iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117003

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

ABQF01006728

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000012534.1	ENSTGUT00000013053.1	ENSTGUP00000012905.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.80e-65	221.3	4	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           ++wl+Le++P++  ++++++g++ d+q+ ++y+++pe l+++++pv+++lllF+i+ek+e++r+++   + ++ +++d+ ++++f+kq+
   Q: 4    HRWLPLEANPDV-SQFLKQLGIHPDWQFVDVYGMEPELLSMVPRPVCAVLLLFPITEKYETFRTEE--EERIKAKGQDVKSSVYFMKQT 89
           58*********7.79************************************************766..5589***************** PP
   S: 95   igNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvs 182
           i+N+C+t++l+++++n+ dk+ ++  + l++++e + ++ pe++a+ l++ ++++++h+s a+++++++p+ +       +k  +hf++
   Q: 90   INNACGTIGLIHAIANNRDKMnFETNSSLKKFLEDSLSMTPEERAKYLETYEAIRVTHESSAHEGQTEAPSID-------EKVDLHFIA 171
           **********************************************************************888.......8899***** PP
   S: 183  yvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           +vn++g+lyeldg+kpfP+++g+++++  l+d+++v+++f+er    + +e+rfn++a++a+
   Q: 172  LVNVGGHLYELDGRKPFPINHGETSDDSFLEDAIEVCKKFMER----DPEELRFNAIALSAA 229
           *******************************************....9**********9875 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MEPHRWLPLE ANPDVSQFLK QLGIHPDWQF VDVYGMEPEL LSMVPRPVCA VLLLFPITEK 60
YETFRTEEEE RIKAKGQDVK SSVYFMKQTI NNACGTIGLI HAIANNRDKM NFETNSSLKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGGGTC AGGGTGAGGC GCGGCGGCAC CGTGAGGCGC TGTCAGAGCC CGCCGGGAGG 60
GTCCGCCCAG CTCCGCGCCG GGATCCGCCG CCGCTGCCAT GGAGCCGCAT CGCTGGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	40.60	2.00e-45	175.00
IUUC-Aml-001344	Ailuropoda melanoleuca	86.09	8.00e-114	402.00
IUUC-Atr-002931	Amborella trichopoda	45.75	5.00e-45	173.00
IUUC-Apl-003949	Anas platyrhynchos	100.00	3.00e-116	410.00
IUUC-Aca-004924	Anolis carolinensis	87.01	2.00e-115	407.00
IUUC-Aly-005939	Arabidopsis lyrata	50.67	1.00e-52	198.00
IUUC-Ath-006827	Arabidopsis thaliana	50.67	1.00e-53	202.00
IUUC-Ago-007950	Ashbya gossypii	33.92	1.00e-26	112.00
IUUC-Acl-008305	Aspergillus clavatus	36.32	6.00e-34	137.00
IUUC-Afl-008611	Aspergillus flavus	38.20	8.00e-38	149.00
IUUC-Afu-008945	Aspergillus fumigatus	38.20	3.00e-36	144.00
IUUC-Ani-009339	Aspergillus nidulans	37.61	4.00e-37	147.00
IUUC-Ang-009691	Aspergillus niger	36.05	1.00e-35	142.00
IUUC-Aor-009961	Aspergillus oryzae	38.20	9.00e-38	149.00
IUUC-Ate-010316	Aspergillus terreus	38.03	8.00e-38	149.00
IUUC-Ame-011157	Astyanax mexicanus	73.91	1.00e-96	345.00
IUUC-Bgr-012125	Blumeria graminis	33.76	4.00e-33	134.00
IUUC-Bta-012673	Bos taurus	85.65	6.00e-113	399.00
IUUC-Bci-013734	Botrytis cinerea	37.50	7.00e-36	143.00
IUUC-Bdi-014330	Brachypodium distachyon	43.56	3.00e-49	188.00
IUUC-Bol-015214	Brassica oleracea	50.22	4.00e-54	203.00
IUUC-Bra-017491	Brassica rapa	50.67	8.00e-54	202.00
IUUC-Cel-018302	Caenorhabditis elegans	36.49	4.00e-29	120.00
IUUC-Cfa-020371	Canis familiaris	84.21	2.00e-89	320.00
IUUC-Cpo-022036	Cavia porcellus	83.91	2.00e-109	387.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	42.99	1.00e-31	129.00
IUUC-Csa-023854	Chlorocebus sabaeus	85.22	4.00e-112	396.00
IUUC-Cin-025545	Ciona intestinalis	48.67	2.00e-63	234.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	30.90	8.00e-26	110.00
IUUC-Cne-026914	Cryptococcus neoformans	37.02	4.00e-31	127.00
IUUC-Cme-027216	Cyanidioschyzon merolae	38.29	1.00e-28	119.00
IUUC-Dre-028356	Danio rerio	73.48	7.00e-96	342.00
IUUC-Dse-031461	Dothistroma septosporum	37.29	7.00e-31	126.00
IUUC-Dme-032146	Drosophila melanogaster	49.78	5.00e-57	213.00
IUUC-Eca-033220	Equus caballus	85.65	9.00e-113	398.00
IUUC-Fca-036421	Felis catus	86.09	8.00e-114	402.00
IUUC-Fal-036773	Ficedula albicollis	99.07	8.00e-116	409.00
IUUC-Fox-037830	Fusarium oxysporum	35.90	2.00e-36	145.00
IUUC-Fso-038259	Fusarium solani	34.50	5.00e-32	132.00
IUUC-Gmo-039468	Gadus morhua	69.43	3.00e-81	293.00
IUUC-Ggr-039832	Gaeumannomyces graminis	35.37	4.00e-31	127.00
IUUC-Gga-041205	Gallus gallus	99.13	9.00e-125	438.00
IUUC-Gac-041629	Gasterosteus aculeatus	69.30	6.00e-87	312.00
IUUC-Gma-043057	Glycine max	47.11	1.00e-44	172.00
IUUC-Ggo-044533	Gorilla gorilla	85.71	9.00e-114	402.00
IUUC-Hsa-046754	Homo sapiens	86.09	8.00e-114	402.00
IUUC-Hvu-047176	Hordeum vulgare	38.77	6.00e-39	153.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	84.18	2.00e-73	267.00
IUUC-Kpa-049123	Komagataella pastoris	35.29	7.00e-27	113.00
IUUC-Lch-049685	Latimeria chalumnae	76.75	2.00e-102	363.00
IUUC-Lpe-051377	Leersia perrieri	42.79	4.00e-41	160.00
IUUC-Loc-051988	Lepisosteus oculatus	76.09	6.00e-101	359.00
IUUC-Lma-053316	Leptosphaeria maculans	40.69	2.00e-39	155.00
IUUC-Laf-053985	Loxodonta africana	84.42	2.00e-112	397.00
IUUC-Mcc-055888	Macaca mulatta	85.15	1.00e-111	394.00
IUUC-Mor-057271	Magnaporthe oryzae	36.80	3.00e-36	144.00
IUUC-Mpo-057343	Magnaporthe poae	30.47	1.00e-18	85.50
IUUC-Mtr-057713	Medicago truncatula	43.11	3.00e-45	174.00
IUUC-Mla-058942	Melampsora laricipopulina	45.37	5.00e-41	160.00
IUUC-Mga-059702	Meleagris gallopavo	99.53	1.00e-115	408.00
IUUC-Mvi-060249	Microbotryum violaceum	41.67	7.00e-37	146.00
IUUC-Mmr-061284	Microcebus murinus	83.54	3.00e-72	264.00
IUUC-Mdo-062639	Monodelphis domestica	75.75	8.00e-111	392.00
IUUC-Mmu-063299	Mus musculus	86.09	1.00e-113	401.00
IUUC-Mac-065075	Musa acuminata	46.32	3.00e-49	187.00
IUUC-Mpu-066769	Mustela putorius furo	86.09	8.00e-114	402.00
IUUC-Mlu-066937	Myotis lucifugus	85.65	2.00e-113	400.00
IUUC-Nfi-068320	Neosartorya fischeri	38.63	3.00e-37	148.00
IUUC-Ncr-068673	Neurospora crassa	37.66	4.00e-39	154.00
IUUC-Nle-069175	Nomascus leucogenys	86.92	6.00e-106	376.00
IUUC-Opr-070652	Ochotona princeps	84.35	6.00e-50	190.00
IUUC-Ont-072170	Oreochromis niloticus	71.49	2.00e-89	320.00
IUUC-Oan-073247	Ornithorhynchus anatinus	85.71	1.00e-48	183.00
IUUC-Ocu-074422	Oryctolagus cuniculus	85.65	3.00e-113	400.00
IUUC-Oba-075098	Oryza barthii	40.62	3.00e-44	171.00
IUUC-Obr-076041	Oryza brachyantha	42.48	3.00e-48	184.00
IUUC-Ogl-076980	Oryza glaberrima	42.92	1.00e-47	182.00
IUUC-Ogu-078978	Oryza glumaepatula	36.65	3.00e-41	160.00
IUUC-Oin-079285	Oryza indica	40.18	2.00e-43	168.00
IUUC-Olo-080671	Oryza longistaminata	41.07	3.00e-44	171.00
IUUC-Ome-081428	Oryza meridionalis	40.18	6.00e-43	166.00
IUUC-Oni-082406	Oryza nivara	40.62	3.00e-44	171.00
IUUC-Opu-083305	Oryza punctata	41.07	1.00e-43	168.00
IUUC-Oru-084969	Oryza rufipogon	40.62	3.00e-44	171.00
IUUC-Osa-085830	Oryza sativa	42.92	1.00e-47	182.00
IUUC-Ola-086893	Oryzias latipes	69.30	6.00e-85	306.00
IUUC-Olu-087858	Ostreococcus lucimarinus	42.54	4.00e-46	177.00
IUUC-Oga-088055	Otolemur garnettii	85.71	9.00e-114	402.00
IUUC-Oar-090319	Ovis aries	85.65	5.00e-113	399.00
IUUC-Pan-092714	Papio anubis	84.85	2.00e-112	397.00
IUUC-Psi-094036	Pelodiscus sinensis	92.56	2.00e-111	394.00
IUUC-Pma-094412	Petromyzon marinus	65.58	5.00e-53	199.00
IUUC-Pno-094997	Phaeosphaeria nodorum	35.97	2.00e-27	115.00
IUUC-Ppa-095519	Physcomitrella patens	49.55	2.00e-59	221.00
IUUC-Pfo-096182	Poecilia formosa	68.70	7.00e-87	312.00
IUUC-Pab-098216	Pongo abelii	86.81	1.00e-73	267.00
IUUC-Pop-099282	Populus trichocarpa	46.22	6.00e-46	176.00
IUUC-Ppe-101332	Prunus persica	46.67	3.00e-51	194.00
IUUC-Pgr-103430	Puccinia graminis	45.38	3.00e-45	174.00
IUUC-Ptt-103955	Puccinia triticina	47.84	2.00e-46	178.00
IUUC-Pte-104414	Pyrenophora teres	37.77	5.00e-34	137.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	32.50	5.00e-28	117.00
IUUC-Rno-105096	Rattus norvegicus	84.78	2.00e-112	397.00
IUUC-Sce-106412	Saccharomyces cerevisiae	32.63	5.00e-25	107.00
IUUC-Sha-106677	Sarcophilus harrisii	84.65	3.00e-109	387.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	29.52	1.00e-20	92.40
IUUC-Spo-108322	Schizosaccharomyces pombe	33.18	2.00e-24	104.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	36.75	3.00e-34	138.00
IUUC-Smo-109283	Selaginella moellendorffii	46.75	2.00e-48	184.00
IUUC-Sit-110163	Setaria italica	44.25	1.00e-48	185.00
IUUC-Sly-111613	Solanum lycopersicum	48.89	1.00e-55	208.00
IUUC-Stu-112526	Solanum tuberosum	48.44	3.00e-50	190.00
IUUC-Sbi-114545	Sorghum bicolor	43.17	1.00e-46	178.00
IUUC-Sre-114961	Sporisorium reilianum	39.06	2.00e-32	132.00
IUUC-Ssc-115255	Sus scrofa	85.85	8.00e-105	372.00
IUUC-Tru-118330	Takifugu rubripes	64.48	2.00e-64	239.00
IUUC-Tni-120042	Tetraodon nigroviridis	65.76	2.00e-66	246.00
IUUC-Tca-120976	Theobroma cacao	48.00	5.00e-53	200.00
IUUC-Tre-122149	Trichoderma reesei	38.26	3.00e-38	151.00
IUUC-Tvi-122450	Trichoderma virens	38.96	5.00e-38	150.00
IUUC-Tae-122693	Triticum aestivum	41.99	2.00e-46	179.00
IUUC-Tur-126250	Triticum urartu	40.60	4.00e-45	174.00
IUUC-Tme-126961	Tuber melanosporum	36.64	4.00e-32	130.00
IUUC-Uma-129382	Ustilago maydis	39.66	7.00e-37	146.00
IUUC-Vda-129850	Verticillium dahliae	31.93	4.00e-28	117.00
IUUC-Vpa-130783	Vicugna pacos	84.35	1.00e-49	189.00
IUUC-Vvi-131661	Vitis vinifera	44.44	2.00e-49	187.00
IUUC-Xtr-132428	Xenopus tropicalis	70.87	2.00e-96	344.00
IUUC-Xma-134245	Xiphophorus maculatus	67.98	1.00e-86	311.00
IUUC-Yli-134570	Yarrowia lipolytica	37.93	2.00e-33	135.00
IUUC-Zma-134740	Zea mays	42.73	2.00e-48	184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence