iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001600

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01123299

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000002687.1	ENSAMET00000002951.1	ENSAMEP00000002831.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.40e-48	162.7	18	156

Active Site

Position(s)	Description	Evidence
96	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 18   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 106
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 107  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 156
           999*9******************************************998 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

AAAMARPLVP SSQKALLLEL KGLQEEPVEG FRVTLVDEGD LYNWEVAIFG PPNTYYEGGY 60
FKARLKFPID YPYSPPAFRF LTKMWHPNIY ETGDVCISIL HPPVDDPQSG ELPSERWNPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCCGCCA TGGCCCGGCC GCTGGTGCCC AGCTCGCAGA AGGCGCTGCT GCTCGAGCTC 60
AAGGGGCTGC AGGAGGAGCC GGTGGAGGGC TTCCGTGTGA CTCTGGTGGA CGAGGGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	85.03	2.00e-75	274.00
IUUC-Aca-004589	Anolis carolinensis	85.22	8.00e-105	372.00
IUUC-Ate-010563	Aspergillus terreus	42.04	4.00e-36	144.00
IUUC-Ame-011425	Astyanax mexicanus	87.02	1.00e-108	385.00
IUUC-Bta-012516	Bos taurus	99.52	6.00e-122	429.00
IUUC-Cel-018460	Caenorhabditis elegans	65.78	8.00e-72	263.00
IUUC-Cja-018852	Callithrix jacchus	89.91	4.00e-104	370.00
IUUC-Cfa-020203	Canis familiaris	99.55	2.00e-121	427.00
IUUC-Cpo-022139	Cavia porcellus	91.23	8.00e-121	425.00
IUUC-Csa-023371	Chlorocebus sabaeus	98.66	1.00e-122	431.00
IUUC-Cho-024999	Choloepus hoffmanni	73.33	1.00e-23	102.00
IUUC-Cin-025257	Ciona intestinalis	68.91	7.00e-82	296.00
IUUC-Csv-025954	Ciona savignyi	67.35	2.00e-82	298.00
IUUC-Dre-028367	Danio rerio	89.05	3.00e-108	384.00
IUUC-Dno-029368	Dasypus novemcinctus	86.32	2.00e-99	354.00
IUUC-Dor-030875	Dipodomys ordii	99.11	2.00e-123	434.00
IUUC-Dme-032106	Drosophila melanogaster	71.79	4.00e-85	308.00
IUUC-Ete-033001	Echinops telfairi	85.09	8.00e-56	208.00
IUUC-Eca-034221	Equus caballus	84.93	3.00e-74	270.00
IUUC-Fca-035832	Felis catus	99.40	2.00e-96	344.00
IUUC-Fal-037135	Ficedula albicollis	85.22	3.00e-102	363.00
IUUC-Gmo-039414	Gadus morhua	90.05	2.00e-109	387.00
IUUC-Gga-040694	Gallus gallus	96.19	7.00e-124	436.00
IUUC-Gac-042485	Gasterosteus aculeatus	88.56	4.00e-109	386.00
IUUC-Ggo-044806	Gorilla gorilla	99.12	2.00e-124	437.00
IUUC-Hsa-046245	Homo sapiens	99.11	1.00e-122	431.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	97.97	2.00e-84	304.00
IUUC-Lch-049845	Latimeria chalumnae	90.05	2.00e-109	388.00
IUUC-Loc-052932	Lepisosteus oculatus	91.54	4.00e-111	393.00
IUUC-Laf-053860	Loxodonta africana	84.73	4.00e-104	370.00
IUUC-Mcc-054665	Macaca mulatta	95.09	1.00e-115	408.00
IUUC-Meu-056681	Macropus eugenii	79.80	2.00e-97	348.00
IUUC-Mga-060075	Meleagris gallopavo	94.96	1.00e-123	434.00
IUUC-Mmr-061165	Microcebus murinus	98.21	2.00e-121	427.00
IUUC-Mdo-061825	Monodelphis domestica	97.77	2.00e-120	424.00
IUUC-Mmu-064168	Mus musculus	100.00	9.00e-121	425.00
IUUC-Mpu-066009	Mustela putorius furo	100.00	3.00e-132	463.00
IUUC-Mlu-067397	Myotis lucifugus	82.74	7.00e-98	349.00
IUUC-Nle-070152	Nomascus leucogenys	89.91	6.00e-58	214.00
IUUC-Opr-070826	Ochotona princeps	93.49	2.00e-109	388.00
IUUC-Ont-071745	Oreochromis niloticus	90.15	1.00e-110	392.00
IUUC-Oan-073287	Ornithorhynchus anatinus	91.10	5.00e-119	419.00
IUUC-Ocu-074902	Oryctolagus cuniculus	95.63	2.00e-116	411.00
IUUC-Ola-086976	Oryzias latipes	89.39	4.00e-108	383.00
IUUC-Oga-088845	Otolemur garnettii	97.36	7.00e-128	449.00
IUUC-Oar-089383	Ovis aries	84.73	4.00e-104	370.00
IUUC-Ptr-090916	Pan troglodytes	99.03	9.00e-118	415.00
IUUC-Pan-092577	Papio anubis	98.66	1.00e-122	431.00
IUUC-Psi-093039	Pelodiscus sinensis	94.38	4.00e-89	320.00
IUUC-Pma-094368	Petromyzon marinus	82.00	1.00e-73	268.00
IUUC-Pfo-096435	Poecilia formosa	89.55	8.00e-110	389.00
IUUC-Pab-098200	Pongo abelii	99.02	2.00e-111	394.00
IUUC-Pca-100169	Procavia capensis	86.43	6.00e-66	243.00
IUUC-Pva-102875	Pteropus vampyrus	99.39	1.00e-85	308.00
IUUC-Rno-106079	Rattus norvegicus	100.00	9.00e-121	425.00
IUUC-Sha-107364	Sarcophilus harrisii	85.22	8.00e-105	372.00
IUUC-Sar-112992	Sorex araneus	81.37	1.00e-95	342.00
IUUC-Ssc-115699	Sus scrofa	90.91	2.00e-88	317.00
IUUC-Tgu-117466	Taeniopygia guttata	94.07	1.00e-121	428.00
IUUC-Tru-117589	Takifugu rubripes	84.39	1.00e-103	368.00
IUUC-Tsy-118797	Tarsius syrichta	84.78	2.00e-69	254.00
IUUC-Tni-120864	Tetraodon nigroviridis	86.07	2.00e-105	374.00
IUUC-Tbe-128014	Tupaia belangeri	84.73	4.00e-104	370.00
IUUC-Ttr-128729	Tursiops truncatus	97.74	6.00e-90	322.00
IUUC-Vpa-130680	Vicugna pacos	85.42	2.00e-73	267.00
IUUC-Xtr-132285	Xenopus tropicalis	89.50	1.00e-117	415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence