iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041837

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 3a

Genbank Nucleotide ID

EF544595

Gene Name

socs3; SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000011015.1	ENSGACT00000014599.1	ENSGACP00000014573.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	55.90	4.00e-64	241.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MVTLSKFDSA MSSSLLDSSM RFPQRYKTFA SKAQYQMVLA TLHKLQESGF YWAAITGKDA 60
NAMLADETIG TFLVRDSSDN RHLFALSVKT ASGTKNLRIQ CDASSFYLQT DPKNIHSVPH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTCTTGGC AGCAGTCGGG CTGCTTACAA ACAAGAGAAA AAAAGTCAGG AGTTTATCGC 60
CAGAGAATTT ACGCCGAGAT ATACTCGCGT TTCATTCAAA GGAGCGAATT CGGACGAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	56.10	1.00e-62	232.00
IUUC-Apl-003607	Anas platyrhynchos	62.44	3.00e-61	227.00
IUUC-Aca-005063	Anolis carolinensis	61.05	1.00e-64	239.00
IUUC-Ame-010859	Astyanax mexicanus	60.71	5.00e-75	273.00
IUUC-Bta-012817	Bos taurus	54.94	8.00e-64	236.00
IUUC-Cja-019605	Callithrix jacchus	55.02	3.00e-63	234.00
IUUC-Cfa-021231	Canis familiaris	55.46	7.00e-63	233.00
IUUC-Cpo-022003	Cavia porcellus	54.74	2.00e-62	232.00
IUUC-Csa-023511	Chlorocebus sabaeus	55.46	2.00e-63	234.00
IUUC-Dre-028536	Danio rerio	67.14	1.00e-79	288.00
IUUC-Dno-029003	Dasypus novemcinctus	56.14	6.00e-64	236.00
IUUC-Eca-034205	Equus caballus	49.72	7.00e-42	162.00
IUUC-Fca-036317	Felis catus	56.59	2.00e-63	234.00
IUUC-Gmo-038777	Gadus morhua	57.27	7.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	60.56	4.00e-60	223.00
IUUC-Ggo-045620	Gorilla gorilla	55.46	2.00e-63	234.00
IUUC-Hsa-046909	Homo sapiens	55.46	2.00e-63	234.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	53.36	5.00e-63	233.00
IUUC-Lch-049510	Latimeria chalumnae	62.80	1.00e-72	265.00
IUUC-Loc-052863	Lepisosteus oculatus	74.16	3.00e-83	300.00
IUUC-Laf-054136	Loxodonta africana	54.74	3.00e-63	234.00
IUUC-Mcc-055383	Macaca mulatta	55.46	2.00e-63	234.00
IUUC-Meu-056153	Macropus eugenii	53.91	6.00e-64	236.00
IUUC-Mmr-061185	Microcebus murinus	55.22	9.00e-63	233.00
IUUC-Mdo-061819	Monodelphis domestica	54.15	4.00e-64	237.00
IUUC-Mmu-064231	Mus musculus	56.33	5.00e-65	240.00
IUUC-Mpu-066691	Mustela putorius furo	55.46	7.00e-63	233.00
IUUC-Mlu-067673	Myotis lucifugus	55.65	1.00e-64	239.00
IUUC-Ont-072406	Oreochromis niloticus	76.10	2.00e-87	314.00
IUUC-Oan-073249	Ornithorhynchus anatinus	57.07	2.00e-62	231.00
IUUC-Ocu-074935	Oryctolagus cuniculus	66.67	3.00e-20	89.40
IUUC-Ogu-078262	Oryza glumaepatula	28.26	9.00e-01	29.30
IUUC-Ola-087373	Oryzias latipes	49.47	1.00e-51	196.00
IUUC-Oga-088041	Otolemur garnettii	55.70	3.00e-63	234.00
IUUC-Oar-089646	Ovis aries	52.36	7.00e-59	219.00
IUUC-Ptr-091502	Pan troglodytes	55.46	2.00e-63	234.00
IUUC-Pan-091934	Papio anubis	55.46	2.00e-63	234.00
IUUC-Pfo-096412	Poecilia formosa	55.68	3.00e-53	201.00
IUUC-Pab-098554	Pongo abelii	55.46	2.00e-63	234.00
IUUC-Rno-105874	Rattus norvegicus	56.77	2.00e-65	241.00
IUUC-Sha-107151	Sarcophilus harrisii	53.45	1.00e-63	236.00
IUUC-Ssc-115722	Sus scrofa	54.12	2.00e-42	164.00
IUUC-Tgu-117151	Taeniopygia guttata	60.56	1.00e-59	222.00
IUUC-Tru-118428	Takifugu rubripes	79.51	2.00e-90	324.00
IUUC-Tni-120590	Tetraodon nigroviridis	77.56	4.00e-87	313.00
IUUC-Ttr-129065	Tursiops truncatus	54.94	7.00e-63	233.00
IUUC-Xtr-132167	Xenopus tropicalis	54.63	4.00e-64	236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence