iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106508

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01219012

Gene Name

FBXL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004867.1	ENSSHAT00000005625.1	ENSSHAP00000005571.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	5.90e-06	26.6	202	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 100  aglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           ++++++lp e++++i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 202  STNITHLPPEVMLTIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 248
           467899*********************************9****987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

IFFFPPSCCI VTCCIFRAQS IKGRVYNQLS KTNFSNNNDF RALLQSLYAT FKEFKMHEQI 60
ENEYIIGLLQ QRSRTIYNVH SDNKLSEMLS LFEKGLKNVK NEYEQLNYAK QLKERLEAFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTTTTTTT TTCCTCCAAG TTGTTGTTCT TGTTGTTTTT TGGCTGAGTT GGGGTTAAGT 60
GATTTACCCA GGGTCACACA GCTAGGAAGT ATTAAGTGTC TGAGATCAGA TTTGAACTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	89.70	0.00e+00	1137.00
IUUC-Apl-003755	Anas platyrhynchos	81.95	0.00e+00	1025.00
IUUC-Aca-004798	Anolis carolinensis	74.96	0.00e+00	985.00
IUUC-Ame-011091	Astyanax mexicanus	57.32	0.00e+00	729.00
IUUC-Bta-013204	Bos taurus	88.42	0.00e+00	1137.00
IUUC-Bol-015838	Brassica oleracea	28.09	3.00e-04	38.90
IUUC-Cja-019594	Callithrix jacchus	87.63	0.00e+00	965.00
IUUC-Cfa-020965	Canis familiaris	87.08	0.00e+00	1128.00
IUUC-Cpo-021308	Cavia porcellus	85.34	0.00e+00	1120.00
IUUC-Csa-023865	Chlorocebus sabaeus	86.50	0.00e+00	1177.00
IUUC-Cho-024778	Choloepus hoffmanni	82.42	4.00e-161	561.00
IUUC-Dre-027628	Danio rerio	52.20	4.00e-163	568.00
IUUC-Dno-029899	Dasypus novemcinctus	86.53	0.00e+00	1179.00
IUUC-Dor-031105	Dipodomys ordii	73.36	0.00e+00	948.00
IUUC-Ete-032314	Echinops telfairi	83.43	0.00e+00	1038.00
IUUC-Eca-033797	Equus caballus	89.17	0.00e+00	1090.00
IUUC-Eeu-034811	Erinaceus europaeus	80.14	0.00e+00	845.00
IUUC-Fca-036516	Felis catus	89.17	0.00e+00	1117.00
IUUC-Fal-036824	Ficedula albicollis	80.25	0.00e+00	962.00
IUUC-Gga-040271	Gallus gallus	80.14	0.00e+00	1042.00
IUUC-Gac-041399	Gasterosteus aculeatus	58.43	0.00e+00	741.00
IUUC-Ggo-044415	Gorilla gorilla	86.94	0.00e+00	1179.00
IUUC-Hsa-047001	Homo sapiens	86.94	0.00e+00	1198.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	87.18	0.00e+00	976.00
IUUC-Lch-049897	Latimeria chalumnae	64.37	0.00e+00	798.00
IUUC-Loc-052162	Lepisosteus oculatus	63.30	0.00e+00	811.00
IUUC-Laf-054031	Loxodonta africana	87.08	0.00e+00	1156.00
IUUC-Mcc-054680	Macaca mulatta	86.65	0.00e+00	1179.00
IUUC-Meu-056199	Macropus eugenii	93.97	1.00e-120	427.00
IUUC-Mga-059675	Meleagris gallopavo	81.97	0.00e+00	1044.00
IUUC-Mmr-061694	Microcebus murinus	86.21	0.00e+00	1170.00
IUUC-Mdo-062900	Monodelphis domestica	93.61	0.00e+00	1252.00
IUUC-Mmu-063178	Mus musculus	85.05	0.00e+00	1145.00
IUUC-Mpu-066584	Mustela putorius furo	86.65	0.00e+00	1122.00
IUUC-Mlu-067859	Myotis lucifugus	89.77	0.00e+00	1135.00
IUUC-Nle-069172	Nomascus leucogenys	86.94	0.00e+00	1154.00
IUUC-Opr-070992	Ochotona princeps	85.71	0.00e+00	961.00
IUUC-Ont-072577	Oreochromis niloticus	58.53	0.00e+00	740.00
IUUC-Oan-072870	Ornithorhynchus anatinus	85.44	0.00e+00	915.00
IUUC-Ocu-074849	Oryctolagus cuniculus	89.31	0.00e+00	1155.00
IUUC-Ola-087146	Oryzias latipes	58.87	0.00e+00	733.00
IUUC-Oga-088307	Otolemur garnettii	89.02	0.00e+00	1160.00
IUUC-Oar-090192	Ovis aries	86.42	0.00e+00	1147.00
IUUC-Ptr-091049	Pan troglodytes	87.08	0.00e+00	1182.00
IUUC-Pan-091995	Papio anubis	86.65	0.00e+00	1180.00
IUUC-Psi-093154	Pelodiscus sinensis	82.76	0.00e+00	1021.00
IUUC-Pma-094334	Petromyzon marinus	47.02	2.00e-141	495.00
IUUC-Pfo-096154	Poecilia formosa	57.18	0.00e+00	720.00
IUUC-Pab-098264	Pongo abelii	89.32	0.00e+00	1177.00
IUUC-Pca-100884	Procavia capensis	74.42	5.00e-175	607.00
IUUC-Pva-102114	Pteropus vampyrus	86.96	0.00e+00	1170.00
IUUC-Rno-105392	Rattus norvegicus	85.63	0.00e+00	1150.00
IUUC-Stu-112725	Solanum tuberosum	32.00	2.00e-04	40.00
IUUC-Sar-113107	Sorex araneus	86.22	0.00e+00	808.00
IUUC-Ssc-115489	Sus scrofa	86.94	0.00e+00	1123.00
IUUC-Tgu-116734	Taeniopygia guttata	79.35	0.00e+00	1009.00
IUUC-Tru-117632	Takifugu rubripes	57.85	0.00e+00	714.00
IUUC-Tsy-119400	Tarsius syrichta	88.25	0.00e+00	1132.00
IUUC-Tni-120602	Tetraodon nigroviridis	56.98	0.00e+00	730.00
IUUC-Tbe-127833	Tupaia belangeri	83.43	4.00e-167	581.00
IUUC-Ttr-129289	Tursiops truncatus	86.21	0.00e+00	687.00
IUUC-Uma-129641	Ustilago maydis	26.83	2.00e-05	45.10
IUUC-Vpa-130253	Vicugna pacos	93.11	1.00e-179	623.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence