iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004877.5	ENSBTAT00000062935.1	ENSBTAP00000054002.1
ENSBTAG00000004877.5	ENSBTAT00000006411.4	ENSBTAP00000006411.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.00e-06	28.3	7	50

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC + f   +d +    CgH+fh +Cl +w     ++ ++ +CP Cr
   Q: 7    CTICSDFFdhsRD-VAAIHCGHTFHSHCLIQW----FETAPSRTCPQCR 50
           9***776655344.88999*************....9***********8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MPIRALCTIC SDFFDHSRDV AAIHCGHTFH SHCLIQWFET APSRTCPQCR IQVGKRTIIN 60
KLYFDLAPEE ENVLDTEFLK NELDNTRALL SQKEKEKRDS QLIIDSLRDT LDERNATVES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCGTGGA GCCAAATTCG AAGCTAGTGA AGACGCGGAG GCACGGCCAC CAAGCTGGAC 60
CCGTCGCCGT TTCCTTGGCT ACCTCGGCTA CTCGAGACCA GTCATCATGC CTATCCGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005057--F:signal transducer activity, downstream of receptor
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032688--P:negative regulation of interferon-beta production
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001411	Ailuropoda melanoleuca	82.20	0.00e+00	733.00
IUUC-Atr-002646	Amborella trichopoda	28.10	9.00e-07	48.50
IUUC-Apl-003777	Anas platyrhynchos	58.38	4.00e-111	394.00
IUUC-Aca-004476	Anolis carolinensis	56.90	7.00e-144	503.00
IUUC-Ame-011706	Astyanax mexicanus	48.00	2.00e-08	50.10
IUUC-Cel-018227	Caenorhabditis elegans	23.81	1.00e-11	64.30
IUUC-Cja-019856	Callithrix jacchus	82.59	0.00e+00	769.00
IUUC-Cfa-020075	Canis familiaris	84.50	0.00e+00	820.00
IUUC-Cpo-022481	Cavia porcellus	77.54	0.00e+00	734.00
IUUC-Csa-023793	Chlorocebus sabaeus	81.74	0.00e+00	788.00
IUUC-Csv-026190	Ciona savignyi	34.19	2.00e-41	162.00
IUUC-Dre-027984	Danio rerio	49.48	7.00e-125	440.00
IUUC-Dno-029478	Dasypus novemcinctus	81.06	0.00e+00	765.00
IUUC-Dor-030526	Dipodomys ordii	60.04	2.00e-157	548.00
IUUC-Dme-032130	Drosophila melanogaster	31.03	1.00e-22	100.00
IUUC-Ete-033012	Echinops telfairi	70.76	0.00e+00	637.00
IUUC-Eca-034084	Equus caballus	87.29	0.00e+00	843.00
IUUC-Eeu-034579	Erinaceus europaeus	75.58	0.00e+00	629.00
IUUC-Fca-035772	Felis catus	86.20	0.00e+00	803.00
IUUC-Fal-037098	Ficedula albicollis	59.28	1.00e-138	486.00
IUUC-Gmo-038704	Gadus morhua	47.22	3.00e-107	381.00
IUUC-Gga-041109	Gallus gallus	54.64	4.00e-139	488.00
IUUC-Gac-042636	Gasterosteus aculeatus	49.10	4.00e-119	421.00
IUUC-Ggo-045184	Gorilla gorilla	81.74	0.00e+00	782.00
IUUC-Hsa-046651	Homo sapiens	81.53	0.00e+00	755.00
IUUC-Itr-048550	Ictidomys tridecemlineatus	82.20	0.00e+00	791.00
IUUC-Lch-049575	Latimeria chalumnae	55.72	3.00e-131	461.00
IUUC-Loc-051999	Lepisosteus oculatus	49.21	1.00e-118	419.00
IUUC-Lma-053133	Leptosphaeria maculans	39.29	1.00e-07	50.40
IUUC-Laf-053347	Loxodonta africana	82.63	0.00e+00	783.00
IUUC-Mcc-054668	Macaca mulatta	74.11	2.00e-82	298.00
IUUC-Meu-056862	Macropus eugenii	61.91	1.00e-159	556.00
IUUC-Mga-059443	Meleagris gallopavo	55.56	3.00e-114	405.00
IUUC-Mmr-061219	Microcebus murinus	78.60	0.00e+00	746.00
IUUC-Mdo-062103	Monodelphis domestica	69.36	0.00e+00	637.00
IUUC-Mmu-064005	Mus musculus	75.64	0.00e+00	724.00
IUUC-Mpu-066570	Mustela putorius furo	85.35	0.00e+00	797.00
IUUC-Mlu-067806	Myotis lucifugus	85.35	0.00e+00	799.00
IUUC-Nle-069123	Nomascus leucogenys	81.95	0.00e+00	772.00
IUUC-Opr-071063	Ochotona princeps	80.08	0.00e+00	771.00
IUUC-Ont-071973	Oreochromis niloticus	49.68	7.00e-124	437.00
IUUC-Oan-073278	Ornithorhynchus anatinus	70.21	4.00e-104	370.00
IUUC-Ocu-074582	Oryctolagus cuniculus	75.64	0.00e+00	687.00
IUUC-Oin-079866	Oryza indica	25.00	7.00e-07	49.30
IUUC-Osa-085981	Oryza sativa	25.00	7.00e-07	48.90
IUUC-Ola-086959	Oryzias latipes	47.59	2.00e-109	389.00
IUUC-Oga-088807	Otolemur garnettii	79.32	0.00e+00	723.00
IUUC-Oar-089273	Ovis aries	92.16	0.00e+00	877.00
IUUC-Ptr-090768	Pan troglodytes	81.95	0.00e+00	785.00
IUUC-Pan-091880	Papio anubis	81.74	0.00e+00	786.00
IUUC-Psi-093782	Pelodiscus sinensis	64.75	4.00e-138	484.00
IUUC-Pma-094365	Petromyzon marinus	40.18	6.00e-67	248.00
IUUC-Ppa-095896	Physcomitrella patens	26.19	1.00e-09	58.20
IUUC-Pfo-096068	Poecilia formosa	48.63	3.00e-114	405.00
IUUC-Pab-098063	Pongo abelii	79.87	0.00e+00	756.00
IUUC-Pca-100327	Procavia capensis	85.59	4.00e-171	593.00
IUUC-Pva-102924	Pteropus vampyrus	84.08	0.00e+00	784.00
IUUC-Rno-105799	Rattus norvegicus	76.48	0.00e+00	727.00
IUUC-Sha-107643	Sarcophilus harrisii	65.45	4.00e-158	550.00
IUUC-Sit-109687	Setaria italica	37.68	3.00e-07	50.10
IUUC-Sar-113187	Sorex araneus	73.25	0.00e+00	659.00
IUUC-Sbi-114760	Sorghum bicolor	37.68	3.00e-07	50.40
IUUC-Ssc-115838	Sus scrofa	93.18	3.00e-144	503.00
IUUC-Tgu-116674	Taeniopygia guttata	57.30	4.00e-131	461.00
IUUC-Tru-117753	Takifugu rubripes	44.49	1.00e-111	396.00
IUUC-Tsy-119416	Tarsius syrichta	67.05	9.00e-63	234.00
IUUC-Tni-120767	Tetraodon nigroviridis	47.66	9.00e-111	393.00
IUUC-Tca-121056	Theobroma cacao	33.33	1.00e-06	48.10
IUUC-Tur-126115	Triticum urartu	25.29	8.00e-07	49.70
IUUC-Tbe-128001	Tupaia belangeri	49.16	1.00e-80	293.00
IUUC-Ttr-128687	Tursiops truncatus	90.02	0.00e+00	872.00
IUUC-Vvi-130955	Vitis vinifera	39.39	7.00e-08	52.40
IUUC-Xtr-131905	Xenopus tropicalis	53.91	6.00e-137	480.00
IUUC-Xma-133304	Xiphophorus maculatus	48.84	2.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence