iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000012353.3	ENSMMUT00000017318.3	ENSMMUP00000016220.3
ENSMMUG00000012353.3	ENSMMUT00000041204.2	ENSMMUP00000034240.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.30e-06	28.2	634	675

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++  +d    lpC H+fh+ C+  w       +k+ +CP+Cr
   Q: 634  CPICCSEYikDDIATELPCHHFFHKPCVSIW------LQKSGTCPVCR 675
           ******99753324449**************......**********8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSQYTEKEPA AMDQESGKAA WPKPAGGYQT ITGRRYGRRH AYVSFKPCMT RHERSLGRAG 60
DDYEVLELDD VPKENSSGSS PLDQVDSSLP SEPIFEKSET EIPTCGSALN QTTESSQSFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCACAAT ACACTGAAAA GGAGCCAGCA GGTAAGGAAA GTCAGTTCTA CATTGAGCAC 60
TTCTTGTTTC TCCCTCTGGG TACCTTGAGT ACCAGTAAGT GACATGTGAT CATCTGACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR030639--Praja-2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0045111--C:intermediate filament cytoskeleton
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035329--P:hippo signaling
GO:0010738--P:regulation of protein kinase A signaling

KEGG

mcc:705109

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001388	Ailuropoda melanoleuca	86.66	0.00e+00	1212.00
IUUC-Aca-004858	Anolis carolinensis	47.73	8.00e-153	534.00
IUUC-Ago-007872	Ashbya gossypii	41.54	5.00e-09	53.50
IUUC-Ame-010842	Astyanax mexicanus	59.61	4.00e-62	232.00
IUUC-Bta-013122	Bos taurus	84.79	0.00e+00	1193.00
IUUC-Cja-019345	Callithrix jacchus	93.25	0.00e+00	1009.00
IUUC-Cfa-021193	Canis familiaris	88.69	0.00e+00	1198.00
IUUC-Cpo-021991	Cavia porcellus	82.02	0.00e+00	1120.00
IUUC-Csa-024052	Chlorocebus sabaeus	98.65	0.00e+00	1325.00
IUUC-Cho-024680	Choloepus hoffmanni	86.06	0.00e+00	1198.00
IUUC-Dre-027662	Danio rerio	45.25	2.00e-62	233.00
IUUC-Dno-028851	Dasypus novemcinctus	87.29	0.00e+00	1207.00
IUUC-Dor-031005	Dipodomys ordii	83.04	0.00e+00	944.00
IUUC-Ete-032637	Echinops telfairi	71.77	3.00e-139	488.00
IUUC-Eca-034011	Equus caballus	90.36	0.00e+00	1039.00
IUUC-Eeu-034596	Erinaceus europaeus	82.46	0.00e+00	1078.00
IUUC-Fca-036523	Felis catus	89.12	0.00e+00	1184.00
IUUC-Fal-037255	Ficedula albicollis	43.27	7.00e-119	421.00
IUUC-Gga-040434	Gallus gallus	46.97	2.00e-137	482.00
IUUC-Hsa-046514	Homo sapiens	96.90	0.00e+00	1318.00
IUUC-Itr-047883	Ictidomys tridecemlineatus	87.37	0.00e+00	1168.00
IUUC-Lch-050133	Latimeria chalumnae	33.94	2.00e-51	196.00
IUUC-Loc-051901	Lepisosteus oculatus	41.14	3.00e-112	399.00
IUUC-Laf-054289	Loxodonta africana	86.61	0.00e+00	1168.00
IUUC-Meu-056394	Macropus eugenii	76.92	7.00e-108	384.00
IUUC-Mga-059679	Meleagris gallopavo	34.10	1.00e-21	96.30
IUUC-Mmr-060712	Microcebus murinus	88.21	0.00e+00	1159.00
IUUC-Mdo-062457	Monodelphis domestica	57.58	0.00e+00	733.00
IUUC-Mmu-063933	Mus musculus	83.85	0.00e+00	1117.00
IUUC-Mpu-065994	Mustela putorius furo	89.78	0.00e+00	1232.00
IUUC-Mlu-067843	Myotis lucifugus	85.75	0.00e+00	1162.00
IUUC-Nle-069787	Nomascus leucogenys	96.46	0.00e+00	1310.00
IUUC-Opr-071190	Ochotona princeps	71.09	2.00e-133	469.00
IUUC-Oan-072728	Ornithorhynchus anatinus	32.43	2.00e-64	240.00
IUUC-Ocu-074152	Oryctolagus cuniculus	87.91	0.00e+00	1146.00
IUUC-Oga-088608	Otolemur garnettii	87.75	0.00e+00	1175.00
IUUC-Oar-090415	Ovis aries	81.96	0.00e+00	1107.00
IUUC-Ptr-091211	Pan troglodytes	96.76	0.00e+00	1313.00
IUUC-Pan-091698	Papio anubis	91.67	0.00e+00	1221.00
IUUC-Psi-093139	Pelodiscus sinensis	52.05	1.00e-152	533.00
IUUC-Pab-097745	Pongo abelii	96.31	0.00e+00	1311.00
IUUC-Pca-100681	Procavia capensis	79.71	0.00e+00	1034.00
IUUC-Pva-102525	Pteropus vampyrus	89.14	0.00e+00	1234.00
IUUC-Rno-105620	Rattus norvegicus	82.14	0.00e+00	1120.00
IUUC-Sce-106223	Saccharomyces cerevisiae	48.89	8.00e-09	53.10
IUUC-Sha-106812	Sarcophilus harrisii	54.03	2.00e-137	482.00
IUUC-Sar-113270	Sorex araneus	88.18	5.00e-167	581.00
IUUC-Ssc-115913	Sus scrofa	83.22	0.00e+00	730.00
IUUC-Tgu-117101	Taeniopygia guttata	52.61	9.00e-67	246.00
IUUC-Tsy-119078	Tarsius syrichta	88.98	0.00e+00	1011.00
IUUC-Tbe-127715	Tupaia belangeri	81.13	0.00e+00	1086.00
IUUC-Ttr-129003	Tursiops truncatus	89.44	0.00e+00	1261.00
IUUC-Vpa-130373	Vicugna pacos	91.12	0.00e+00	1238.00
IUUC-Vvi-131189	Vitis vinifera	46.05	3.00e-13	68.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence