iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015466

Ensembl Protein ID

Bo6g080080.1

UniProt Accession

A0A0D3CVJ2; A0A0D3CVJ2_BRAOL

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo6g080080	Bo6g080080.1	Bo6g080080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-34	116.2	184	224
UBD/Beta-Prp	6.80e-66	224.0	13	292

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H  +v+c+++    d ++l++GsdD+t kvWD+ t +++++
   Q: 184  HLKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKTCVQT 224
           8889****966*9778********************99986 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           ++++++++v+ +p +++++++ ++gt+ +w+++t+++++s++  e +v++ kf +++++ v g++D++i+v++++t + + ++++h d++++++++p
   Q: 13   QRSERVKSVDLHPTEPWILASLYSGTVSIWNYQTQTMVKSFEVTELPVRSAKFVSRKQWVVAGADDMFIRVYNYNTMDKIKVFEAHADYIRCVAVHP 109
           667889******************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsg 198
           +  +++s s+d  i++wd+e++++  ++++gh++ v++v+++p++ n ++s+slDr +++W+l + +   tl   h + v++++     ++++l++g
   Q: 110  TLPYVLSSSDDMLIKLWDWEKDWVCTQIFEGHSHYVMHVTFNPKDtNTFASASLDRSIKIWNLGSPDPNFTLDA-HLKGVNCVDyfTGGDKPYLITG 205
           ***********************9999*********************************************98.*********6444555****** PP
   S: 199  sldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           s+d t k+wd+qt++cv+tl ght nv+ v f+p+  ++++gs+Dg++riW  ++  l +tl++  ++v+++ +++ +++v++  +e
   Q: 206  SDDHTAKVWDYQTKTCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGHMKGSHRVVIGYDE 292
           **************************************************************************8887887754444 PP

Organism

Brassica oleracea

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK FLQRSERVKS VDLHPTEPWI LASLYSGTVS IWNYQTQTMV KSFEVTELPV 60
RSAKFVSRKQ WVVAGADDMF IRVYNYNTMD KIKVFEAHAD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTTAGTG ATATGATCTC TCTCGCTTCC CCCCCTAGAT CTACTTCCCA ATCCATTTCA 60
GTTTTTAAAC ATCATGATCG TCTCTCGACG AAAGAGTGTG CTGCATTGCA CTAAAATTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	71.44	0.00e+00	1350.00
IUUC-Aly-005643	Arabidopsis lyrata	91.75	0.00e+00	1650.00
IUUC-Ath-007630	Arabidopsis thaliana	91.74	0.00e+00	1678.00
IUUC-Ago-007914	Ashbya gossypii	46.36	0.00e+00	717.00
IUUC-Acl-008237	Aspergillus clavatus	52.21	0.00e+00	900.00
IUUC-Afu-008845	Aspergillus fumigatus	52.61	0.00e+00	890.00
IUUC-Ani-009135	Aspergillus nidulans	52.79	0.00e+00	880.00
IUUC-Aor-009939	Aspergillus oryzae	52.00	0.00e+00	907.00
IUUC-Ate-010355	Aspergillus terreus	52.68	0.00e+00	875.00
IUUC-Bta-013579	Bos taurus	61.62	0.00e+00	966.00
IUUC-Bra-016617	Brassica rapa	98.79	0.00e+00	1672.00
IUUC-Cho-024454	Choloepus hoffmanni	58.42	0.00e+00	917.00
IUUC-Cin-025681	Ciona intestinalis	58.23	0.00e+00	997.00
IUUC-Csv-026012	Ciona savignyi	59.00	0.00e+00	970.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	50.00	0.00e+00	802.00
IUUC-Dse-031268	Dothistroma septosporum	52.32	0.00e+00	882.00
IUUC-Lma-053218	Leptosphaeria maculans	51.53	0.00e+00	862.00
IUUC-Mor-057264	Magnaporthe oryzae	53.44	0.00e+00	862.00
IUUC-Mla-058937	Melampsora laricipopulina	53.34	0.00e+00	891.00
IUUC-Nfi-068277	Neosartorya fischeri	52.29	0.00e+00	881.00
IUUC-Opr-070334	Ochotona princeps	62.36	0.00e+00	1000.00
IUUC-Oin-079211	Oryza indica	79.43	0.00e+00	1463.00
IUUC-Pno-094785	Phaeosphaeria nodorum	58.28	3.00e-104	372.00
IUUC-Pva-102451	Pteropus vampyrus	58.26	0.00e+00	846.00
IUUC-Pte-104274	Pyrenophora teres	52.80	0.00e+00	896.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	52.10	0.00e+00	844.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.47	0.00e+00	783.00
IUUC-Sar-113472	Sorex araneus	57.03	0.00e+00	764.00
IUUC-Tvi-122546	Trichoderma virens	53.08	0.00e+00	870.00
IUUC-Tur-126283	Triticum urartu	72.51	0.00e+00	1363.00
IUUC-Uma-129351	Ustilago maydis	50.37	0.00e+00	880.00
IUUC-Vda-129716	Verticillium dahliae	53.60	0.00e+00	900.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence