iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068181

Ensembl Protein ID

ENSMLUP00000006456.2

UniProt Accession

G1P8F6; G1P8F6_MYOLU

Genbank Protein ID

ENSMLUP00000006456

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02007437

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007043.2	ENSMLUT00000007068.2	ENSMLUP00000006456.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	90.97	0.00e+00	2400.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

TLRRASGAAT EAPRRGEAPP GSGVPSGERA SERRRRRGAE GTTRDGSCLA RRARSSPELW 60
LPRRSGCAGD AAAAARPGKM SAEAGEGITF SVPPLAHSGL CALAEDGSCW RGGAAAVAEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCTGCGGC GGGCGAGCGG CGCGGCCACG GAGGCGCCGA GGAGGGGCGA GGCGCCGCCG 60
GGCAGCGGCG TCCCTTCGGG GGAAAGGGCG TCCGAGAGGA GGCGTCGGCG CGGCGCGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	91.97	0.00e+00	2248.00
IUUC-Apl-003713	Anas platyrhynchos	86.92	0.00e+00	2020.00
IUUC-Aca-005331	Anolis carolinensis	86.74	0.00e+00	2049.00
IUUC-Ame-011158	Astyanax mexicanus	75.28	0.00e+00	1806.00
IUUC-Bta-012770	Bos taurus	90.97	0.00e+00	2357.00
IUUC-Cja-019656	Callithrix jacchus	90.74	0.00e+00	2385.00
IUUC-Cfa-020488	Canis familiaris	91.11	0.00e+00	2348.00
IUUC-Cpo-022516	Cavia porcellus	89.66	0.00e+00	2220.00
IUUC-Csa-023104	Chlorocebus sabaeus	94.17	0.00e+00	2226.00
IUUC-Cho-024379	Choloepus hoffmanni	88.38	0.00e+00	1210.00
IUUC-Dre-028836	Danio rerio	73.92	0.00e+00	1839.00
IUUC-Dno-029842	Dasypus novemcinctus	91.45	0.00e+00	2128.00
IUUC-Dor-030990	Dipodomys ordii	93.25	0.00e+00	1885.00
IUUC-Ete-032693	Echinops telfairi	80.41	0.00e+00	1890.00
IUUC-Eca-033337	Equus caballus	93.08	0.00e+00	2244.00
IUUC-Eeu-034602	Erinaceus europaeus	77.06	0.00e+00	1946.00
IUUC-Fca-035954	Felis catus	94.29	0.00e+00	1883.00
IUUC-Fal-037358	Ficedula albicollis	86.76	0.00e+00	2049.00
IUUC-Gmo-038836	Gadus morhua	77.11	0.00e+00	1722.00
IUUC-Gga-040443	Gallus gallus	86.24	0.00e+00	2154.00
IUUC-Gac-041634	Gasterosteus aculeatus	76.13	0.00e+00	1890.00
IUUC-Ggo-045263	Gorilla gorilla	89.18	0.00e+00	2312.00
IUUC-Hsa-046906	Homo sapiens	91.04	0.00e+00	2390.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	92.27	0.00e+00	1064.00
IUUC-Lch-050213	Latimeria chalumnae	77.52	0.00e+00	1766.00
IUUC-Loc-051829	Lepisosteus oculatus	74.92	0.00e+00	1824.00
IUUC-Laf-053538	Loxodonta africana	90.60	0.00e+00	2376.00
IUUC-Mcc-054776	Macaca mulatta	90.97	0.00e+00	2412.00
IUUC-Mga-059636	Meleagris gallopavo	86.48	0.00e+00	2076.00
IUUC-Mmr-061323	Microcebus murinus	90.76	0.00e+00	2326.00
IUUC-Mdo-062146	Monodelphis domestica	86.39	0.00e+00	2207.00
IUUC-Mmu-064022	Mus musculus	88.83	0.00e+00	2304.00
IUUC-Mpu-066531	Mustela putorius furo	88.48	0.00e+00	2361.00
IUUC-Nle-069758	Nomascus leucogenys	94.09	0.00e+00	2227.00
IUUC-Opr-070531	Ochotona princeps	86.29	0.00e+00	1430.00
IUUC-Ont-072014	Oreochromis niloticus	76.95	0.00e+00	1866.00
IUUC-Oan-073169	Ornithorhynchus anatinus	91.36	0.00e+00	2181.00
IUUC-Ocu-074050	Oryctolagus cuniculus	89.62	0.00e+00	2089.00
IUUC-Ola-086941	Oryzias latipes	80.26	0.00e+00	1516.00
IUUC-Oga-088796	Otolemur garnettii	89.88	0.00e+00	2318.00
IUUC-Oar-090445	Ovis aries	94.85	0.00e+00	2240.00
IUUC-Ptr-090846	Pan troglodytes	90.75	0.00e+00	2405.00
IUUC-Pan-091986	Papio anubis	91.04	0.00e+00	2414.00
IUUC-Psi-093805	Pelodiscus sinensis	86.78	0.00e+00	2169.00
IUUC-Pfo-097301	Poecilia formosa	76.58	0.00e+00	1881.00
IUUC-Pab-097662	Pongo abelii	91.56	0.00e+00	2342.00
IUUC-Pca-100755	Procavia capensis	90.31	0.00e+00	688.00
IUUC-Pva-102280	Pteropus vampyrus	83.61	0.00e+00	2156.00
IUUC-Rno-105547	Rattus norvegicus	87.60	0.00e+00	2293.00
IUUC-Sha-106859	Sarcophilus harrisii	91.16	0.00e+00	2171.00
IUUC-Sar-113714	Sorex araneus	81.98	0.00e+00	1870.00
IUUC-Tgu-117116	Taeniopygia guttata	85.09	0.00e+00	2098.00
IUUC-Tru-118088	Takifugu rubripes	75.81	0.00e+00	1893.00
IUUC-Tsy-119616	Tarsius syrichta	85.77	0.00e+00	1899.00
IUUC-Tni-120284	Tetraodon nigroviridis	75.22	0.00e+00	1854.00
IUUC-Tbe-127900	Tupaia belangeri	94.24	0.00e+00	841.00
IUUC-Ttr-128294	Tursiops truncatus	81.04	0.00e+00	2014.00
IUUC-Vpa-130470	Vicugna pacos	85.42	0.00e+00	2002.00
IUUC-Xtr-132396	Xenopus tropicalis	73.64	0.00e+00	1926.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence