iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036737

Ensembl Protein ID

ENSFALP00000012712.1

UniProt Accession

U3KCF8; U3KCF8_FICAL

Genbank Protein ID

ENSFALP00000012712

Protein Name

Coronin

Genbank Nucleotide ID

AGTO01011732

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012176.1	ENSFALT00000012762.1	ENSFALP00000012712.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-17	60.7	80	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d+ ++sGs D+t++vW +
   Q: 80   GHTGPVLDIDWcphNDHVIASGSEDCTVMVWQI 112
           8***********977799*************85 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KTDQCYDDIR VSRVTWDSTF CAVNPSFVAI IVEASGGGAF 60
LVLPLHKTGR IDKSYPTVCG HTGPVLDIDW CPHNDHVIAS GSEDCTVMVW QIPENGLSQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGA 60
TCCCTGTCCC CATCCCTCGC AGGGCCCCCC CATCCCCTTC CCCGTCCATG TCCCCATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015505--Coronin
IPR003143--Cyt_cd1_C
IPR015048--DUF1899
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	82.17	0.00e+00	837.00
IUUC-Aca-005056	Anolis carolinensis	81.47	0.00e+00	809.00
IUUC-Ago-007901	Ashbya gossypii	41.03	7.00e-89	321.00
IUUC-Bta-012984	Bos taurus	83.33	0.00e+00	842.00
IUUC-Cja-019498	Callithrix jacchus	82.58	0.00e+00	841.00
IUUC-Cfa-020937	Canis familiaris	90.14	0.00e+00	806.00
IUUC-Cpo-021866	Cavia porcellus	80.74	0.00e+00	824.00
IUUC-Csa-023561	Chlorocebus sabaeus	82.86	0.00e+00	844.00
IUUC-Dno-029770	Dasypus novemcinctus	79.31	0.00e+00	796.00
IUUC-Dor-030989	Dipodomys ordii	82.38	0.00e+00	832.00
IUUC-Eca-033901	Equus caballus	82.58	0.00e+00	830.00
IUUC-Fca-036494	Felis catus	82.79	0.00e+00	825.00
IUUC-Ggo-045035	Gorilla gorilla	82.65	0.00e+00	841.00
IUUC-Hsa-046154	Homo sapiens	82.65	0.00e+00	838.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	83.20	0.00e+00	825.00
IUUC-Laf-054566	Loxodonta africana	82.17	0.00e+00	827.00
IUUC-Mcc-054879	Macaca mulatta	82.86	0.00e+00	842.00
IUUC-Mmr-060910	Microcebus murinus	83.03	0.00e+00	847.00
IUUC-Mmu-063455	Mus musculus	81.76	0.00e+00	845.00
IUUC-Mpu-066350	Mustela putorius furo	83.94	0.00e+00	846.00
IUUC-Mlu-067353	Myotis lucifugus	83.40	0.00e+00	833.00
IUUC-Nle-069161	Nomascus leucogenys	82.65	0.00e+00	835.00
IUUC-Opr-071106	Ochotona princeps	83.61	0.00e+00	839.00
IUUC-Oga-088805	Otolemur garnettii	82.79	0.00e+00	839.00
IUUC-Ptr-091484	Pan troglodytes	82.86	0.00e+00	840.00
IUUC-Pan-091843	Papio anubis	82.24	0.00e+00	833.00
IUUC-Pab-097835	Pongo abelii	82.65	0.00e+00	840.00
IUUC-Pca-100411	Procavia capensis	90.14	0.00e+00	692.00
IUUC-Pva-102659	Pteropus vampyrus	82.79	0.00e+00	842.00
IUUC-Rno-106070	Rattus norvegicus	81.35	0.00e+00	838.00
IUUC-Sha-106609	Sarcophilus harrisii	91.55	0.00e+00	693.00
IUUC-Sar-113292	Sorex araneus	76.09	1.00e-176	612.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence