iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013204

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

F-box/LRR-repeat protein 5

Genbank Nucleotide ID

DAAA02018735

Gene Name

FBXL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000021214.5	ENSBTAT00000028266.5	ENSBTAP00000028266.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	4.70e-06	26.9	178	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 99   daglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           +++ +++lp e++v+i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 178  QSTGITHLPPEVMVSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 225
           5566889*********************************9****987 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

LLCTKLSKTN FSNNNDFRAL LQSLYATFKE FKMHEQIENE YIIGLLQQRS QTIYNVHSDN 60
KLSEMLSLFE KGLKNVKNEY EQLNYAKQLK ERLEAFTKDF LPHMKEEEEV FQPMLMEYFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTCTGTA CAAAACTAAG TAGGAATGCA TTTGAATATT TCCTCTTGAT GCATATTTGC 60
ATGTACTTAT TATGTCTTCT TTTTAATTTT TTCCAGCTTT CTAAAACCAA CTTTTCCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	96.11	0.00e+00	1214.00
IUUC-Apl-003755	Anas platyrhynchos	80.27	0.00e+00	1009.00
IUUC-Aca-004798	Anolis carolinensis	76.27	0.00e+00	997.00
IUUC-Ame-011091	Astyanax mexicanus	58.32	0.00e+00	716.00
IUUC-Cja-019594	Callithrix jacchus	93.45	0.00e+00	1018.00
IUUC-Cfa-020965	Canis familiaris	95.63	0.00e+00	1190.00
IUUC-Cpo-021308	Cavia porcellus	91.92	0.00e+00	1172.00
IUUC-Csa-023865	Chlorocebus sabaeus	93.71	0.00e+00	1233.00
IUUC-Cho-024778	Choloepus hoffmanni	82.37	9.00e-164	570.00
IUUC-Dre-027628	Danio rerio	53.36	6.00e-162	564.00
IUUC-Dno-029899	Dasypus novemcinctus	92.07	0.00e+00	1217.00
IUUC-Dor-031105	Dipodomys ordii	79.20	0.00e+00	984.00
IUUC-Ete-032314	Echinops telfairi	86.43	0.00e+00	1078.00
IUUC-Eca-033797	Equus caballus	94.81	0.00e+00	1155.00
IUUC-Eeu-034811	Erinaceus europaeus	85.04	0.00e+00	887.00
IUUC-Fca-036516	Felis catus	95.03	0.00e+00	1181.00
IUUC-Fal-036824	Ficedula albicollis	78.02	0.00e+00	939.00
IUUC-Gga-040271	Gallus gallus	80.12	0.00e+00	1023.00
IUUC-Gac-041399	Gasterosteus aculeatus	61.05	0.00e+00	748.00
IUUC-Ggo-044415	Gorilla gorilla	93.86	0.00e+00	1235.00
IUUC-Hsa-047001	Homo sapiens	93.86	0.00e+00	1247.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	92.23	0.00e+00	1025.00
IUUC-Lch-049897	Latimeria chalumnae	64.09	0.00e+00	785.00
IUUC-Loc-052162	Lepisosteus oculatus	64.86	0.00e+00	813.00
IUUC-Laf-054031	Loxodonta africana	92.96	0.00e+00	1192.00
IUUC-Mcc-054680	Macaca mulatta	94.01	0.00e+00	1238.00
IUUC-Meu-056199	Macropus eugenii	82.40	2.00e-103	370.00
IUUC-Mga-059675	Meleagris gallopavo	80.51	0.00e+00	1028.00
IUUC-Mmr-061694	Microcebus murinus	93.71	0.00e+00	1226.00
IUUC-Mdo-062900	Monodelphis domestica	88.02	0.00e+00	1146.00
IUUC-Mmu-063178	Mus musculus	90.99	0.00e+00	1186.00
IUUC-Mpu-066584	Mustela putorius furo	94.76	0.00e+00	1195.00
IUUC-Mlu-067859	Myotis lucifugus	94.28	0.00e+00	1188.00
IUUC-Nle-069172	Nomascus leucogenys	94.31	0.00e+00	1211.00
IUUC-Opr-070992	Ochotona princeps	88.25	0.00e+00	979.00
IUUC-Ont-072577	Oreochromis niloticus	60.93	0.00e+00	745.00
IUUC-Oan-072870	Ornithorhynchus anatinus	83.63	0.00e+00	895.00
IUUC-Ocu-074849	Oryctolagus cuniculus	92.04	0.00e+00	1191.00
IUUC-Ola-087146	Oryzias latipes	59.01	0.00e+00	730.00
IUUC-Oga-088307	Otolemur garnettii	93.41	0.00e+00	1220.00
IUUC-Oar-090192	Ovis aries	98.95	0.00e+00	1258.00
IUUC-Ptr-091049	Pan troglodytes	94.16	0.00e+00	1239.00
IUUC-Pan-091995	Papio anubis	93.86	0.00e+00	1235.00
IUUC-Psi-093154	Pelodiscus sinensis	79.28	0.00e+00	988.00
IUUC-Pma-094334	Petromyzon marinus	46.20	4.00e-138	484.00
IUUC-Pfo-096154	Poecilia formosa	60.12	0.00e+00	720.00
IUUC-Pab-098264	Pongo abelii	94.28	0.00e+00	1236.00
IUUC-Pca-100884	Procavia capensis	70.81	0.00e+00	863.00
IUUC-Pva-102114	Pteropus vampyrus	94.32	0.00e+00	1224.00
IUUC-Rno-105392	Rattus norvegicus	92.04	0.00e+00	1192.00
IUUC-Sha-106508	Sarcophilus harrisii	88.42	0.00e+00	1149.00
IUUC-Sar-113107	Sorex araneus	89.15	0.00e+00	827.00
IUUC-Ssc-115489	Sus scrofa	95.21	0.00e+00	1191.00
IUUC-Tgu-116734	Taeniopygia guttata	78.33	0.00e+00	990.00
IUUC-Tru-117632	Takifugu rubripes	60.00	0.00e+00	732.00
IUUC-Tsy-119400	Tarsius syrichta	92.76	0.00e+00	1196.00
IUUC-Tni-120602	Tetraodon nigroviridis	59.74	0.00e+00	744.00
IUUC-Tbe-127833	Tupaia belangeri	91.28	3.00e-180	624.00
IUUC-Ttr-129289	Tursiops truncatus	94.02	0.00e+00	735.00
IUUC-Vpa-130253	Vicugna pacos	95.30	0.00e+00	640.00
IUUC-Vvi-131468	Vitis vinifera	32.39	2.00e-05	43.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence