iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066408

Ensembl Protein ID

ENSMPUP00000004718.1

UniProt Accession

M3Y067; M3Y067_MUSPF

Genbank Protein ID

ENSMPUP00000004718

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01073830

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000004756.1	ENSMPUT00000004800.1	ENSMPUP00000004718.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-19	66.9	166	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     d +++s+s D+ i +WD+r+ +
   Q: 166  HSGQVTCVAAsphKDSMFLSCSEDNRILLWDTRCPK 201
           9*******988765599**************99876 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MRKETPPPLV PPAVREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCAGAAAA AACCACCCGG GACAGCATGG TCAAAAGGGT CCGCGCAGTA CGCTCTGCGT 60
CCCAGTGACC CCAACAAGAC ACTCTGTCAG GGGCAGGAGC AAGATGGTCG CTCACAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	97.96	0.00e+00	658.00
IUUC-Apl-003921	Anas platyrhynchos	62.11	2.00e-66	244.00
IUUC-Aca-004870	Anolis carolinensis	70.61	2.00e-121	428.00
IUUC-Ame-011872	Astyanax mexicanus	48.90	2.00e-38	151.00
IUUC-Bta-013325	Bos taurus	95.61	0.00e+00	646.00
IUUC-Cja-019059	Callithrix jacchus	93.27	0.00e+00	632.00
IUUC-Cfa-021036	Canis familiaris	96.56	2.00e-165	575.00
IUUC-Cpo-022369	Cavia porcellus	92.40	0.00e+00	630.00
IUUC-Csa-023585	Chlorocebus sabaeus	93.27	0.00e+00	634.00
IUUC-Cho-024470	Choloepus hoffmanni	85.89	3.00e-119	420.00
IUUC-Dno-029867	Dasypus novemcinctus	90.64	3.00e-180	623.00
IUUC-Dor-030834	Dipodomys ordii	64.43	3.00e-115	408.00
IUUC-Ete-032245	Echinops telfairi	83.85	6.00e-141	493.00
IUUC-Eca-033360	Equus caballus	93.57	4.00e-177	613.00
IUUC-Eeu-035353	Erinaceus europaeus	91.52	4.00e-180	623.00
IUUC-Fca-036277	Felis catus	97.66	0.00e+00	661.00
IUUC-Fal-037383	Ficedula albicollis	68.09	1.00e-103	369.00
IUUC-Gmo-038575	Gadus morhua	54.35	2.00e-99	355.00
IUUC-Gga-040658	Gallus gallus	70.55	4.00e-131	461.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.04	2.00e-84	305.00
IUUC-Ggo-045120	Gorilla gorilla	91.81	0.00e+00	626.00
IUUC-Hsa-046247	Homo sapiens	92.11	0.00e+00	628.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	92.98	2.00e-178	617.00
IUUC-Lch-049741	Latimeria chalumnae	65.82	4.00e-112	397.00
IUUC-Loc-052695	Lepisosteus oculatus	59.28	3.00e-106	378.00
IUUC-Laf-054535	Loxodonta africana	90.80	4.00e-179	620.00
IUUC-Mcc-054699	Macaca mulatta	93.27	0.00e+00	634.00
IUUC-Meu-056053	Macropus eugenii	77.48	6.00e-138	483.00
IUUC-Mga-059672	Meleagris gallopavo	65.46	8.00e-73	266.00
IUUC-Mmr-060963	Microcebus murinus	95.03	0.00e+00	647.00
IUUC-Mdo-062694	Monodelphis domestica	74.04	5.00e-131	460.00
IUUC-Mmu-064031	Mus musculus	88.30	8.00e-175	605.00
IUUC-Mlu-068184	Myotis lucifugus	92.13	3.00e-179	620.00
IUUC-Nle-069251	Nomascus leucogenys	92.98	0.00e+00	632.00
IUUC-Opr-071156	Ochotona princeps	83.92	9.00e-164	569.00
IUUC-Ont-072683	Oreochromis niloticus	57.63	5.00e-98	350.00
IUUC-Oan-073042	Ornithorhynchus anatinus	74.65	4.00e-125	440.00
IUUC-Ocu-074843	Oryctolagus cuniculus	93.59	2.00e-177	614.00
IUUC-Ola-086929	Oryzias latipes	53.25	1.00e-88	319.00
IUUC-Oga-088237	Otolemur garnettii	92.40	0.00e+00	629.00
IUUC-Oar-089312	Ovis aries	95.57	5.00e-171	593.00
IUUC-Ptr-091625	Pan troglodytes	92.11	0.00e+00	627.00
IUUC-Pan-091902	Papio anubis	88.92	2.00e-171	594.00
IUUC-Psi-094035	Pelodiscus sinensis	71.53	4.00e-127	447.00
IUUC-Pma-094565	Petromyzon marinus	63.54	2.00e-57	214.00
IUUC-Pfo-097070	Poecilia formosa	54.17	1.00e-91	329.00
IUUC-Pab-098007	Pongo abelii	92.69	0.00e+00	631.00
IUUC-Pca-100513	Procavia capensis	75.19	1.00e-105	375.00
IUUC-Pva-102821	Pteropus vampyrus	88.30	2.00e-168	584.00
IUUC-Rno-105836	Rattus norvegicus	88.22	3.00e-177	613.00
IUUC-Sha-106847	Sarcophilus harrisii	71.25	6.00e-89	320.00
IUUC-Sar-113451	Sorex araneus	87.46	4.00e-173	600.00
IUUC-Ssc-115978	Sus scrofa	94.15	9.00e-179	619.00
IUUC-Tgu-116745	Taeniopygia guttata	69.74	1.00e-96	345.00
IUUC-Tru-117945	Takifugu rubripes	54.35	3.00e-81	295.00
IUUC-Tsy-119059	Tarsius syrichta	88.14	2.00e-90	324.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.80	6.00e-94	337.00
IUUC-Tbe-127559	Tupaia belangeri	95.03	0.00e+00	646.00
IUUC-Ttr-128505	Tursiops truncatus	92.40	3.00e-179	620.00
IUUC-Vpa-130350	Vicugna pacos	97.25	2.00e-104	370.00
IUUC-Xtr-132939	Xenopus tropicalis	62.15	2.00e-113	401.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence