iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086833

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04084019

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000015759.1	ENSORLT00000019737.1	ENSORLP00000019736.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.10e-105	352.2	514	840

Active Site

Position(s)	Description	Evidence
809	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           +sdlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f+y++n k  ++  ++s     e++  ++++G++lg+a++++ +ld+
   Q: 514  PSDLKKQLFVEFEGEQGVDEGGVSKEFFQLVLEEIFNPDIGMFTYDDNTKLFWFN-SSSL----ENEAQYTLIGIVLGLAIYNNCILDV 597
           799********************************************99999884.4454....67999******************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl++ +p ly+slke++e+   ++ee ++ ltf+  +++++g+   ++Lk++G++i Vt++N++e+v+l++
   Q: 598  HFPMVVYRKLMGKKGTFLDLSDSHPVLYQSLKELLEY-TGNVEE-DMMLTFQiSHTDLFGNPILYDLKEQGDQIAVTKANRQEFVDLYA 684
           *************************************.556666.59999994456669****************************** PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           +y+l++++++q++af++Gf  v +++ +  lF++ee+ellicG++++d+e+l+++t y+ggyt+d ++i+ Fwe++++fs+e+++ fLq
   Q: 685  DYILNTSVETQFKAFKKGFLMVTSESpMKYLFRPEEVELLICGSRKLDFEALERTTDYDGGYTKDTQVIKDFWETIHSFSDEQKRLFLQ 773
           **********************999945568********************************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+Tg++r+P+gG+ +lk   ++i k++sd drlP+s+TCfn L LPeYsske+l+e+Ll Ai++++gF++
   Q: 774  FTTGTDRAPVGGLGKLK---MIIAKNGSDtDRLPTSHTCFNALLLPEYSSKEKLRERLLKAITYAEGFGM 840
           *****************...8899978777**************************************97 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

RNRATAKKLI ERYFQQLTEG CGNTSCTNEF CASFQGFQPL DKNAAAAKAL DLFKANAKLC 60
DYYPSIKLRA DNVEMGNKMS TEDFSGTLKV DTKFYVRSVQ AVFKISVCFG VSDIHYLTEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAACAGAG CGACTGCTAA GAAGCTAATA GAGCGGTACT TTCAGCAGTT GACTGAAGGC 60
TGTGGAAACA CCAGCTGCAC AAATGAGTTC TGCGCATCCT TTCAGGGTTT TCAACCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003144	Amborella trichopoda	44.27	2.00e-94	339.00
IUUC-Cin-025643	Ciona intestinalis	44.20	0.00e+00	689.00
IUUC-Csv-026282	Ciona savignyi	44.05	0.00e+00	647.00
IUUC-Cme-027151	Cyanidioschyzon merolae	42.57	4.00e-98	353.00
IUUC-Gmo-038840	Gadus morhua	67.78	0.00e+00	1165.00
IUUC-Gac-042293	Gasterosteus aculeatus	75.00	0.00e+00	1274.00
IUUC-Lma-053245	Leptosphaeria maculans	36.70	4.00e-59	223.00
IUUC-Ont-072087	Oreochromis niloticus	82.75	0.00e+00	1404.00
IUUC-Pno-094886	Phaeosphaeria nodorum	35.08	3.00e-55	210.00
IUUC-Pfo-096868	Poecilia formosa	81.84	0.00e+00	1368.00
IUUC-Smo-108858	Selaginella moellendorffii	48.14	8.00e-112	397.00
IUUC-Tru-117763	Takifugu rubripes	73.13	0.00e+00	1238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence