iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062845

Ensembl Protein ID

ENSMODP00000035924.3

UniProt Accession

F7A9R7; F7A9R7_MONDO

Protein Name

Uncharacterized protein

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000144.5	ENSMODT00000037512.4	ENSMODP00000035924.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-31	106.7	1545	1578
UBD/Beta-Prp	8.60e-42	143.5	1411	1614

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H+d+v++laf ++ ++l+s+++ g ikvW++  +
   Q: 1545 HKDWVCALAFvPGrPMLLSACRGGFIKVWNVENF 1578
           ***********999****************9765 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e +++++ ++p+g +++ +++ + ++vw+l+ ++++ +l+gh   v++l++++  +  d +v+Gs+d ++++++l +    +   
   Q: 1411 QGEHQINQIALNPTG-TILYAASGNSVRVWELNRFQPIGKLTGHIGPVMCLTVNQtsNHhDLVVTGSKDHYVKMFELAESIMGNIsp 1496
           45668*********9.8999999********************************984469*************9887665555566 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++++ + +
   Q: 1497 thnFEPPHYDGIECLAIQG--DVLFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRGGFIKVWNVENFTPI 1581
           666999************9..9*************************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
            + +gh+++++ + +   ++++ ++ssD  +++W 
   Q: 1582 GEIKGHDSPINAICTN--SKHIFTASSDCRVKLWS 1614
           ***********77777..****************6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MASQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDTWQ 60
EQIYTACVGK LIEGCFEGYN ATVLAYGQTG AGKTYTMGTG FDINTSEEEH GIIPRAIAHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCTCAGGG CCCCTGCCAC ATGGAGGGCG CACGGGCGAG AGGGGAGCTC CGGGGTTCTG 60
CTGCTGGCTC CCCATGAGCC CCGTATAAGC CGCCGCCGCT GCCGCCTCGG GGGAGCATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	89.57	0.00e+00	2675.00
IUUC-Aca-004506	Anolis carolinensis	82.68	0.00e+00	1647.00
IUUC-Ame-011515	Astyanax mexicanus	76.82	0.00e+00	1472.00
IUUC-Bta-013185	Bos taurus	72.74	0.00e+00	2076.00
IUUC-Cel-018402	Caenorhabditis elegans	51.25	5.00e-150	526.00
IUUC-Cja-018844	Callithrix jacchus	87.80	0.00e+00	2674.00
IUUC-Cfa-021187	Canis familiaris	90.73	0.00e+00	2749.00
IUUC-Cpo-022444	Cavia porcellus	88.73	0.00e+00	2727.00
IUUC-Csa-023852	Chlorocebus sabaeus	90.67	0.00e+00	2763.00
IUUC-Csv-026158	Ciona savignyi	53.77	3.00e-178	619.00
IUUC-Dre-027839	Danio rerio	74.87	0.00e+00	1430.00
IUUC-Dno-030058	Dasypus novemcinctus	85.49	0.00e+00	2645.00
IUUC-Dor-030673	Dipodomys ordii	86.70	0.00e+00	2570.00
IUUC-Ete-032705	Echinops telfairi	79.23	0.00e+00	867.00
IUUC-Eca-033885	Equus caballus	89.21	0.00e+00	2672.00
IUUC-Eeu-035338	Erinaceus europaeus	78.19	0.00e+00	2095.00
IUUC-Fca-035388	Felis catus	90.41	0.00e+00	2560.00
IUUC-Fal-037044	Ficedula albicollis	87.20	0.00e+00	2708.00
IUUC-Gmo-039034	Gadus morhua	67.74	0.00e+00	1262.00
IUUC-Gac-041328	Gasterosteus aculeatus	73.35	0.00e+00	2295.00
IUUC-Ggo-045392	Gorilla gorilla	90.11	0.00e+00	2742.00
IUUC-Hsa-046713	Homo sapiens	90.67	0.00e+00	2762.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	90.72	0.00e+00	1607.00
IUUC-Loc-052703	Lepisosteus oculatus	80.24	0.00e+00	2507.00
IUUC-Laf-054193	Loxodonta africana	81.86	0.00e+00	2394.00
IUUC-Mcc-055484	Macaca mulatta	89.13	0.00e+00	2717.00
IUUC-Meu-056278	Macropus eugenii	89.16	0.00e+00	1257.00
IUUC-Mga-059816	Meleagris gallopavo	83.80	0.00e+00	2584.00
IUUC-Mmr-061071	Microcebus murinus	87.41	0.00e+00	2660.00
IUUC-Mmu-063967	Mus musculus	90.93	0.00e+00	2732.00
IUUC-Mpu-066448	Mustela putorius furo	89.39	0.00e+00	2737.00
IUUC-Nle-070037	Nomascus leucogenys	89.48	0.00e+00	2113.00
IUUC-Opr-070325	Ochotona princeps	86.19	0.00e+00	2556.00
IUUC-Ont-071851	Oreochromis niloticus	74.18	0.00e+00	2327.00
IUUC-Oan-073615	Ornithorhynchus anatinus	86.92	0.00e+00	2549.00
IUUC-Ocu-073855	Oryctolagus cuniculus	90.56	0.00e+00	2725.00
IUUC-Ola-086703	Oryzias latipes	72.95	0.00e+00	2297.00
IUUC-Oga-088171	Otolemur garnettii	88.90	0.00e+00	2665.00
IUUC-Oar-089693	Ovis aries	73.17	0.00e+00	1181.00
IUUC-Ptr-090535	Pan troglodytes	89.38	0.00e+00	1733.00
IUUC-Pan-091917	Papio anubis	90.27	0.00e+00	2536.00
IUUC-Psi-093752	Pelodiscus sinensis	78.64	0.00e+00	1414.00
IUUC-Pfo-096827	Poecilia formosa	70.30	0.00e+00	1358.00
IUUC-Pab-098441	Pongo abelii	90.61	0.00e+00	2773.00
IUUC-Pca-100781	Procavia capensis	92.05	0.00e+00	877.00
IUUC-Pva-103099	Pteropus vampyrus	86.77	0.00e+00	1309.00
IUUC-Rno-105872	Rattus norvegicus	90.26	0.00e+00	2762.00
IUUC-Sha-107097	Sarcophilus harrisii	91.44	0.00e+00	2727.00
IUUC-Ssc-115638	Sus scrofa	89.27	0.00e+00	2378.00
IUUC-Tgu-116504	Taeniopygia guttata	85.87	0.00e+00	1684.00
IUUC-Tru-118242	Takifugu rubripes	74.09	0.00e+00	1486.00
IUUC-Ttr-128824	Tursiops truncatus	84.85	0.00e+00	2147.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence