e+00	948.00
IUUC-Cho-025071	Choloepus hoffmanni	68.83	0.00e+00	645.00
IUUC-Cin-025460	Ciona intestinalis	44.78	8.00e-100	357.00
IUUC-Csv-026042	Ciona savignyi	45.25	9.00e-103	367.00
IUUC-Dre-028214	Danio rerio	78.95	0.00e+00	808.00
IUUC-Dno-029826	Dasypus novemcinctus	90.36	0.00e+00	759.00
IUUC-Dor-030967	Dipodomys ordii	92.24	0.00e+00	837.00
IUUC-Dme-031936	Drosophila melanogaster	48.81	5.00e-112	397.00
IUUC-Ete-032452	Echinops telfairi	89.47	0.00e+00	894.00
IUUC-Eca-033278	Equus caballus	90.73	0.00e+00	921.00
IUUC-Eeu-034592	Erinaceus europaeus	79.35	0.00e+00	772.00
IUUC-Fca-036431	Felis catus	91.15	0.00e+00	924.00
IUUC-Fal-037149	Ficedula albicollis	88.69	0.00e+00	873.00
IUUC-Gmo-038476	Gadus morhua	74.95	0.00e+00	734.00
IUUC-Gga-041099	Gallus gallus	89.49	0.00e+00	879.00
IUUC-Gac-042374	Gasterosteus aculeatus	78.60	0.00e+00	764.00
IUUC-Ggo-044683	Gorilla gorilla	86.84	0.00e+00	860.00
IUUC-Hsa-046658	Homo sapiens	94.53	0.00e+00	950.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	92.31	0.00e+00	860.00
IUUC-Lch-050571	Latimeria chalumnae	79.66	0.00e+00	817.00
IUUC-Loc-052652	Lepisosteus oculatus	78.16	0.00e+00	808.00
IUUC-Laf-053712	Loxodonta africana	90.18	0.00e+00	911.00
IUUC-Mcc-055521	Macaca mulatta	94.14	0.00e+00	948.00
IUUC-Meu-056324	Macropus eugenii	86.21	0.00e+00	843.00
IUUC-Mga-060114	Meleagris gallopavo	89.31	0.00e+00	879.00
IUUC-Mmr-061176	Microcebus murinus	92.12	0.00e+00	931.00
IUUC-Mdo-061888	Monodelphis domestica	89.92	0.00e+00	890.00
IUUC-Mmu-063977	Mus musculus	91.73	0.00e+00	934.00
IUUC-Mpu-066220	Mustela putorius furo	76.47	4.00e-161	560.00
IUUC-Mlu-068155	Myotis lucifugus	90.93	0.00e+00	926.00
IUUC-Nle-069964	Nomascus leucogenys	94.34	0.00e+00	949.00
IUUC-Opr-070925	Ochotona princeps	87.96	6.00e-134	470.00
IUUC-Ont-071317	Oreochromis niloticus	81.25	0.00e+00	781.00
IUUC-Oan-072952	Ornithorhynchus anatinus	89.92	0.00e+00	885.00
IUUC-Ocu-073913	Oryctolagus cuniculus	92.34	0.00e+00	939.00
IUUC-Ola-087024	Oryzias latipes	80.08	0.00e+00	821.00
IUUC-Oga-087945	Otolemur garnettii	92.54	0.00e+00	940.00
IUUC-Oar-089854	Ovis aries	91.33	0.00e+00	881.00
IUUC-Ptr-091486	Pan troglodytes	94.74	0.00e+00	952.00
IUUC-Pan-091738	Papio anubis	94.14	0.00e+00	948.00
IUUC-Psi-093953	Pelodiscus sinensis	89.11	0.00e+00	877.00
IUUC-Pma-094560	Petromyzon marinus	71.29	0.00e+00	731.00
IUUC-Pfo-097222	Poecilia formosa	79.35	0.00e+00	778.00
IUUC-Pca-100852	Procavia capensis	88.66	0.00e+00	881.00
IUUC-Pva-103130	Pteropus vampyrus	94.09	8.00e-119	420.00
IUUC-Rno-105848	Rattus norvegicus	85.45	0.00e+00	830.00
IUUC-Sha-106750	Sarcophilus harrisii	90.12	0.00e+00	890.00
IUUC-Sar-113749	Sorex araneus	83.20	0.00e+00	821.00
IUUC-Ssc-115691	Sus scrofa	88.89	0.00e+00	867.00
IUUC-Tgu-117365	Taeniopygia guttata	88.08	0.00e+00	828.00
IUUC-Tru-117595	Takifugu rubripes	78.43	0.00e+00	774.00
IUUC-Tsy-118973	Tarsius syrichta	70.44	4.00e-136	478.00
IUUC-Tni-120545	Tetraodon nigroviridis	78.51	0.00e+00	807.00
IUUC-Tbe-127976	Tupaia belangeri	71.86	0.00e+00	692.00
IUUC-Ttr-128472	Tursiops truncatus	91.30	0.00e+00	919.00
IUUC-Xtr-132621	Xenopus tropicalis	86.67	0.00e+00	841.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence