iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067485

Ensembl Protein ID

ENSMLUP00000002182.2

UniProt Accession

G1NXS2; G1NXS2_MYOLU

Genbank Protein ID

ENSMLUP00000002182

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02000317

Gene Name

WDR36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002381.2	ENSMLUT00000002401.2	ENSMLUP00000002182.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-20	70.8	569	606
UBD/Beta-Prp	8.30e-49	166.4	237	527

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ ++++af +d + l+s+s D++i+ WDl +g l+
   Q: 569  GHQGQINDMAFsPDgRWLISASMDCSIRTWDLPSGCLI 606
           8***********99999***************999876 PP

UBD/Beta-Prp

   S: 11   svitcvkf...spdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvw....dlstgkcvhtlk 91
           ++it++ f   +++ +++a+gs  g i +wd++++k++ ++   h+ +++ ++f +++++lvt + D++++vw    +   g  ++   
   Q: 237  GPITSISFrtvTDGHPIMAAGSPCGHIGLWDLEDKKFINQMrNAHSTAIAGLTFLHREPLLVTNGADNALRVWifdgPTGEGRLLRFRM 325
           57888888888999***************************99******************************7765555899999999 PP
   S: 92   ghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee..................tlsghdgvvncvvvhp...dg.nllvsGsl 157
           gh++ ++ ++++  +g+ ++s+s+d t++ + + +++  ++                  tls++   ++  +  +   ++ + +++++ 
   Q: 326  GHSAPLTKIRYYGqNGQQILSASQDGTLQSFSTIHEKFNKSlghglinkkrvkrkglqnTLSVRLPPITKFAAEEareSDwDGIIACHQ 414
           ***********99788**************99888888887999999999988888888444444444444333211022345666665 PP
   S: 158  Dr.tvrlWdlktgkllrtl...tgghtdsvysls..fdsngkelvsgsldgtvklwdlq...tgecvrtlnghtdnvksvrfspnderl 237
            +  +  W+ ++ ++   +   ++ ++d+++ ++  ++s g++ v g   gtv ++++q   +     + ++h+  v+ v+++  +++ 
   Q: 415  GKlSCSTWNYQRSTIGSYFlkpKELKKDDITATAvdITSCGNFAVIGLSSGTVDVYNMQsgiHRGRFGEDQAHKGSVRGVAVDGLNQLT 503
           442577787777777777788855567777766622666669*****************6653334777799***************** PP
   S: 238  vsgssDgsiriWdlrsgdllktlq 261
           ++++s+g +++W+ +++ l+++++
   Q: 504  ITTGSEGLLKFWNFKNKILIHSVS 527
           *************99998887765 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

SAAMERDAGG RSASALFAGF RALGLFSNDI PHVVRFNALK RRFYVTTCVG KSFHTYDVQK 60
LSLVAVSNSL PQDICCLAAD GRLVFAAYGN VFSAFARNKE VVHTFKGHKA EIHLLQPFGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGCAGCGA TGGAGCGGGA CGCAGGAGGC CGCTCGGCCA GCGCACTGTT CGCAGGATTC 60
CGGGCCTTAG GGCTTTTCAG CAACGACATT CCACACGTGG TGCGGTTCAA CGCGCTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030516--P:regulation of axon extension
GO:0001895--P:retina homeostasis
GO:0006364--P:rRNA processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	36.18	7.00e-147	514.00
IUUC-Aml-002289	Ailuropoda melanoleuca	95.23	0.00e+00	1714.00
IUUC-Atr-002859	Amborella trichopoda	32.87	1.00e-122	434.00
IUUC-Apl-003505	Anas platyrhynchos	74.70	0.00e+00	1221.00
IUUC-Aca-004339	Anolis carolinensis	72.63	0.00e+00	1302.00
IUUC-Aly-005913	Arabidopsis lyrata	36.60	2.00e-156	546.00
IUUC-Ath-006767	Arabidopsis thaliana	37.12	9.00e-159	554.00
IUUC-Ago-007763	Ashbya gossypii	31.58	2.00e-119	424.00
IUUC-Acl-008275	Aspergillus clavatus	33.29	3.00e-91	329.00
IUUC-Afl-008457	Aspergillus flavus	32.50	6.00e-88	318.00
IUUC-Afu-008914	Aspergillus fumigatus	33.74	3.00e-103	369.00
IUUC-Ani-009225	Aspergillus nidulans	31.95	3.00e-100	360.00
IUUC-Aor-010046	Aspergillus oryzae	31.14	5.00e-112	399.00
IUUC-Ate-010337	Aspergillus terreus	33.47	3.00e-113	402.00
IUUC-Ame-010963	Astyanax mexicanus	67.23	0.00e+00	1211.00
IUUC-Bgr-011973	Blumeria graminis	31.23	9.00e-113	401.00
IUUC-Bta-012462	Bos taurus	92.78	0.00e+00	1656.00
IUUC-Bci-013940	Botrytis cinerea	31.33	7.00e-115	408.00
IUUC-Bdi-014725	Brachypodium distachyon	35.83	1.00e-148	520.00
IUUC-Bol-016534	Brassica oleracea	36.13	2.00e-151	530.00
IUUC-Bra-016781	Brassica rapa	35.58	6.00e-149	521.00
IUUC-Cel-018581	Caenorhabditis elegans	28.34	6.00e-93	335.00
IUUC-Cja-019675	Callithrix jacchus	93.20	0.00e+00	1697.00
IUUC-Cfa-020118	Canis familiaris	93.31	0.00e+00	1649.00
IUUC-Cpo-021798	Cavia porcellus	91.75	0.00e+00	1599.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	29.41	1.00e-27	118.00
IUUC-Csa-023547	Chlorocebus sabaeus	94.11	0.00e+00	1681.00
IUUC-Cho-024518	Choloepus hoffmanni	82.72	0.00e+00	859.00
IUUC-Cin-025339	Ciona intestinalis	45.92	0.00e+00	785.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	30.42	3.00e-114	406.00
IUUC-Cne-026859	Cryptococcus neoformans	34.78	2.00e-143	503.00
IUUC-Cme-027173	Cyanidioschyzon merolae	28.25	8.00e-88	318.00
IUUC-Dre-027733	Danio rerio	64.89	0.00e+00	1197.00
IUUC-Dno-029439	Dasypus novemcinctus	93.31	0.00e+00	1654.00
IUUC-Dor-030329	Dipodomys ordii	79.33	0.00e+00	1362.00
IUUC-Dse-031511	Dothistroma septosporum	29.92	8.00e-105	375.00
IUUC-Dme-031694	Drosophila melanogaster	40.18	0.00e+00	683.00
IUUC-Ete-032930	Echinops telfairi	85.91	0.00e+00	1368.00
IUUC-Eca-033302	Equus caballus	95.44	0.00e+00	1702.00
IUUC-Eeu-034516	Erinaceus europaeus	92.44	0.00e+00	1709.00
IUUC-Fca-036064	Felis catus	94.78	0.00e+00	1672.00
IUUC-Fal-037024	Ficedula albicollis	72.15	0.00e+00	1299.00
IUUC-Fox-037787	Fusarium oxysporum	29.50	5.00e-96	345.00
IUUC-Fso-038378	Fusarium solani	29.46	5.00e-98	352.00
IUUC-Gmo-039637	Gadus morhua	53.04	1.00e-152	533.00
IUUC-Ggr-040108	Gaeumannomyces graminis	29.54	6.00e-106	379.00
IUUC-Gga-040982	Gallus gallus	73.48	0.00e+00	1330.00
IUUC-Gac-041565	Gasterosteus aculeatus	56.49	0.00e+00	951.00
IUUC-Gma-043185	Glycine max	35.15	2.00e-152	533.00
IUUC-Ggo-045463	Gorilla gorilla	94.22	0.00e+00	1720.00
IUUC-Hsa-045675	Homo sapiens	93.89	0.00e+00	1711.00
IUUC-Hvu-047352	Hordeum vulgare	34.96	4.00e-131	462.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	92.55	0.00e+00	1697.00
IUUC-Kpa-049164	Komagataella pastoris	33.26	4.00e-112	399.00
IUUC-Lch-050476	Latimeria chalumnae	69.54	0.00e+00	1276.00
IUUC-Lpe-051556	Leersia perrieri	28.30	3.00e-92	332.00
IUUC-Loc-052820	Lepisosteus oculatus	68.42	0.00e+00	1233.00
IUUC-Lma-052961	Leptosphaeria maculans	32.81	1.00e-106	381.00
IUUC-Laf-054006	Loxodonta africana	91.15	0.00e+00	1620.00
IUUC-Mcc-055037	Macaca mulatta	94.00	0.00e+00	1710.00
IUUC-Mor-057280	Magnaporthe oryzae	30.23	3.00e-109	389.00
IUUC-Mpo-057408	Magnaporthe poae	29.38	3.00e-103	370.00
IUUC-Mtr-058473	Medicago truncatula	34.39	5.00e-151	528.00
IUUC-Mla-058892	Melampsora laricipopulina	34.16	1.00e-119	424.00
IUUC-Mga-059598	Meleagris gallopavo	62.28	0.00e+00	1033.00
IUUC-Mvi-060334	Microbotryum violaceum	34.36	1.00e-119	424.00
IUUC-Mmr-061239	Microcebus murinus	93.44	0.00e+00	1664.00
IUUC-Mdo-062471	Monodelphis domestica	81.35	0.00e+00	1429.00
IUUC-Mmu-063872	Mus musculus	87.89	0.00e+00	1640.00
IUUC-Mac-064631	Musa acuminata	34.70	3.00e-133	469.00
IUUC-Mpu-066039	Mustela putorius furo	95.54	0.00e+00	1721.00
IUUC-Nfi-068319	Neosartorya fischeri	29.79	9.00e-102	365.00
IUUC-Ncr-068725	Neurospora crassa	29.87	4.00e-103	369.00
IUUC-Nle-069050	Nomascus leucogenys	93.89	0.00e+00	1711.00
IUUC-Opr-070437	Ochotona princeps	78.52	6.00e-139	488.00
IUUC-Ont-071574	Oreochromis niloticus	58.88	0.00e+00	1033.00
IUUC-Oan-072826	Ornithorhynchus anatinus	76.64	0.00e+00	1365.00
IUUC-Ocu-073995	Oryctolagus cuniculus	93.42	0.00e+00	1623.00
IUUC-Oba-075407	Oryza barthii	32.64	9.00e-121	427.00
IUUC-Obr-076451	Oryza brachyantha	36.14	1.00e-154	540.00
IUUC-Ogl-077535	Oryza glaberrima	35.50	2.00e-148	520.00
IUUC-Ogu-077995	Oryza glumaepatula	32.48	5.00e-121	429.00
IUUC-Oin-079431	Oryza indica	35.81	1.00e-150	527.00
IUUC-Olo-080495	Oryza longistaminata	32.30	2.00e-117	416.00
IUUC-Oni-082336	Oryza nivara	34.35	2.00e-138	486.00
IUUC-Opu-084028	Oryza punctata	34.09	3.00e-127	449.00
IUUC-Oru-084500	Oryza rufipogon	32.25	2.00e-118	420.00
IUUC-Osa-086242	Oryza sativa	35.70	2.00e-150	526.00
IUUC-Ola-086612	Oryzias latipes	55.75	0.00e+00	810.00
IUUC-Olu-087703	Ostreococcus lucimarinus	29.53	5.00e-107	382.00
IUUC-Oga-088572	Otolemur garnettii	92.75	0.00e+00	1659.00
IUUC-Oar-090363	Ovis aries	92.00	0.00e+00	1681.00
IUUC-Ptr-090477	Pan troglodytes	93.89	0.00e+00	1684.00
IUUC-Pan-092914	Papio anubis	94.20	0.00e+00	1711.00
IUUC-Psi-093019	Pelodiscus sinensis	73.36	0.00e+00	1321.00
IUUC-Pma-094303	Petromyzon marinus	50.99	0.00e+00	801.00
IUUC-Pno-094938	Phaeosphaeria nodorum	32.15	3.00e-98	353.00
IUUC-Ppa-095720	Physcomitrella patens	35.31	3.00e-152	532.00
IUUC-Pfo-097034	Poecilia formosa	55.99	0.00e+00	967.00
IUUC-Pab-097669	Pongo abelii	93.98	0.00e+00	1705.00
IUUC-Pop-098835	Populus trichocarpa	35.47	8.00e-151	527.00
IUUC-Pca-101097	Procavia capensis	85.05	7.00e-176	611.00
IUUC-Ppe-101430	Prunus persica	34.83	4.00e-152	532.00
IUUC-Pva-103152	Pteropus vampyrus	95.11	0.00e+00	1728.00
IUUC-Pgr-103517	Puccinia graminis	31.40	5.00e-124	439.00
IUUC-Ptt-103697	Puccinia triticina	33.07	2.00e-100	360.00
IUUC-Pte-104121	Pyrenophora teres	31.15	2.00e-105	377.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	31.55	1.00e-107	384.00
IUUC-Rno-105435	Rattus norvegicus	88.65	0.00e+00	1616.00
IUUC-Sce-106202	Saccharomyces cerevisiae	32.09	1.00e-111	397.00
IUUC-Sha-107272	Sarcophilus harrisii	81.24	0.00e+00	1369.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	36.31	5.00e-153	535.00
IUUC-Spo-108256	Schizosaccharomyces pombe	37.66	4.00e-152	532.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	31.17	4.00e-114	406.00
IUUC-Smo-108762	Selaginella moellendorffii	35.04	4.00e-152	532.00
IUUC-Sit-110051	Setaria italica	35.82	2.00e-148	519.00
IUUC-Sly-111181	Solanum lycopersicum	35.06	9.00e-155	540.00
IUUC-Stu-112018	Solanum tuberosum	34.95	5.00e-154	538.00
IUUC-Sar-113348	Sorex araneus	89.71	0.00e+00	1167.00
IUUC-Sbi-114282	Sorghum bicolor	35.96	2.00e-149	523.00
IUUC-Sre-114946	Sporisorium reilianum	33.26	3.00e-95	343.00
IUUC-Ssc-115287	Sus scrofa	94.12	0.00e+00	1705.00
IUUC-Tgu-117138	Taeniopygia guttata	69.62	0.00e+00	1093.00
IUUC-Tru-118232	Takifugu rubripes	58.52	0.00e+00	1000.00
IUUC-Tsy-119502	Tarsius syrichta	79.04	0.00e+00	1377.00
IUUC-Tni-120378	Tetraodon nigroviridis	57.05	0.00e+00	973.00
IUUC-Tca-121506	Theobroma cacao	35.84	7.00e-147	514.00
IUUC-Tre-122166	Trichoderma reesei	30.27	1.00e-105	377.00
IUUC-Tvi-122385	Trichoderma virens	30.33	2.00e-106	380.00
IUUC-Tae-122836	Triticum aestivum	35.31	1.00e-151	530.00
IUUC-Tur-126490	Triticum urartu	32.58	8.00e-114	405.00
IUUC-Tme-127157	Tuber melanosporum	33.67	4.00e-113	402.00
IUUC-Tbe-127981	Tupaia belangeri	85.11	0.00e+00	1422.00
IUUC-Ttr-128886	Tursiops truncatus	93.00	0.00e+00	1669.00
IUUC-Uma-129439	Ustilago maydis	32.35	9.00e-103	368.00
IUUC-Vda-129760	Verticillium dahliae	29.70	4.00e-104	372.00
IUUC-Vpa-130456	Vicugna pacos	94.33	0.00e+00	1706.00
IUUC-Vvi-131086	Vitis vinifera	34.46	2.00e-146	513.00
IUUC-Xtr-131829	Xenopus tropicalis	68.76	0.00e+00	1237.00
IUUC-Xma-133588	Xiphophorus maculatus	56.60	0.00e+00	951.00
IUUC-Yli-134328	Yarrowia lipolytica	30.80	2.00e-109	390.00
IUUC-Zma-135808	Zea mays	34.99	4.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence