iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023493

Ensembl Protein ID

ENSCSAP00000007200.1

UniProt Accession

A0A0D9RF11; A0A0D9RF11_CHLSB

Genbank Protein ID

ENSCSAP00000007200

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01047000

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000010979.1	ENSCSAT00000009068.1	ENSCSAP00000007200.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.60e-49	167.8	50	239

Active Site

Position(s)	Description	Evidence
57	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
60	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
233		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s+sd
   Q: 50   AIRKTKGDGNCFYRALGYSylesllgksreifkfkervlqtpndllaagfeehkfrnffnafysvvelvekdgsvssLLKVFNDQSASD 138
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts+++++++dff++fi+e++d+k+fc+++vep+a+ +++i+i+aL+q+Ls++++v++vd++++    +l++++fpe++ +
   Q: 139  HIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATeCDHIQITALSQALSIALQVEYVDEMDT----ALNHHVFPEAA-T 222
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 223  PSVYLLYKTSHYNILYA 239
           ***************97 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

HSISSFPIFQ SETSFNLISE KCDILSILRD HPENRIYRRK IEELSKRFTA IRKTKGDGNC 60
FYRALGYSYL ESLLGKSREI FKFKERVLQT PNDLLAAGFE EHKFRNFFNA FYSVVELVEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAGCATTT CTTCCTTCCC TATCTTCCAG AGTGAAACAT CTTTCAACCT AATATCAGAA 60
AAATGTGACA TTCTATCCAT TCTTCGGGAC CATCCTGAAA ACAGGATTTA CCGGAGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	95.28	6.00e-132	462.00
IUUC-Bta-012766	Bos taurus	95.71	2.00e-131	461.00
IUUC-Cja-019480	Callithrix jacchus	96.57	3.00e-133	467.00
IUUC-Cfa-021106	Canis familiaris	95.71	9.00e-133	465.00
IUUC-Cpo-022187	Cavia porcellus	94.47	2.00e-131	461.00
IUUC-Cho-024411	Choloepus hoffmanni	75.12	1.00e-83	301.00
IUUC-Dno-029346	Dasypus novemcinctus	95.26	4.00e-131	460.00
IUUC-Dor-031012	Dipodomys ordii	95.28	4.00e-132	463.00
IUUC-Ete-032266	Echinops telfairi	85.78	2.00e-117	414.00
IUUC-Eca-033356	Equus caballus	96.57	2.00e-132	464.00
IUUC-Eeu-034775	Erinaceus europaeus	95.69	2.00e-131	461.00
IUUC-Fca-035363	Felis catus	93.99	4.00e-130	456.00
IUUC-Ggo-045023	Gorilla gorilla	99.57	9.00e-137	478.00
IUUC-Hsa-046984	Homo sapiens	100.00	2.00e-137	480.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	95.28	3.00e-132	463.00
IUUC-Lch-050514	Latimeria chalumnae	60.89	3.00e-83	301.00
IUUC-Loc-052003	Lepisosteus oculatus	49.78	1.00e-63	235.00
IUUC-Laf-054382	Loxodonta africana	94.85	1.00e-131	462.00
IUUC-Mcc-055516	Macaca mulatta	99.57	2.00e-137	481.00
IUUC-Meu-056038	Macropus eugenii	87.83	6.00e-99	352.00
IUUC-Mmr-060918	Microcebus murinus	96.14	1.00e-132	465.00
IUUC-Mdo-062638	Monodelphis domestica	89.22	1.00e-123	435.00
IUUC-Mmu-063973	Mus musculus	91.50	1.00e-131	462.00
IUUC-Mpu-066013	Mustela putorius furo	96.12	2.00e-132	464.00
IUUC-Mlu-067509	Myotis lucifugus	93.99	1.00e-128	451.00
IUUC-Nle-069673	Nomascus leucogenys	100.00	2.00e-137	480.00
IUUC-Opr-070761	Ochotona princeps	87.27	2.00e-80	290.00
IUUC-Oan-072922	Ornithorhynchus anatinus	81.22	2.00e-111	394.00
IUUC-Ocu-074643	Oryctolagus cuniculus	94.42	2.00e-130	457.00
IUUC-Oni-082026	Oryza nivara	28.32	5.00e-16	79.30
IUUC-Oru-084761	Oryza rufipogon	28.32	5.00e-16	79.30
IUUC-Ola-086603	Oryzias latipes	44.91	2.00e-51	194.00
IUUC-Oga-088936	Otolemur garnettii	95.73	1.00e-132	464.00
IUUC-Oar-089460	Ovis aries	95.76	3.00e-133	467.00
IUUC-Ptr-090805	Pan troglodytes	99.57	6.00e-137	479.00
IUUC-Pan-091969	Papio anubis	100.00	2.00e-137	480.00
IUUC-Pab-098476	Pongo abelii	99.58	5.00e-140	489.00
IUUC-Pca-100252	Procavia capensis	89.00	1.00e-51	196.00
IUUC-Pva-102204	Pteropus vampyrus	94.42	2.00e-131	461.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.40e-02	31.60
IUUC-Rno-105062	Rattus norvegicus	94.85	2.00e-131	461.00
IUUC-Sha-106968	Sarcophilus harrisii	89.22	9.00e-124	436.00
IUUC-Sar-113295	Sorex araneus	95.26	3.00e-129	453.00
IUUC-Ssc-115288	Sus scrofa	95.26	1.00e-130	458.00
IUUC-Tni-120440	Tetraodon nigroviridis	38.96	3.00e-42	164.00
IUUC-Tbe-127717	Tupaia belangeri	94.59	4.00e-78	282.00
IUUC-Ttr-128221	Tursiops truncatus	76.72	9.00e-100	355.00
IUUC-Uma-129443	Ustilago maydis	33.03	1.00e-24	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence