iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-047958

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01062068

Gene Name

Tbl1xr1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014252.2	ENSSTOT00000014258.2	ENSSTOP00000012770.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-55	182.3	199	237
UBD/Beta-Prp	8.80e-67	225.4	162	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W+++++++++
   Q: 199  GHTNEVNAIKWdPTgNLLASCSDDMTLKIWSMKQDNCVH 237
           8***********778*********************987 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           +  +v++ ++++ +a+ s+d +i v ++ +   +++++gh++ev+a+k++p+g++l+++s+D+t+k+w++++  cvh l++h+++++++
   Q: 162  PALDVDW-QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTI 249
           4444555.667777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 101  sfsp........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           ++sp        +    l+s+s d+t+r+wd++ g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ +tg l++  +g  t
   Q: 250  KWSPtgpgtnnpNAnLMLASASFDSTVRLWDVDRGICIH-TLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG--T 335
           777755555444222467777777777777777777777.7777777777777777777777777777777777777777777776..7 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlq 210
           + +  + ++  g  + + + dg+v + dl+
   Q: 336  GGIFEVCWNAAGDKVGASASDGSVCVLDLR 365
           777777777777777777777777776665 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MEVDGDVEIP PNKAVVLRGH ESEVFICAWN PVSDLLASGS GDSTARIWNL SENSTSGSTQ 60
LVLRHCIREG GQDVPSNKDV TSLDWNSEGT LLATGSYDGF ARIWTKDGNL ASTLGQHKGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGTGGTAC CGGATCTTCA GTTGCGCATC CCTACATCAA TGCACTGCCA ATGGTAAGAG 60
ACTCTCCAAC CCCGATTGTC AGTGTTTAAA GACTGTTATT ATCTTGAAAA TACTAAAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0017053--C:transcriptional repressor complex
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0060613--P:fat pad development
GO:0016042--P:lipid catabolic process
GO:0035264--P:multicellular organism growth
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0030814--P:regulation of cAMP metabolic process
GO:0090207--P:regulation of triglyceride metabolic process
GO:0002021--P:response to dietary excess
GO:0050872--P:white fat cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.71	1.00e-54	204.00
IUUC-Aml-001717	Ailuropoda melanoleuca	99.73	0.00e+00	737.00
IUUC-Atr-002514	Amborella trichopoda	65.38	8.00e-144	503.00
IUUC-Apl-003708	Anas platyrhynchos	99.45	0.00e+00	736.00
IUUC-Aca-004611	Anolis carolinensis	99.73	0.00e+00	738.00
IUUC-Aly-005622	Arabidopsis lyrata	58.40	1.00e-118	420.00
IUUC-Ath-007137	Arabidopsis thaliana	59.50	3.00e-120	425.00
IUUC-Ame-011601	Astyanax mexicanus	94.26	0.00e+00	700.00
IUUC-Bta-012418	Bos taurus	99.45	0.00e+00	761.00
IUUC-Bdi-014315	Brachypodium distachyon	61.62	2.00e-133	468.00
IUUC-Bol-016277	Brassica oleracea	60.00	2.00e-125	442.00
IUUC-Bra-016944	Brassica rapa	60.56	2.00e-125	442.00
IUUC-Cja-018832	Callithrix jacchus	100.00	0.00e+00	739.00
IUUC-Cfa-020029	Canis familiaris	100.00	0.00e+00	738.00
IUUC-Cpo-022080	Cavia porcellus	94.55	0.00e+00	696.00
IUUC-Csa-024075	Chlorocebus sabaeus	100.00	0.00e+00	738.00
IUUC-Cho-024872	Choloepus hoffmanni	100.00	1.00e-46	180.00
IUUC-Cme-027258	Cyanidioschyzon merolae	44.20	7.00e-89	320.00
IUUC-Dre-028075	Danio rerio	98.09	0.00e+00	719.00
IUUC-Dno-029196	Dasypus novemcinctus	100.00	0.00e+00	740.00
IUUC-Dor-030732	Dipodomys ordii	99.44	0.00e+00	715.00
IUUC-Ete-033150	Echinops telfairi	99.07	0.00e+00	639.00
IUUC-Eeu-034952	Erinaceus europaeus	85.91	2.00e-175	608.00
IUUC-Fca-035734	Felis catus	100.00	0.00e+00	739.00
IUUC-Fal-037185	Ficedula albicollis	99.73	0.00e+00	737.00
IUUC-Gmo-038870	Gadus morhua	94.26	0.00e+00	724.00
IUUC-Gga-041161	Gallus gallus	99.73	0.00e+00	737.00
IUUC-Gac-041844	Gasterosteus aculeatus	97.81	0.00e+00	751.00
IUUC-Gma-043369	Glycine max	61.54	3.00e-134	471.00
IUUC-Ggo-044882	Gorilla gorilla	100.00	0.00e+00	738.00
IUUC-Hsa-046488	Homo sapiens	100.00	0.00e+00	738.00
IUUC-Kpa-049338	Komagataella pastoris	28.91	1.00e-31	130.00
IUUC-Lch-050672	Latimeria chalumnae	98.63	0.00e+00	732.00
IUUC-Lpe-051084	Leersia perrieri	62.64	4.00e-135	474.00
IUUC-Loc-052030	Lepisosteus oculatus	98.36	0.00e+00	753.00
IUUC-Laf-054280	Loxodonta africana	99.73	0.00e+00	763.00
IUUC-Mcc-055203	Macaca mulatta	100.00	0.00e+00	739.00
IUUC-Meu-056563	Macropus eugenii	98.32	1.00e-133	469.00
IUUC-Mtr-058624	Medicago truncatula	60.44	2.00e-127	449.00
IUUC-Mga-059660	Meleagris gallopavo	99.73	0.00e+00	737.00
IUUC-Mvi-060557	Microbotryum violaceum	36.77	1.00e-69	257.00
IUUC-Mmr-060925	Microcebus murinus	100.00	0.00e+00	735.00
IUUC-Mdo-062078	Monodelphis domestica	99.45	0.00e+00	736.00
IUUC-Mmu-063603	Mus musculus	99.45	0.00e+00	734.00
IUUC-Mac-065508	Musa acuminata	61.80	3.00e-92	332.00
IUUC-Mpu-066741	Mustela putorius furo	100.00	0.00e+00	738.00
IUUC-Mlu-068152	Myotis lucifugus	100.00	0.00e+00	740.00
IUUC-Nle-069229	Nomascus leucogenys	100.00	0.00e+00	738.00
IUUC-Opr-070277	Ochotona princeps	84.96	2.00e-171	595.00
IUUC-Ont-072623	Oreochromis niloticus	98.09	0.00e+00	751.00
IUUC-Ocu-074280	Oryctolagus cuniculus	100.00	0.00e+00	739.00
IUUC-Oba-075618	Oryza barthii	59.62	3.00e-123	435.00
IUUC-Obr-076718	Oryza brachyantha	62.91	1.00e-135	476.00
IUUC-Ogl-077302	Oryza glaberrima	62.91	3.00e-135	474.00
IUUC-Ogu-078718	Oryza glumaepatula	62.91	3.00e-135	475.00
IUUC-Oin-079515	Oryza indica	56.57	2.00e-73	270.00
IUUC-Olo-080427	Oryza longistaminata	63.32	9.00e-131	460.00
IUUC-Ome-081696	Oryza meridionalis	61.26	5.00e-130	457.00
IUUC-Oni-082137	Oryza nivara	62.91	3.00e-135	475.00
IUUC-Opu-083505	Oryza punctata	59.34	5.00e-123	434.00
IUUC-Oru-085276	Oryza rufipogon	62.64	1.00e-134	473.00
IUUC-Osa-085791	Oryza sativa	62.91	3.00e-135	475.00
IUUC-Ola-087365	Oryzias latipes	97.81	0.00e+00	748.00
IUUC-Oga-088357	Otolemur garnettii	95.08	0.00e+00	686.00
IUUC-Oar-089214	Ovis aries	99.73	0.00e+00	764.00
IUUC-Ptr-091532	Pan troglodytes	100.00	0.00e+00	738.00
IUUC-Pan-091927	Papio anubis	100.00	0.00e+00	738.00
IUUC-Psi-093941	Pelodiscus sinensis	99.46	0.00e+00	731.00
IUUC-Pma-094105	Petromyzon marinus	80.28	4.00e-61	228.00
IUUC-Ppa-095868	Physcomitrella patens	66.57	1.00e-138	486.00
IUUC-Pfo-096158	Poecilia formosa	97.54	0.00e+00	749.00
IUUC-Pab-098705	Pongo abelii	100.00	0.00e+00	738.00
IUUC-Pop-098989	Populus trichocarpa	61.54	7.00e-127	446.00
IUUC-Pca-100256	Procavia capensis	99.45	0.00e+00	725.00
IUUC-Ppe-101572	Prunus persica	63.69	6.00e-127	447.00
IUUC-Pva-102616	Pteropus vampyrus	100.00	0.00e+00	725.00
IUUC-Rno-105411	Rattus norvegicus	99.73	0.00e+00	737.00
IUUC-Sce-106132	Saccharomyces cerevisiae	25.98	3.00e-32	132.00
IUUC-Sha-106636	Sarcophilus harrisii	99.45	0.00e+00	737.00
IUUC-Smo-109301	Selaginella moellendorffii	63.49	1.00e-141	496.00
IUUC-Sit-110710	Setaria italica	63.71	4.00e-141	494.00
IUUC-Sly-111336	Solanum lycopersicum	60.44	7.00e-128	450.00
IUUC-Sar-112971	Sorex araneus	87.85	0.00e+00	659.00
IUUC-Sbi-114420	Sorghum bicolor	63.19	6.00e-141	494.00
IUUC-Sre-115175	Sporisorium reilianum	42.45	1.00e-56	214.00
IUUC-Ssc-115695	Sus scrofa	100.00	0.00e+00	739.00
IUUC-Tgu-117009	Taeniopygia guttata	99.72	0.00e+00	721.00
IUUC-Tru-118581	Takifugu rubripes	97.54	0.00e+00	743.00
IUUC-Tni-119986	Tetraodon nigroviridis	97.54	0.00e+00	743.00
IUUC-Tca-121739	Theobroma cacao	56.87	8.00e-124	437.00
IUUC-Tae-125368	Triticum aestivum	61.62	1.00e-134	473.00
IUUC-Tur-126856	Triticum urartu	60.61	3.00e-61	228.00
IUUC-Tme-127126	Tuber melanosporum	38.42	4.00e-58	218.00
IUUC-Tbe-127767	Tupaia belangeri	97.42	0.00e+00	630.00
IUUC-Vpa-130768	Vicugna pacos	99.45	0.00e+00	726.00
IUUC-Xtr-132842	Xenopus tropicalis	94.54	0.00e+00	692.00
IUUC-Xma-134020	Xiphophorus maculatus	97.54	0.00e+00	749.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence