iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013325

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Methylosome protein 50

Genbank Nucleotide ID

DAAA02007524

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000014102.3	ENSBTAT00000018753.3	ENSBTAP00000018753.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-17	63.2	166	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     d  ++s++ D+ i +WD+r+ +
   Q: 166  HSGQVTCVAAsphKDSVFLSCGEDNRILLWDTRCPK 201
           9*******9886644789*************99876 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCTGGAGCT GAATCTCAGG CGGGCATCCA ATTTGGGTCT AGATTGAAGT TGGAACCGTG 60
GAGATGCGGA AGGAAACACC GCCTCCCCTA GTGCCCCCGG CAGCCCGGGA GTGGAACCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	94.75	0.00e+00	638.00
IUUC-Apl-003921	Anas platyrhynchos	66.48	4.00e-67	247.00
IUUC-Aca-004870	Anolis carolinensis	70.61	1.00e-120	425.00
IUUC-Ame-011872	Astyanax mexicanus	48.35	6.00e-38	150.00
IUUC-Cja-019059	Callithrix jacchus	93.27	0.00e+00	633.00
IUUC-Cfa-021036	Canis familiaris	94.50	1.00e-161	562.00
IUUC-Cpo-022369	Cavia porcellus	91.52	2.00e-180	624.00
IUUC-Csa-023585	Chlorocebus sabaeus	93.27	0.00e+00	634.00
IUUC-Cho-024470	Choloepus hoffmanni	84.65	8.00e-117	412.00
IUUC-Dno-029867	Dasypus novemcinctus	91.23	2.00e-180	624.00
IUUC-Dor-030834	Dipodomys ordii	63.85	4.00e-114	404.00
IUUC-Ete-032245	Echinops telfairi	83.16	4.00e-140	490.00
IUUC-Eca-033360	Equus caballus	93.86	3.00e-177	613.00
IUUC-Eeu-035353	Erinaceus europaeus	91.23	6.00e-179	619.00
IUUC-Fca-036277	Felis catus	95.61	0.00e+00	646.00
IUUC-Fal-037383	Ficedula albicollis	69.44	5.00e-103	367.00
IUUC-Gmo-038575	Gadus morhua	53.45	1.00e-97	349.00
IUUC-Gga-040658	Gallus gallus	72.44	9.00e-131	459.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.66	2.00e-85	308.00
IUUC-Ggo-045120	Gorilla gorilla	91.81	0.00e+00	627.00
IUUC-Hsa-046247	Homo sapiens	92.11	0.00e+00	629.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	92.40	3.00e-177	614.00
IUUC-Lch-049741	Latimeria chalumnae	66.14	6.00e-113	400.00
IUUC-Loc-052695	Lepisosteus oculatus	58.68	2.00e-105	375.00
IUUC-Laf-054535	Loxodonta africana	90.23	2.00e-178	617.00
IUUC-Mcc-054699	Macaca mulatta	93.27	0.00e+00	634.00
IUUC-Meu-056053	Macropus eugenii	75.80	3.00e-137	481.00
IUUC-Mga-059672	Meleagris gallopavo	68.33	5.00e-73	266.00
IUUC-Mmr-060963	Microcebus murinus	94.74	0.00e+00	645.00
IUUC-Mdo-062694	Monodelphis domestica	72.62	1.00e-130	459.00
IUUC-Mmu-064031	Mus musculus	88.60	1.00e-175	608.00
IUUC-Mpu-066408	Mustela putorius furo	95.61	0.00e+00	646.00
IUUC-Mlu-068184	Myotis lucifugus	93.00	0.00e+00	626.00
IUUC-Nle-069251	Nomascus leucogenys	92.98	0.00e+00	634.00
IUUC-Opr-071156	Ochotona princeps	84.50	7.00e-165	572.00
IUUC-Ont-072683	Oreochromis niloticus	56.56	2.00e-95	342.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.69	2.00e-127	448.00
IUUC-Ocu-074843	Oryctolagus cuniculus	94.17	8.00e-179	619.00
IUUC-Ola-086929	Oryzias latipes	52.94	7.00e-88	317.00
IUUC-Oga-088237	Otolemur garnettii	92.98	0.00e+00	632.00
IUUC-Oar-089312	Ovis aries	99.68	4.00e-178	616.00
IUUC-Ptr-091625	Pan troglodytes	92.11	0.00e+00	628.00
IUUC-Pan-091902	Papio anubis	88.37	1.00e-171	595.00
IUUC-Psi-094035	Pelodiscus sinensis	72.98	2.00e-126	444.00
IUUC-Pma-094565	Petromyzon marinus	62.98	1.00e-56	212.00
IUUC-Pfo-097070	Poecilia formosa	54.17	3.00e-91	328.00
IUUC-Pab-098007	Pongo abelii	92.69	0.00e+00	632.00
IUUC-Pca-100513	Procavia capensis	75.19	2.00e-105	374.00
IUUC-Pva-102821	Pteropus vampyrus	88.60	6.00e-169	586.00
IUUC-Rno-105836	Rattus norvegicus	88.22	2.00e-177	614.00
IUUC-Sha-106847	Sarcophilus harrisii	70.00	2.00e-90	325.00
IUUC-Sar-113451	Sorex araneus	87.76	8.00e-173	599.00
IUUC-Ssc-115978	Sus scrofa	95.32	0.00e+00	626.00
IUUC-Tgu-116745	Taeniopygia guttata	69.30	1.00e-95	342.00
IUUC-Tru-117945	Takifugu rubripes	53.42	4.00e-80	291.00
IUUC-Tsy-119059	Tarsius syrichta	89.27	2.00e-91	327.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.46	2.00e-93	335.00
IUUC-Tbe-127559	Tupaia belangeri	95.03	0.00e+00	645.00
IUUC-Ttr-128505	Tursiops truncatus	94.15	0.00e+00	631.00
IUUC-Vpa-130350	Vicugna pacos	95.60	2.00e-102	364.00
IUUC-Xtr-132939	Xenopus tropicalis	61.35	6.00e-114	403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence