iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042293

UUCD1 version

UUC-GaA-00701

Ensembl Protein ID

ENSGACP00000018160.1

UniProt Accession

G3PKN0; G3PKN0_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000013744.1	ENSGACT00000018195.1	ENSGACP00000018160.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.90e-92	309.0	495	709

Active Site

Position(s)	Description	Evidence
818	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           +sdlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f y+++ k  ++ n++s     e++  ++++G +lg+a++++ +ld+
   Q: 495  PSDLKKQLFVEFEGEQGVDEGGVSKEFFQLVLEEIFNPDIGMFSYDDDTKLFWF-NSSSL----ENEAQYTLVGLVLGLAIYNNCILDV 578
           799******************************************999888887.55554....67999******************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl++ +p   +slk+++e+   ++ee  + lt++  +++++g+   ++Lk++G++ipVt +N++e+v+ ++
   Q: 579  HFPMVVYRKLMGKKGTYLDLPDCHPVQGRSLKKLLEY-GGNVEED-MMLTYQiSHTDLFGNPMLHDLKEEGDQIPVTADNRQEFVDTYA 665
           *************************************.6677775.888888455667******************************* PP
   S: 179  eyrlkegikeqveafreGfneviplellslFteeelellicGee 222
           +y l++++++q++afr+Gf  v +++ l+++   e e+licG++
   Q: 666  DYVLNKSVERQFKAFRKGFLMVTKESPLKYLFRPEEEMLICGSR 709
           *****************************9999999******94 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

NRAAAKHLIE RYFQQLTDGC GNGDCTNEFC ASCRHFRPLD KNLAAAKALE LFKINAKLCN 60
PQPSNEDDPD DKMSETDAST TTEDFSDVHY LTENTVCAIL SFCEEQGDYS ALIRVVGRIF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAGAGCGG CTGCAAAGCA TCTAATCGAG CGCTACTTTC AGCAGTTAAC TGACGGCTGT 60
GGAAATGGCG ACTGCACGAA TGAGTTTTGC GCATCGTGTC GTCACTTTCG ACCCTTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gmo-038840	Gadus morhua	70.95	0.00e+00	1190.00
IUUC-Ont-072087	Oreochromis niloticus	79.00	0.00e+00	1371.00
IUUC-Ola-086833	Oryzias latipes	75.23	0.00e+00	1240.00
IUUC-Pfo-096868	Poecilia formosa	75.60	0.00e+00	1273.00
IUUC-Tru-117763	Takifugu rubripes	72.11	0.00e+00	1235.00
IUUC-Tni-120640	Tetraodon nigroviridis	70.37	0.00e+00	1167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence