iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013336

Ensembl Protein ID

ENSBTAP00000019966.5

UniProt Accession

E1BK25; E1BK25_BOVIN

Genbank Protein ID

ENSBTAP00000019966

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02046954

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000014996.5	ENSBTAT00000019966.5	ENSBTAP00000019966.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-27	95.0	153	191
UBD/Beta-Prp	8.80e-55	186.1	497	751

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvl 35
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ l
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDIL 191
           89**********888*****9989*********988765 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsvls 99
           ++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+++
   Q: 497  VMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSITA 585
           5899******************************************99888899****************97888999*********** PP
   S: 100  lsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltg 177
           ++f  ++   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g
   Q: 586  IKFTGNRdIQMISCGADKSIYF---RSAQRASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTmngKQKKCYKGSQG 671
           *****885789*******9976...444444444444332112222233446777788****************988888889999898 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dl 251
            +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW       ++
   Q: 672  -DDGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitNC 751
           .999999999**************************************************************554444433 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAALGPGGYA RNDTVEKLPS VMAGVPARRA QSSPPPAPPL CLRRRTRLPA APEDTVQNRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILNPKE NKQQHILNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGGCGGCT GCGGCGGTTG AGAAGTGTAA CGGTCGCCGG GCTCCGACGC GACGATGGCG 60
GCCTTGGGGC CCGGAGGCTA CGCGCGGAAT GATACAGTTG AGAAGCTGCC ATCAGTCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR003143--Cyt_cd1_C
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005813--C:centrosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	81.80	0.00e+00	2350.00
IUUC-Aca-004935	Anolis carolinensis	71.15	0.00e+00	1004.00
IUUC-Ath-007624	Arabidopsis thaliana	30.51	5.00e-93	336.00
IUUC-Afu-008757	Aspergillus fumigatus	22.53	2.00e-29	124.00
IUUC-Cel-018592	Caenorhabditis elegans	28.67	1.00e-72	269.00
IUUC-Cja-019094	Callithrix jacchus	78.03	0.00e+00	2178.00
IUUC-Cfa-020529	Canis familiaris	80.90	0.00e+00	2348.00
IUUC-Cpo-021970	Cavia porcellus	86.16	0.00e+00	1646.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	35.11	3.00e-13	70.90
IUUC-Csa-024161	Chlorocebus sabaeus	78.16	0.00e+00	2190.00
IUUC-Cho-024310	Choloepus hoffmanni	84.95	0.00e+00	1170.00
IUUC-Cin-025412	Ciona intestinalis	53.48	2.00e-59	221.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.91	2.00e-26	114.00
IUUC-Dno-029933	Dasypus novemcinctus	74.86	0.00e+00	2049.00
IUUC-Dor-031147	Dipodomys ordii	75.59	0.00e+00	2043.00
IUUC-Dse-031501	Dothistroma septosporum	30.53	4.00e-23	103.00
IUUC-Eca-033675	Equus caballus	81.07	0.00e+00	2268.00
IUUC-Fca-035826	Felis catus	82.30	0.00e+00	2414.00
IUUC-Gma-043644	Glycine max	32.35	3.00e-103	370.00
IUUC-Ggo-045152	Gorilla gorilla	79.46	0.00e+00	2187.00
IUUC-Hsa-045891	Homo sapiens	79.53	0.00e+00	2197.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	92.76	0.00e+00	1557.00
IUUC-Lch-049669	Latimeria chalumnae	58.49	0.00e+00	1006.00
IUUC-Loc-052488	Lepisosteus oculatus	60.41	0.00e+00	1032.00
IUUC-Laf-053992	Loxodonta africana	77.18	0.00e+00	2168.00
IUUC-Mcc-054994	Macaca mulatta	78.67	0.00e+00	2158.00
IUUC-Meu-056815	Macropus eugenii	80.42	0.00e+00	1413.00
IUUC-Mtr-058383	Medicago truncatula	31.11	5.00e-52	198.00
IUUC-Mmr-060693	Microcebus murinus	77.47	0.00e+00	2131.00
IUUC-Mdo-063007	Monodelphis domestica	62.32	0.00e+00	1736.00
IUUC-Mmu-064067	Mus musculus	73.60	0.00e+00	2053.00
IUUC-Mpu-066532	Mustela putorius furo	81.89	0.00e+00	2379.00
IUUC-Mlu-066982	Myotis lucifugus	81.25	0.00e+00	2241.00
IUUC-Nle-070042	Nomascus leucogenys	83.24	0.00e+00	1875.00
IUUC-Opr-070397	Ochotona princeps	77.32	0.00e+00	2197.00
IUUC-Oan-073119	Ornithorhynchus anatinus	66.96	0.00e+00	870.00
IUUC-Ocu-074274	Oryctolagus cuniculus	77.60	0.00e+00	2142.00
IUUC-Oga-088577	Otolemur garnettii	79.03	0.00e+00	2242.00
IUUC-Oar-090117	Ovis aries	93.36	0.00e+00	2668.00
IUUC-Ptr-090553	Pan troglodytes	79.33	0.00e+00	2213.00
IUUC-Pan-092559	Papio anubis	67.56	0.00e+00	991.00
IUUC-Psi-093710	Pelodiscus sinensis	65.31	0.00e+00	1405.00
IUUC-Pab-098510	Pongo abelii	79.21	0.00e+00	2153.00
IUUC-Pop-099155	Populus trichocarpa	31.95	4.00e-100	359.00
IUUC-Pca-100323	Procavia capensis	71.12	0.00e+00	1332.00
IUUC-Pva-102895	Pteropus vampyrus	81.87	0.00e+00	2322.00
IUUC-Rno-105598	Rattus norvegicus	73.92	0.00e+00	2087.00
IUUC-Sha-107013	Sarcophilus harrisii	65.76	0.00e+00	1781.00
IUUC-Smo-109134	Selaginella moellendorffii	37.34	6.00e-136	479.00
IUUC-Sar-113261	Sorex araneus	74.84	0.00e+00	2107.00
IUUC-Ssc-115317	Sus scrofa	83.28	0.00e+00	2319.00
IUUC-Tsy-118799	Tarsius syrichta	90.15	0.00e+00	853.00
IUUC-Tre-122008	Trichoderma reesei	23.27	9.00e-31	129.00
IUUC-Tvi-122281	Trichoderma virens	23.67	2.00e-30	128.00
IUUC-Tme-127128	Tuber melanosporum	24.32	1.00e-31	132.00
IUUC-Tbe-127555	Tupaia belangeri	94.15	0.00e+00	1023.00
IUUC-Ttr-128722	Tursiops truncatus	83.59	0.00e+00	2363.00
IUUC-Vda-129957	Verticillium dahliae	23.49	1.00e-30	128.00
IUUC-Vpa-130392	Vicugna pacos	62.74	5.00e-174	604.00
IUUC-Vvi-131035	Vitis vinifera	33.94	6.00e-109	388.00
IUUC-Xtr-131789	Xenopus tropicalis	59.76	0.00e+00	996.00
IUUC-Yli-134437	Yarrowia lipolytica	26.05	4.00e-16	80.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence