iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066161

Ensembl Protein ID

ENSMPUP00000001274.1

UniProt Accession

M3XQC4; M3XQC4_MUSPF

Genbank Protein ID

ENSMPUP00000001274

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01092969

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000001285.1	ENSMPUT00000001301.1	ENSMPUP00000001274.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-118	396.2	65	394

Active Site

Position(s)	Description	Evidence
365	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s++ np+hl++F+f+G++lg+al +++l+++ 
   Q: 65   AKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIVNPDYALFTQSA-DGTTFQPNSNSYV-NPDHLNYFRFAGQILGLALNHRQLVNIY 150
           679999*************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG +i Vt++Nk eYv+lv+e+
   Q: 151  FTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTEL 236
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf+  ip++l++lF+e elell++G++eidv+d+ ++t+y++gy++++p+iqwFwev+e+++ eer  +LqFvT
   Q: 237  RMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIRNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVT 325
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa+++     + f+i     +++ lP+s+TC+n+LkLPeY+skeilk++Ll+A + +  g
   Q: 326  GSSRVPHGGFANIMggsgLQNFTIAAvPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGsYG 394
           ******************8888888868888********************************986555 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSRFMHIIKA QPFKDRCEWF YEHLHSGQPD SDMVHRPVNE NDILLVHRDS IFRSSCEVVS 60
KANCAKLKQG IAVRFHGEEG MGQGVVREWF DILSNEIVNP DYALFTQSAD GTTFQPNSNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTTGCTTT TCACAGGAAG AATAGAACTC ATTCTTCCTG TCCATTTAAA CAAATTATAT 60
TTTTCTTTCA GAAATCCCAA AATTATATTT GACCACTTTC ACTTTCTCCT TGAATGTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001490	Ailuropoda melanoleuca	99.75	0.00e+00	833.00
IUUC-Apl-003400	Anas platyrhynchos	96.23	0.00e+00	804.00
IUUC-Aca-005375	Anolis carolinensis	94.97	0.00e+00	798.00
IUUC-Ame-011847	Astyanax mexicanus	91.96	0.00e+00	769.00
IUUC-Bta-012831	Bos taurus	99.50	0.00e+00	832.00
IUUC-Cja-019160	Callithrix jacchus	99.25	0.00e+00	829.00
IUUC-Cfa-020346	Canis familiaris	99.75	0.00e+00	834.00
IUUC-Cpo-021766	Cavia porcellus	98.49	0.00e+00	827.00
IUUC-Csa-023768	Chlorocebus sabaeus	99.25	0.00e+00	832.00
IUUC-Cho-024688	Choloepus hoffmanni	99.25	0.00e+00	828.00
IUUC-Cin-025417	Ciona intestinalis	53.40	3.00e-122	432.00
IUUC-Csv-025993	Ciona savignyi	52.01	1.00e-117	417.00
IUUC-Dre-027819	Danio rerio	90.70	0.00e+00	765.00
IUUC-Dno-029027	Dasypus novemcinctus	99.00	0.00e+00	827.00
IUUC-Dor-030327	Dipodomys ordii	93.97	0.00e+00	766.00
IUUC-Ete-032966	Echinops telfairi	99.25	0.00e+00	832.00
IUUC-Eca-034339	Equus caballus	99.25	0.00e+00	832.00
IUUC-Eeu-034544	Erinaceus europaeus	82.02	3.00e-148	519.00
IUUC-Fca-035617	Felis catus	100.00	0.00e+00	833.00
IUUC-Fal-036687	Ficedula albicollis	95.73	0.00e+00	807.00
IUUC-Gmo-039508	Gadus morhua	86.93	0.00e+00	737.00
IUUC-Gga-040845	Gallus gallus	96.23	0.00e+00	809.00
IUUC-Gac-041894	Gasterosteus aculeatus	89.95	0.00e+00	759.00
IUUC-Ggo-044465	Gorilla gorilla	99.25	0.00e+00	828.00
IUUC-Hsa-045731	Homo sapiens	99.50	0.00e+00	834.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	99.25	0.00e+00	832.00
IUUC-Lch-050436	Latimeria chalumnae	93.22	0.00e+00	784.00
IUUC-Loc-052287	Lepisosteus oculatus	92.71	0.00e+00	780.00
IUUC-Laf-053846	Loxodonta africana	99.50	0.00e+00	833.00
IUUC-Mcc-055845	Macaca mulatta	99.50	0.00e+00	834.00
IUUC-Meu-056060	Macropus eugenii	75.26	2.00e-121	430.00
IUUC-Mga-059935	Meleagris gallopavo	96.23	0.00e+00	808.00
IUUC-Mmr-060960	Microcebus murinus	99.50	0.00e+00	833.00
IUUC-Mdo-061851	Monodelphis domestica	97.99	0.00e+00	823.00
IUUC-Mmu-063657	Mus musculus	98.74	0.00e+00	828.00
IUUC-Mlu-067354	Myotis lucifugus	98.25	0.00e+00	796.00
IUUC-Nle-069112	Nomascus leucogenys	99.50	0.00e+00	834.00
IUUC-Opr-070686	Ochotona princeps	87.94	0.00e+00	718.00
IUUC-Ont-072398	Oreochromis niloticus	89.70	0.00e+00	755.00
IUUC-Oan-073194	Ornithorhynchus anatinus	97.74	0.00e+00	821.00
IUUC-Ocu-074397	Oryctolagus cuniculus	97.72	0.00e+00	813.00
IUUC-Ola-086777	Oryzias latipes	87.94	0.00e+00	743.00
IUUC-Oga-088684	Otolemur garnettii	99.25	0.00e+00	828.00
IUUC-Oar-089428	Ovis aries	97.92	0.00e+00	792.00
IUUC-Ptr-090529	Pan troglodytes	99.25	0.00e+00	832.00
IUUC-Pan-091702	Papio anubis	99.50	0.00e+00	834.00
IUUC-Psi-093969	Pelodiscus sinensis	97.49	0.00e+00	820.00
IUUC-Pfo-097364	Poecilia formosa	90.95	0.00e+00	766.00
IUUC-Pab-098574	Pongo abelii	99.50	0.00e+00	834.00
IUUC-Pca-100525	Procavia capensis	69.35	4.00e-152	531.00
IUUC-Pva-102365	Pteropus vampyrus	99.49	0.00e+00	824.00
IUUC-Rno-105153	Rattus norvegicus	98.49	0.00e+00	828.00
IUUC-Sha-107319	Sarcophilus harrisii	97.49	0.00e+00	820.00
IUUC-Ssc-115865	Sus scrofa	99.50	0.00e+00	834.00
IUUC-Tgu-117225	Taeniopygia guttata	95.98	0.00e+00	809.00
IUUC-Tru-118026	Takifugu rubripes	89.70	0.00e+00	754.00
IUUC-Tsy-119407	Tarsius syrichta	99.48	0.00e+00	812.00
IUUC-Tni-120234	Tetraodon nigroviridis	92.51	4.00e-125	442.00
IUUC-Tur-126774	Triticum urartu	29.17	6.00e-46	179.00
IUUC-Tbe-127708	Tupaia belangeri	78.60	8.00e-94	338.00
IUUC-Ttr-128667	Tursiops truncatus	99.25	0.00e+00	832.00
IUUC-Vpa-130200	Vicugna pacos	99.50	0.00e+00	833.00
IUUC-Xtr-132176	Xenopus tropicalis	93.72	0.00e+00	789.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence