iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106847

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01176041

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013143.1	ENSSHAT00000015545.1	ENSSHAP00000015418.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-15	56.8	127	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtgv 34
           H+++v+++a  +    l++s++ D+ + +WDlr+ +
   Q: 127  HSGPVSSVAAsPHkeALFLSCGEDNRVLLWDLRCPK 162
           9*******9884434679**************9876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MGLARAPRRD ARVAQQEERR LGSGEPNWGS KDPAFNECSC FPASALSCLG VISGLLGTCF 60
QGAVELWELD EGERLIVNKF CKYEHDDIVT SVSVLVTGTQ AISGSKDFCI KFWDLSGERM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN CGAGATGGGA 60
ATGCAAAGCC CCTTCCCAGG CAGGTGCCCG GTCAGACTGG GGCTGGGATC AGGCAGCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

KEGG

shr:100916036

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	70.54	5.00e-97	347.00
IUUC-Apl-003921	Anas platyrhynchos	64.00	2.00e-61	228.00
IUUC-Aca-004870	Anolis carolinensis	60.50	2.00e-82	298.00
IUUC-Ame-011872	Astyanax mexicanus	50.00	3.00e-38	150.00
IUUC-Bta-013325	Bos taurus	70.00	5.00e-100	357.00
IUUC-Cja-019059	Callithrix jacchus	71.43	2.00e-100	358.00
IUUC-Cfa-021036	Canis familiaris	69.51	1.00e-98	353.00
IUUC-Cpo-022369	Cavia porcellus	71.67	1.00e-99	355.00
IUUC-Csa-023585	Chlorocebus sabaeus	70.61	2.00e-99	355.00
IUUC-Cho-024470	Choloepus hoffmanni	68.40	2.00e-88	318.00
IUUC-Dno-029867	Dasypus novemcinctus	70.37	1.00e-98	352.00
IUUC-Dor-030834	Dipodomys ordii	64.78	4.00e-77	281.00
IUUC-Dme-031923	Drosophila melanogaster	25.63	1.00e-11	63.90
IUUC-Ete-032245	Echinops telfairi	64.80	1.00e-88	319.00
IUUC-Eca-033360	Equus caballus	70.00	4.00e-97	347.00
IUUC-Eeu-035353	Erinaceus europaeus	69.17	1.00e-96	346.00
IUUC-Fca-036277	Felis catus	71.67	5.00e-99	353.00
IUUC-Fal-037383	Ficedula albicollis	62.75	4.00e-88	317.00
IUUC-Gmo-038575	Gadus morhua	51.04	6.00e-64	237.00
IUUC-Gga-040658	Gallus gallus	63.83	2.00e-85	308.00
IUUC-Gac-041463	Gasterosteus aculeatus	47.93	1.00e-56	213.00
IUUC-Ggo-045120	Gorilla gorilla	69.39	4.00e-98	350.00
IUUC-Hsa-046247	Homo sapiens	69.80	8.00e-99	353.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	71.60	9.00e-96	343.00
IUUC-Lch-049741	Latimeria chalumnae	58.82	4.00e-73	268.00
IUUC-Loc-052695	Lepisosteus oculatus	55.84	7.00e-68	250.00
IUUC-Laf-054535	Loxodonta africana	68.63	3.00e-98	351.00
IUUC-Mcc-054699	Macaca mulatta	70.61	2.00e-99	355.00
IUUC-Meu-056053	Macropus eugenii	78.80	8.00e-117	412.00
IUUC-Mga-059672	Meleagris gallopavo	59.79	1.00e-63	234.00
IUUC-Mmr-060963	Microcebus murinus	69.88	7.00e-100	357.00
IUUC-Mdo-062694	Monodelphis domestica	71.43	4.00e-104	370.00
IUUC-Mmu-064031	Mus musculus	69.51	4.00e-98	350.00
IUUC-Mpu-066408	Mustela putorius furo	71.25	8.00e-99	353.00
IUUC-Mlu-068184	Myotis lucifugus	68.92	6.00e-99	353.00
IUUC-Nle-069251	Nomascus leucogenys	70.20	4.00e-99	354.00
IUUC-Opr-071156	Ochotona princeps	62.25	4.00e-88	317.00
IUUC-Ont-072683	Oreochromis niloticus	51.27	9.00e-63	233.00
IUUC-Oan-073042	Ornithorhynchus anatinus	61.45	8.00e-82	296.00
IUUC-Ocu-074843	Oryctolagus cuniculus	69.92	4.00e-98	351.00
IUUC-Ola-086929	Oryzias latipes	48.68	5.00e-55	207.00
IUUC-Oga-088237	Otolemur garnettii	69.60	3.00e-100	358.00
IUUC-Oar-089312	Ovis aries	70.00	2.00e-100	358.00
IUUC-Ptr-091625	Pan troglodytes	69.80	9.00e-99	353.00
IUUC-Pan-091902	Papio anubis	70.61	1.00e-99	355.00
IUUC-Psi-094035	Pelodiscus sinensis	64.34	2.00e-90	325.00
IUUC-Pma-094565	Petromyzon marinus	49.43	1.00e-21	95.90
IUUC-Pfo-097070	Poecilia formosa	49.78	3.00e-61	228.00
IUUC-Pab-098007	Pongo abelii	69.80	1.00e-98	352.00
IUUC-Pca-100513	Procavia capensis	67.52	7.00e-41	160.00
IUUC-Pva-102821	Pteropus vampyrus	64.46	2.00e-86	312.00
IUUC-Rno-105836	Rattus norvegicus	68.65	9.00e-99	353.00
IUUC-Sar-113451	Sorex araneus	66.53	9.00e-92	329.00
IUUC-Ssc-115978	Sus scrofa	71.14	8.00e-97	346.00
IUUC-Tgu-116745	Taeniopygia guttata	66.08	6.00e-88	316.00
IUUC-Tru-117945	Takifugu rubripes	47.48	5.00e-59	221.00
IUUC-Tsy-119059	Tarsius syrichta	70.35	5.00e-67	246.00
IUUC-Tni-120414	Tetraodon nigroviridis	46.00	2.00e-59	222.00
IUUC-Tbe-127559	Tupaia belangeri	69.60	4.00e-100	357.00
IUUC-Ttr-128505	Tursiops truncatus	64.31	1.00e-98	352.00
IUUC-Vpa-130350	Vicugna pacos	71.63	7.00e-59	219.00
IUUC-Xtr-132939	Xenopus tropicalis	53.07	2.00e-76	278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence