iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tme-127097

Ensembl Protein ID

CAZ81645

UniProt Accession

D5GAV2; D5GAV2_TUBMM

Genbank Protein ID

CAZ81645.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

FN430086

Gene Name

GSTUM_00005321001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSTUM_00005321001	CAZ81645	CAZ81645

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.10e-68	228.6	17	541

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitele 101
           YDRQ+rlwG+++q++l++a++ l Ga+++GcE+lKnL+l  +g +tv+D++ ve+++l+ +F++++++ gk++Ae aa+ l elnpdv + +  ++++ + 
   Q: 17   YDRQLRLWGANGQNRLERAHIALFGATATGCEVLKNLILPSIGRFTVIDDKLVEQADLGVNFFLDQDSLGKPRAERAAALLGELNPDVAGGFRIDNLESIL 117
           ***************************************************************************************************** PP
   S: 102  eeiv.....FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpn.............. 181
            + +       ++f+  + +  ++ + + +    l a++p++ + +lG++  +r+  + +t+++ ++d   ++++ +P+++l e+                
   Q: 118  SNTPglldpRTTEFTHLL-LMSPIPTPLLLQ---LPAEIPIFFVHSLGFITSLRIYAPTHTIIEIHPDslVDLRLFNPWPELSEFALektstldvpesegg 214
           **9996655555555533.334444443322...345************************************************6555666666667888 PP
   S: 182  ...aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv 274
               ++ +i+++ l+ k+le++++++++  + +++ek+ +k  + +++++      een+ ea+++++  + + + +s +k++l+++ec+ +t+++ +fw+
   Q: 215  mgdHEHGHIPYVLLLLKYLEDWKQSHQGHLPGSYSEKTLFKSMIMDRMRTgvpgGIEENYVEAVNAVMGDLRTAELSSgTKEVLNDPECQSITSQTDEFWI 315
           888999999999*************************99999999999987777889******************************************** PP
   S: 275  ..............................................................................................sfcsnae 281
                                                                                                         +f + +e
   Q: 316  iaravkdfagsnnallplsgampdmkaesrgyvalqnlyrakaysdaaaverivrdymnrvqhpkrnqidrdaiqlfcrhsnflrrlnyrsiadEFSNSNE 416
           ***************************************************************************88877777777777777776666666 PP
   S: 282  alqvpekvekdeevvkasap.lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiep...kldddlikeiagniipaiattnavvgG 378
           +++    ++   + v++s    y++lra ++f + +gr pg+ s e  +++ +++ + ++    + +g ++   +  +++ kei++ + +++++t++  gG
   Q: 417  QHKGVVLGALGDWDVESSLIhHYIALRAYQEFYTGHGRAPGDTSHESCEEDYQEIRRIICE-YLKGIGYPEslpERCEKVAKEIVRAGGGELHVTASLAGG 516
           6665544444444444444478******************999888888866666665553.3355555551033456899******************** PP
   S: 379  laaqEviKvvsgkfeplknfflfda 403
           ++aqEviK+++ +++p++n+++fd+
   Q: 517  IVAQEVIKIITRQYVPINNTVIFDG 541
           ***********************97 PP

Organism

Tuber melanosporum

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MASSPPSGSP SSKEKKYDRQ LRLWGANGQN RLERAHIALF GATATGCEVL KNLILPSIGR 60
FTVIDDKLVE QADLGVNFFL DQDSLGKPRA ERAAALLGEL NPDVAGGFRI DNLESILSNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGTTCTTG TTGAACTATT ATATATATTC TCGCCCTTGG TCTCATTTCC ACTTTTTGTG 60
CTTCTCCGAA TTTCAATCTC TGAAAATATT TACAGTTACC CTGCGATCAT GGCTTCTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

tml:GSTUM_00005321001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	34.66	3.00e-83	300.00
IUUC-Aml-002333	Ailuropoda melanoleuca	38.95	1.00e-98	351.00
IUUC-Atr-002644	Amborella trichopoda	33.77	1.00e-72	265.00
IUUC-Apl-003446	Anas platyrhynchos	35.42	4.00e-88	316.00
IUUC-Aca-004450	Anolis carolinensis	36.31	1.00e-97	348.00
IUUC-Aly-006187	Arabidopsis lyrata	34.62	2.00e-85	307.00
IUUC-Ath-007600	Arabidopsis thaliana	35.53	9.00e-86	308.00
IUUC-Ago-007900	Ashbya gossypii	26.28	8.00e-22	96.30
IUUC-Acl-008333	Aspergillus clavatus	38.45	4.00e-93	333.00
IUUC-Afl-008529	Aspergillus flavus	40.00	4.00e-103	366.00
IUUC-Afu-009071	Aspergillus fumigatus	37.94	7.00e-92	329.00
IUUC-Ani-009443	Aspergillus nidulans	39.32	3.00e-95	340.00
IUUC-Ang-009669	Aspergillus niger	38.45	3.00e-101	360.00
IUUC-Aor-009914	Aspergillus oryzae	39.65	3.00e-100	357.00
IUUC-Ate-010450	Aspergillus terreus	37.66	1.00e-95	342.00
IUUC-Ame-011183	Astyanax mexicanus	37.75	1.00e-101	361.00
IUUC-Bgr-012111	Blumeria graminis	37.81	4.00e-87	313.00
IUUC-Bta-012583	Bos taurus	39.09	2.00e-100	357.00
IUUC-Bci-013892	Botrytis cinerea	38.97	8.00e-95	338.00
IUUC-Bdi-014592	Brachypodium distachyon	34.01	5.00e-81	293.00
IUUC-Bol-015487	Brassica oleracea	35.78	1.00e-87	315.00
IUUC-Bra-017506	Brassica rapa	35.78	4.00e-87	313.00
IUUC-Cel-018456	Caenorhabditis elegans	32.26	1.00e-67	249.00
IUUC-Cja-020007	Callithrix jacchus	38.70	8.00e-99	352.00
IUUC-Cfa-020324	Canis familiaris	39.27	3.00e-101	360.00
IUUC-Cpo-022248	Cavia porcellus	33.95	1.00e-50	192.00
IUUC-Csa-023149	Chlorocebus sabaeus	34.50	1.00e-72	265.00
IUUC-Cho-024537	Choloepus hoffmanni	31.82	2.00e-58	217.00
IUUC-Cin-025763	Ciona intestinalis	35.17	1.00e-92	331.00
IUUC-Csv-026113	Ciona savignyi	34.30	3.00e-87	313.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	37.80	1.00e-88	318.00
IUUC-Cne-026884	Cryptococcus neoformans	29.60	7.00e-67	246.00
IUUC-Cme-027210	Cyanidioschyzon merolae	19.54	2.00e-14	71.60
IUUC-Dre-028140	Danio rerio	36.66	8.00e-99	352.00
IUUC-Dno-030033	Dasypus novemcinctus	39.00	2.00e-86	310.00
IUUC-Dor-030513	Dipodomys ordii	58.59	1.00e-27	115.00
IUUC-Dse-031536	Dothistroma septosporum	39.93	1.00e-104	371.00
IUUC-Dme-031683	Drosophila melanogaster	34.99	3.00e-88	317.00
IUUC-Ete-032420	Echinops telfairi	33.83	2.00e-76	277.00
IUUC-Eca-033992	Equus caballus	35.12	4.00e-70	256.00
IUUC-Eeu-034713	Erinaceus europaeus	60.42	1.00e-29	122.00
IUUC-Fca-036548	Felis catus	38.73	6.00e-99	352.00
IUUC-Fal-037600	Ficedula albicollis	35.78	2.00e-88	317.00
IUUC-Fox-038037	Fusarium oxysporum	39.11	3.00e-96	343.00
IUUC-Fso-038387	Fusarium solani	40.11	3.00e-99	353.00
IUUC-Gmo-038562	Gadus morhua	36.09	1.00e-93	335.00
IUUC-Ggr-040005	Gaeumannomyces graminis	40.00	1.00e-98	351.00
IUUC-Gga-041129	Gallus gallus	36.40	2.00e-91	327.00
IUUC-Gac-042558	Gasterosteus aculeatus	37.39	5.00e-98	349.00
IUUC-Gma-043610	Glycine max	34.93	2.00e-84	304.00
IUUC-Ggo-045611	Gorilla gorilla	38.88	2.00e-98	350.00
IUUC-Hsa-046563	Homo sapiens	38.91	2.00e-99	353.00
IUUC-Hvu-047790	Hordeum vulgare	32.60	3.00e-54	203.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	39.09	4.00e-99	353.00
IUUC-Kpa-049309	Komagataella pastoris	33.70	1.00e-72	265.00
IUUC-Lch-050038	Latimeria chalumnae	39.01	6.00e-99	352.00
IUUC-Lpe-051535	Leersia perrieri	32.36	2.00e-62	231.00
IUUC-Loc-051917	Lepisosteus oculatus	34.99	3.00e-84	304.00
IUUC-Lma-053112	Leptosphaeria maculans	38.65	9.00e-106	375.00
IUUC-Laf-053690	Loxodonta africana	39.09	3.00e-101	360.00
IUUC-Mcc-055117	Macaca mulatta	38.63	1.00e-95	341.00
IUUC-Meu-056761	Macropus eugenii	31.70	1.00e-69	255.00
IUUC-Mor-057230	Magnaporthe oryzae	40.62	4.00e-102	363.00
IUUC-Mpo-057514	Magnaporthe poae	40.97	3.00e-93	333.00
IUUC-Mtr-058551	Medicago truncatula	34.36	6.00e-80	289.00
IUUC-Mla-059183	Melampsora laricipopulina	35.89	6.00e-89	319.00
IUUC-Mga-060144	Meleagris gallopavo	35.24	1.00e-86	311.00
IUUC-Mvi-060221	Microbotryum violaceum	34.68	2.00e-74	271.00
IUUC-Mmr-061325	Microcebus murinus	37.97	1.00e-94	338.00
IUUC-Mdo-062532	Monodelphis domestica	38.36	9.00e-99	352.00
IUUC-Mmu-063956	Mus musculus	39.63	2.00e-101	361.00
IUUC-Mac-064521	Musa acuminata	35.95	4.00e-85	306.00
IUUC-Mpu-066716	Mustela putorius furo	37.94	7.00e-88	316.00
IUUC-Mlu-067459	Myotis lucifugus	38.25	2.00e-99	354.00
IUUC-Nfi-068245	Neosartorya fischeri	38.65	2.00e-94	338.00
IUUC-Ncr-068910	Neurospora crassa	41.18	1.00e-103	368.00
IUUC-Nle-070034	Nomascus leucogenys	37.02	6.00e-90	322.00
IUUC-Opr-070552	Ochotona princeps	35.94	2.00e-74	270.00
IUUC-Ont-071426	Oreochromis niloticus	37.32	3.00e-99	353.00
IUUC-Oan-073389	Ornithorhynchus anatinus	34.12	1.00e-62	231.00
IUUC-Ocu-074911	Oryctolagus cuniculus	39.27	2.00e-100	357.00
IUUC-Oba-075437	Oryza barthii	34.06	5.00e-75	273.00
IUUC-Obr-076684	Oryza brachyantha	33.39	4.00e-67	247.00
IUUC-Ogl-077170	Oryza glaberrima	34.06	5.00e-75	273.00
IUUC-Ogu-078844	Oryza glumaepatula	33.71	1.00e-67	248.00
IUUC-Oin-079105	Oryza indica	34.06	2.00e-75	274.00
IUUC-Olo-080943	Oryza longistaminata	31.03	3.00e-59	220.00
IUUC-Oni-082891	Oryza nivara	31.51	2.00e-67	248.00
IUUC-Opu-083457	Oryza punctata	34.06	4.00e-74	270.00
IUUC-Oru-084960	Oryza rufipogon	31.03	3.00e-59	220.00
IUUC-Osa-085358	Oryza sativa	34.06	7.00e-75	272.00
IUUC-Ola-086420	Oryzias latipes	35.04	4.00e-63	233.00
IUUC-Olu-087625	Ostreococcus lucimarinus	28.06	2.00e-50	191.00
IUUC-Oga-088810	Otolemur garnettii	38.43	3.00e-100	356.00
IUUC-Oar-089196	Ovis aries	38.88	9.00e-99	352.00
IUUC-Ptr-090617	Pan troglodytes	38.91	2.00e-99	354.00
IUUC-Pan-092761	Papio anubis	39.27	1.00e-100	358.00
IUUC-Psi-093191	Pelodiscus sinensis	35.37	2.00e-90	324.00
IUUC-Pma-094380	Petromyzon marinus	35.60	1.00e-84	305.00
IUUC-Pno-095084	Phaeosphaeria nodorum	37.73	4.00e-93	334.00
IUUC-Ppa-095798	Physcomitrella patens	35.71	2.00e-82	297.00
IUUC-Pfo-096467	Poecilia formosa	36.23	1.00e-94	338.00
IUUC-Pab-098255	Pongo abelii	40.43	2.00e-86	310.00
IUUC-Pop-099722	Populus trichocarpa	34.19	4.00e-81	293.00
IUUC-Pca-100807	Procavia capensis	42.39	2.00e-34	137.00
IUUC-Ppe-101280	Prunus persica	35.79	1.00e-81	295.00
IUUC-Pva-102333	Pteropus vampyrus	36.78	4.00e-89	320.00
IUUC-Pgr-103401	Puccinia graminis	31.79	9.00e-74	269.00
IUUC-Ptt-103889	Puccinia triticina	28.91	1.00e-63	235.00
IUUC-Pte-104355	Pyrenophora teres	39.65	3.00e-104	370.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	39.89	9.00e-105	372.00
IUUC-Rno-105810	Rattus norvegicus	38.90	5.00e-99	353.00
IUUC-Sce-106397	Saccharomyces cerevisiae	26.03	5.00e-23	100.00
IUUC-Sha-106770	Sarcophilus harrisii	40.77	6.00e-53	198.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	32.97	2.00e-78	284.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.06	8.00e-73	265.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	41.20	6.00e-102	362.00
IUUC-Smo-109296	Selaginella moellendorffii	35.92	9.00e-84	302.00
IUUC-Sit-110157	Setaria italica	35.54	9.00e-87	312.00
IUUC-Sly-111105	Solanum lycopersicum	33.33	1.00e-81	295.00
IUUC-Stu-112469	Solanum tuberosum	33.75	6.00e-83	299.00
IUUC-Sar-113083	Sorex araneus	29.93	2.00e-60	224.00
IUUC-Sbi-113813	Sorghum bicolor	34.81	7.00e-85	305.00
IUUC-Sre-115058	Sporisorium reilianum	35.41	2.00e-68	251.00
IUUC-Tgu-116772	Taeniopygia guttata	36.00	2.00e-90	323.00
IUUC-Tru-118686	Takifugu rubripes	37.68	2.00e-101	360.00
IUUC-Tsy-119111	Tarsius syrichta	36.90	8.00e-42	162.00
IUUC-Tni-120231	Tetraodon nigroviridis	33.87	4.00e-82	296.00
IUUC-Tca-121491	Theobroma cacao	33.39	3.00e-75	273.00
IUUC-Tre-122103	Trichoderma reesei	42.12	5.00e-104	369.00
IUUC-Tvi-122672	Trichoderma virens	40.76	1.00e-96	345.00
IUUC-Tae-125316	Triticum aestivum	34.73	2.00e-83	300.00
IUUC-Tur-126487	Triticum urartu	33.58	8.00e-79	285.00
IUUC-Ttr-128465	Tursiops truncatus	36.41	2.00e-87	313.00
IUUC-Uma-129645	Ustilago maydis	32.29	4.00e-77	280.00
IUUC-Vda-129989	Verticillium dahliae	34.42	4.00e-72	263.00
IUUC-Vpa-130529	Vicugna pacos	37.61	2.00e-91	327.00
IUUC-Vvi-131059	Vitis vinifera	34.38	9.00e-78	282.00
IUUC-Xtr-132002	Xenopus tropicalis	39.38	2.00e-101	360.00
IUUC-Xma-133930	Xiphophorus maculatus	36.82	2.00e-95	341.00
IUUC-Yli-134505	Yarrowia lipolytica	32.36	6.00e-72	262.00
IUUC-Zma-135619	Zea mays	33.33	1.00e-79	288.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence