iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067481

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02004773

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003558.2	ENSMLUT00000003560.2	ENSMLUP00000003242.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-17	64.0	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.50e-10	40.2	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++ +++h+++L+a+S++F+  fl++ +e k k++v+++ v+   +  ++k+lY+ ++d+n+
   Q: 34   DCTLKAGDKSIPCHRLILSACSPYFREYFLSDIDEAK-KKEVVLDNVDSAMLDLIIKYLYSASIDLND 100
           9***********************************9.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 132  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 162
           56***************************99 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MESQRELAEE LRLYQSTLLQ DGLRDLLDEK KFIDCTLKAG DKSIPCHRLI LSACSPYFRE 60
YFLSDIDEAK KKEVVLDNVD SAMLDLIIKY LYSASIDLND GNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTAAGGCCT TCAGTGTCCC CTTCCTCACC CAGGTGACTC CCAACATGGA ATCGCAGCGG 60
GAACTCGCAG AGGAACTGCG GCTTTACCAA TCCACCCTTC TTCAGGATGG TCTAAGAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	94.22	0.00e+00	1156.00
IUUC-Apl-003866	Anas platyrhynchos	83.50	0.00e+00	1013.00
IUUC-Ame-011172	Astyanax mexicanus	61.19	0.00e+00	740.00
IUUC-Bta-012925	Bos taurus	95.21	0.00e+00	1163.00
IUUC-Bci-013875	Botrytis cinerea	30.05	1.00e-17	84.00
IUUC-Bdi-014457	Brachypodium distachyon	21.79	8.00e-10	58.50
IUUC-Cja-019348	Callithrix jacchus	94.39	0.00e+00	1161.00
IUUC-Cfa-020782	Canis familiaris	95.05	0.00e+00	1165.00
IUUC-Cpo-021825	Cavia porcellus	91.25	0.00e+00	1118.00
IUUC-Csa-023184	Chlorocebus sabaeus	94.43	0.00e+00	995.00
IUUC-Cin-025237	Ciona intestinalis	29.57	2.00e-68	253.00
IUUC-Dre-028278	Danio rerio	59.27	0.00e+00	758.00
IUUC-Dno-029516	Dasypus novemcinctus	93.07	0.00e+00	1142.00
IUUC-Dor-030850	Dipodomys ordii	90.36	0.00e+00	747.00
IUUC-Ete-032697	Echinops telfairi	92.08	0.00e+00	1106.00
IUUC-Eca-033714	Equus caballus	95.21	0.00e+00	1166.00
IUUC-Eeu-035245	Erinaceus europaeus	93.32	0.00e+00	1055.00
IUUC-Gmo-039392	Gadus morhua	57.21	0.00e+00	723.00
IUUC-Gga-041106	Gallus gallus	83.17	0.00e+00	1031.00
IUUC-Gac-042252	Gasterosteus aculeatus	61.46	0.00e+00	779.00
IUUC-Ggo-044817	Gorilla gorilla	94.72	0.00e+00	1162.00
IUUC-Hsa-046620	Homo sapiens	94.72	0.00e+00	1162.00
IUUC-Lch-050477	Latimeria chalumnae	67.99	0.00e+00	834.00
IUUC-Loc-051955	Lepisosteus oculatus	69.31	0.00e+00	897.00
IUUC-Laf-053500	Loxodonta africana	94.22	0.00e+00	1150.00
IUUC-Mcc-055316	Macaca mulatta	94.55	0.00e+00	1161.00
IUUC-Mmr-061444	Microcebus murinus	94.55	0.00e+00	1159.00
IUUC-Mmu-064147	Mus musculus	93.56	0.00e+00	1145.00
IUUC-Nle-069339	Nomascus leucogenys	94.88	0.00e+00	1164.00
IUUC-Opr-070703	Ochotona princeps	93.89	0.00e+00	1109.00
IUUC-Ont-072420	Oreochromis niloticus	60.30	0.00e+00	789.00
IUUC-Oan-073476	Ornithorhynchus anatinus	92.24	0.00e+00	1123.00
IUUC-Ocu-074248	Oryctolagus cuniculus	94.72	0.00e+00	1165.00
IUUC-Opu-083272	Oryza punctata	25.35	3.00e-07	49.70
IUUC-Ola-086361	Oryzias latipes	62.67	0.00e+00	776.00
IUUC-Oar-090349	Ovis aries	94.88	0.00e+00	1159.00
IUUC-Pan-092069	Papio anubis	94.72	0.00e+00	1163.00
IUUC-Psi-093671	Pelodiscus sinensis	85.64	0.00e+00	1030.00
IUUC-Pfo-096122	Poecilia formosa	62.96	0.00e+00	808.00
IUUC-Pab-098711	Pongo abelii	94.55	0.00e+00	1161.00
IUUC-Pop-099704	Populus trichocarpa	25.93	2.00e-10	60.50
IUUC-Pca-100495	Procavia capensis	86.30	0.00e+00	1035.00
IUUC-Pva-102401	Pteropus vampyrus	94.88	0.00e+00	1160.00
IUUC-Rno-105969	Rattus norvegicus	93.07	0.00e+00	1140.00
IUUC-Sar-113405	Sorex araneus	90.76	0.00e+00	1103.00
IUUC-Tgu-116725	Taeniopygia guttata	83.50	0.00e+00	1053.00
IUUC-Tru-117743	Takifugu rubripes	59.70	0.00e+00	763.00
IUUC-Tsy-119225	Tarsius syrichta	88.12	0.00e+00	1055.00
IUUC-Tni-120547	Tetraodon nigroviridis	62.40	0.00e+00	795.00
IUUC-Ttr-128645	Tursiops truncatus	94.55	0.00e+00	1159.00
IUUC-Vpa-130714	Vicugna pacos	94.88	0.00e+00	1162.00
IUUC-Xtr-132144	Xenopus tropicalis	75.25	0.00e+00	934.00
IUUC-Xma-133860	Xiphophorus maculatus	63.12	0.00e+00	809.00
IUUC-Yli-134535	Yarrowia lipolytica	23.64	1.00e-06	47.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence