iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afl-008535

Ensembl Protein ID

EED52698

UniProt Accession

B8NB25; B8NB25_ASPFN

Genbank Protein ID

EED52698.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

EQ963476

Gene Name

AFLA_044000

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AFLA_044000	EED52698	EED52698

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-27	93.8	63	96
UBD/Beta-Prp	7.30e-59	198.8	3	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H d ++++a  ++ ++++++sdD tik+WD+ +g
   Q: 63   HPDYIRSIAVhPTqPFVLTASDDMTIKLWDWEKG 96
           99********9888****************8765 PP

UBD/Beta-Prp

   S: 33   tikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetl 133
            + +w+++t++ +++++  + +v+a +f+ +++++v gs+D  ++v++++t++ + ++++h d+++s++++p++ +++++s+d ti++wd+e+g++  ++ 
   Q: 3    HVYIWSYETQSIIKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRVYNYNTSEKIASFEAHPDYIRSIAVHPTQPFVLTASDDMTIKLWDWEKGWKCVQVY 103
           578*******************************************************************************************98888** PP
   S: 134  sghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs 231
           +gh + v++++++p++ n ++s++lDrtv++W+l +     tl+   t+ v+ +++ ++   ++l++ s+d+tvk+wd+ t+  + tl+ght+nv+    +
   Q: 104  EGHAHYVMGLSINPKDtNTFASACLDRTVKIWSLGSPHANFTLEAHETKGVNYVDYYPQAdkPYLLTTSDDKTVKIWDYTTKALIATLEGHTSNVSFACYH 204
           *********************************************99********8887777*************************************** PP
   S: 232  pnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvn 290
           p+   ++sgs+Dg+i+iW   +  l ++l++  ++ ++va+ + g++ ++ g +d+ v 
   Q: 205  PELPVIISGSEDGTIKIWHANTYRLEQSLSYGLERAWCVAY-QRGKQGIAMGFDDGAVV 262
           ****************************************9.55555555554454443 PP

Organism

Aspergillus flavus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MGHVYIWSYE TQSIIKTFEL TDVPVRAGRF IARKNWIVCG SDDFQLRVYN YNTSEKIASF 60
EAHPDYIRSI AVHPTQPFVL TASDDMTIKL WDWEKGWKCV QVYEGHAHYV MGLSINPKDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTGAGT GCCTCTACGA TCTCAGGTGC CGACACATTA TACTGACTGG CCTCAGATCC 60
TGACAACCTT ATACAGCGGT GCGTTGGGGG ATCTGCATTT AAATGGTTAT AGGCCGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

afv:AFLA_044000

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	48.27	0.00e+00	750.00
IUUC-Aml-002154	Ailuropoda melanoleuca	54.46	0.00e+00	920.00
IUUC-Atr-003090	Amborella trichopoda	55.17	0.00e+00	846.00
IUUC-Apl-003976	Anas platyrhynchos	53.75	0.00e+00	916.00
IUUC-Aca-004301	Anolis carolinensis	52.80	0.00e+00	922.00
IUUC-Aly-005643	Arabidopsis lyrata	50.42	0.00e+00	837.00
IUUC-Ath-007635	Arabidopsis thaliana	51.32	0.00e+00	839.00
IUUC-Ago-007914	Ashbya gossypii	50.50	0.00e+00	810.00
IUUC-Acl-008237	Aspergillus clavatus	93.18	0.00e+00	1565.00
IUUC-Afu-008845	Aspergillus fumigatus	92.33	0.00e+00	1540.00
IUUC-Ani-009135	Aspergillus nidulans	90.23	0.00e+00	1459.00
IUUC-Ang-009654	Aspergillus niger	95.66	0.00e+00	1263.00
IUUC-Aor-009939	Aspergillus oryzae	99.88	0.00e+00	1692.00
IUUC-Ate-010355	Aspergillus terreus	94.10	0.00e+00	1506.00
IUUC-Ame-010922	Astyanax mexicanus	49.15	0.00e+00	793.00
IUUC-Bgr-012249	Blumeria graminis	77.68	0.00e+00	1286.00
IUUC-Bta-013579	Bos taurus	56.70	0.00e+00	879.00
IUUC-Bci-013866	Botrytis cinerea	78.36	0.00e+00	1277.00
IUUC-Bdi-015046	Brachypodium distachyon	51.55	0.00e+00	860.00
IUUC-Bol-016271	Brassica oleracea	51.08	0.00e+00	848.00
IUUC-Bra-017758	Brassica rapa	50.89	0.00e+00	848.00
IUUC-Cel-018387	Caenorhabditis elegans	50.25	0.00e+00	834.00
IUUC-Cja-019145	Callithrix jacchus	54.46	0.00e+00	920.00
IUUC-Cfa-020564	Canis familiaris	54.46	0.00e+00	920.00
IUUC-Cpo-022201	Cavia porcellus	54.59	0.00e+00	922.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	53.50	0.00e+00	812.00
IUUC-Csa-023383	Chlorocebus sabaeus	58.32	0.00e+00	694.00
IUUC-Cho-024454	Choloepus hoffmanni	52.27	0.00e+00	783.00
IUUC-Cin-025681	Ciona intestinalis	51.10	0.00e+00	832.00
IUUC-Csv-026012	Ciona savignyi	51.71	0.00e+00	835.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	73.09	0.00e+00	1150.00
IUUC-Cne-026986	Cryptococcus neoformans	57.23	0.00e+00	937.00
IUUC-Cme-027219	Cyanidioschyzon merolae	45.89	0.00e+00	750.00
IUUC-Dre-027846	Danio rerio	53.11	0.00e+00	920.00
IUUC-Dor-030462	Dipodomys ordii	53.48	0.00e+00	734.00
IUUC-Dse-031268	Dothistroma septosporum	77.33	0.00e+00	1276.00
IUUC-Dme-031791	Drosophila melanogaster	52.66	0.00e+00	857.00
IUUC-Ete-033166	Echinops telfairi	51.52	2.00e-164	570.00
IUUC-Eca-034180	Equus caballus	53.12	0.00e+00	879.00
IUUC-Eeu-035086	Erinaceus europaeus	42.25	2.00e-104	371.00
IUUC-Fca-036265	Felis catus	54.46	0.00e+00	919.00
IUUC-Fal-037202	Ficedula albicollis	53.62	0.00e+00	917.00
IUUC-Fox-037711	Fusarium oxysporum	78.13	0.00e+00	1194.00
IUUC-Fso-038268	Fusarium solani	78.10	0.00e+00	1190.00
IUUC-Gmo-039046	Gadus morhua	52.38	0.00e+00	907.00
IUUC-Ggr-039863	Gaeumannomyces graminis	78.83	0.00e+00	1243.00
IUUC-Gga-041112	Gallus gallus	53.06	0.00e+00	920.00
IUUC-Gac-041733	Gasterosteus aculeatus	53.60	0.00e+00	892.00
IUUC-Gma-044333	Glycine max	51.99	0.00e+00	867.00
IUUC-Ggo-044984	Gorilla gorilla	54.46	0.00e+00	919.00
IUUC-Hsa-046698	Homo sapiens	54.34	0.00e+00	919.00
IUUC-Hvu-047669	Hordeum vulgare	59.69	1.00e-126	443.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	54.46	0.00e+00	919.00
IUUC-Kpa-049265	Komagataella pastoris	54.47	0.00e+00	912.00
IUUC-Lch-050473	Latimeria chalumnae	54.13	0.00e+00	910.00
IUUC-Lpe-051579	Leersia perrieri	51.24	0.00e+00	860.00
IUUC-Loc-052675	Lepisosteus oculatus	52.63	0.00e+00	917.00
IUUC-Lma-053218	Leptosphaeria maculans	74.11	0.00e+00	1205.00
IUUC-Laf-053757	Loxodonta africana	54.20	0.00e+00	912.00
IUUC-Mcc-054859	Macaca mulatta	54.46	0.00e+00	921.00
IUUC-Meu-056174	Macropus eugenii	44.36	3.00e-91	327.00
IUUC-Mor-057264	Magnaporthe oryzae	79.46	0.00e+00	1230.00
IUUC-Mpo-057538	Magnaporthe poae	79.34	0.00e+00	1269.00
IUUC-Mtr-058310	Medicago truncatula	51.71	0.00e+00	866.00
IUUC-Mla-058937	Melampsora laricipopulina	56.49	0.00e+00	920.00
IUUC-Mga-059875	Meleagris gallopavo	52.81	0.00e+00	914.00
IUUC-Mvi-060240	Microbotryum violaceum	57.36	0.00e+00	950.00
IUUC-Mmr-061261	Microcebus murinus	54.46	0.00e+00	919.00
IUUC-Mdo-062076	Monodelphis domestica	53.31	0.00e+00	923.00
IUUC-Mmu-063324	Mus musculus	54.46	0.00e+00	920.00
IUUC-Mac-065544	Musa acuminata	51.74	0.00e+00	850.00
IUUC-Mpu-065961	Mustela putorius furo	54.46	0.00e+00	919.00
IUUC-Mlu-067059	Myotis lucifugus	53.70	0.00e+00	887.00
IUUC-Nfi-068277	Neosartorya fischeri	92.94	0.00e+00	1543.00
IUUC-Ncr-068659	Neurospora crassa	74.16	0.00e+00	1245.00
IUUC-Nle-069034	Nomascus leucogenys	54.46	0.00e+00	920.00
IUUC-Opr-070334	Ochotona princeps	56.82	0.00e+00	863.00
IUUC-Ont-071563	Oreochromis niloticus	53.16	0.00e+00	916.00
IUUC-Oan-073416	Ornithorhynchus anatinus	55.17	0.00e+00	923.00
IUUC-Ocu-074522	Oryctolagus cuniculus	54.34	0.00e+00	917.00
IUUC-Oba-075760	Oryza barthii	51.18	0.00e+00	865.00
IUUC-Obr-076163	Oryza brachyantha	51.12	0.00e+00	852.00
IUUC-Ogl-077450	Oryza glaberrima	50.93	0.00e+00	859.00
IUUC-Ogu-078994	Oryza glumaepatula	51.18	0.00e+00	863.00
IUUC-Oin-079211	Oryza indica	51.18	0.00e+00	863.00
IUUC-Olo-080731	Oryza longistaminata	51.06	0.00e+00	862.00
IUUC-Ome-081762	Oryza meridionalis	48.06	0.00e+00	802.00
IUUC-Oni-082324	Oryza nivara	51.18	0.00e+00	864.00
IUUC-Opu-083433	Oryza punctata	50.95	0.00e+00	846.00
IUUC-Oru-084829	Oryza rufipogon	51.18	0.00e+00	864.00
IUUC-Osa-086026	Oryza sativa	51.18	0.00e+00	863.00
IUUC-Ola-087245	Oryzias latipes	53.18	0.00e+00	916.00
IUUC-Olu-087655	Ostreococcus lucimarinus	52.05	0.00e+00	850.00
IUUC-Oga-088163	Otolemur garnettii	52.42	0.00e+00	874.00
IUUC-Oar-089842	Ovis aries	54.46	0.00e+00	920.00
IUUC-Ptr-090501	Pan troglodytes	54.46	0.00e+00	920.00
IUUC-Pan-092011	Papio anubis	54.46	0.00e+00	921.00
IUUC-Psi-093308	Pelodiscus sinensis	53.35	0.00e+00	918.00
IUUC-Pma-094695	Petromyzon marinus	54.24	0.00e+00	849.00
IUUC-Pno-094785	Phaeosphaeria nodorum	78.89	2.00e-139	487.00
IUUC-Ppa-095638	Physcomitrella patens	52.89	0.00e+00	870.00
IUUC-Pfo-096587	Poecilia formosa	53.24	0.00e+00	917.00
IUUC-Pab-097926	Pongo abelii	52.13	0.00e+00	847.00
IUUC-Pop-099634	Populus trichocarpa	52.15	0.00e+00	862.00
IUUC-Pca-100965	Procavia capensis	53.19	0.00e+00	881.00
IUUC-Ppe-101470	Prunus persica	51.86	0.00e+00	864.00
IUUC-Pva-102451	Pteropus vampyrus	52.69	0.00e+00	716.00
IUUC-Pgr-103453	Puccinia graminis	58.17	0.00e+00	953.00
IUUC-Ptt-103868	Puccinia triticina	58.05	0.00e+00	952.00
IUUC-Pte-104274	Pyrenophora teres	76.15	0.00e+00	1239.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	75.89	0.00e+00	1241.00
IUUC-Rno-105979	Rattus norvegicus	47.93	0.00e+00	682.00
IUUC-Sce-106269	Saccharomyces cerevisiae	49.68	0.00e+00	822.00
IUUC-Sha-106905	Sarcophilus harrisii	53.19	0.00e+00	922.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	52.25	0.00e+00	839.00
IUUC-Spo-108299	Schizosaccharomyces pombe	52.96	0.00e+00	867.00
IUUC-Smo-108828	Selaginella moellendorffii	50.63	0.00e+00	851.00
IUUC-Sit-110340	Setaria italica	50.73	0.00e+00	867.00
IUUC-Sly-111775	Solanum lycopersicum	52.70	0.00e+00	856.00
IUUC-Stu-112906	Solanum tuberosum	52.68	0.00e+00	824.00
IUUC-Sar-113472	Sorex araneus	52.66	0.00e+00	701.00
IUUC-Sbi-113801	Sorghum bicolor	51.67	0.00e+00	861.00
IUUC-Sre-115040	Sporisorium reilianum	56.66	0.00e+00	942.00
IUUC-Ssc-115593	Sus scrofa	54.34	0.00e+00	918.00
IUUC-Tgu-117239	Taeniopygia guttata	53.62	0.00e+00	917.00
IUUC-Tru-118025	Takifugu rubripes	52.80	0.00e+00	912.00
IUUC-Tsy-118824	Tarsius syrichta	51.51	0.00e+00	654.00
IUUC-Tni-120142	Tetraodon nigroviridis	53.11	0.00e+00	910.00
IUUC-Tca-121613	Theobroma cacao	52.10	0.00e+00	866.00
IUUC-Tre-122072	Trichoderma reesei	77.10	0.00e+00	1249.00
IUUC-Tvi-122546	Trichoderma virens	77.16	0.00e+00	1241.00
IUUC-Tae-125395	Triticum aestivum	51.96	0.00e+00	859.00
IUUC-Tur-126283	Triticum urartu	47.53	0.00e+00	744.00
IUUC-Tme-127041	Tuber melanosporum	75.06	0.00e+00	1268.00
IUUC-Tbe-127770	Tupaia belangeri	54.59	0.00e+00	753.00
IUUC-Ttr-129294	Tursiops truncatus	54.34	0.00e+00	916.00
IUUC-Uma-129351	Ustilago maydis	56.10	0.00e+00	945.00
IUUC-Vda-129716	Verticillium dahliae	78.44	0.00e+00	1307.00
IUUC-Vpa-130037	Vicugna pacos	45.63	1.00e-112	399.00
IUUC-Vvi-131689	Vitis vinifera	52.36	0.00e+00	865.00
IUUC-Xtr-132633	Xenopus tropicalis	54.52	0.00e+00	916.00
IUUC-Xma-133347	Xiphophorus maculatus	53.11	0.00e+00	915.00
IUUC-Yli-134455	Yarrowia lipolytica	57.69	0.00e+00	920.00
IUUC-Zma-135867	Zea mays	52.74	0.00e+00	873.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence