iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068659

Ensembl Protein ID

EAA33241

UniProt Accession

Q7SA43; Q7SA43_NEUCR

Genbank Protein ID

EAA33241.2

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

CM002239

Gene Name

NCU07319

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU07319	EAA33241	EAA33241

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-30	102.0	226	256
UBD/Beta-Prp	1.10e-65	220.8	13	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v+  ++ ++ ++++sGs Dgti++W+
   Q: 226  GHTNNVSFACYhPElPIIISGSEDGTIRIWN 256
           799999999999999***************9 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklv 110
           +++++ ++f+p +++++t+ ++g + +w+++t++ +++++  + +v+a +f+ ++++++ gs+D  i+v++++t++ + ++++h d+++++ ++p++ +++
   Q: 13   SERVKGIDFHPTEPWILTTLYSGHVYIWSYETQQIVKTFELTDVPVRAGRFIARKNWIICGSDDFQIRVYNYNTSEKITSFEAHPDYIRAICVHPTQPFVL 113
           678999*********************************************************************************************** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwd 208
           ++s+d ti++wd+e+g++   +++g+++ v++++++p++ n ++s++lDrtv++W+l + +   +l+   t+ v+++++ + +  ++l++ s+d+tvk+wd
   Q: 114  TASDDMTIKLWDWEKGWKNVRVFEGNSHYVMSLAINPKDtNTFASACLDRTVKIWSLGSSTPNFQLEAHETKGVNHVDYYPHSdkPYLLTTSDDRTVKVWD 214
           *******************99***********************************************99********8887777**************** PP
   S: 209  lqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvni 291
           + t++ + tl+ght+nv+    +p+  +++sgs+Dg+iriW+  +  + ++l++  ++ ++v++ + g++ ++ g +d++v i
   Q: 215  YTTKSLIATLEGHTNNVSFACYHPELPIIISGSEDGTIRIWNANTYRFEQSLNYGLERAWCVSY-QKGKQGIAVGFDDGSVVI 296
           ****************************************************************.666666666666777766 PP

Organism

Neurospora crassa

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDVKRQLF ARSERVKGID FHPTEPWILT TLYSGHVYIW SYETQQIVKT FELTDVPVRA 60
GRFIARKNWI ICGSDDFQIR VYNYNTSEKI TSFEAHPDYI RAICVHPTQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCGCTGTC ATTTCCGGCC CGTCGCAATC AAGTGTCAAG GCCTCCGAAG CCTCTATTCC 60
GAATCCTCGT ACCGCCAACC ACGTCCCCCC CCCTTCGGCG GACCAGATAT CCAATACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ncr:NCU07319

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	45.08	0.00e+00	755.00
IUUC-Aml-002154	Ailuropoda melanoleuca	52.70	0.00e+00	934.00
IUUC-Atr-003090	Amborella trichopoda	53.27	0.00e+00	880.00
IUUC-Apl-003976	Anas platyrhynchos	52.83	0.00e+00	936.00
IUUC-Aca-004301	Anolis carolinensis	52.70	0.00e+00	937.00
IUUC-Aly-006508	Arabidopsis lyrata	52.52	0.00e+00	889.00
IUUC-Ath-007635	Arabidopsis thaliana	52.64	0.00e+00	891.00
IUUC-Ago-007914	Ashbya gossypii	50.61	0.00e+00	839.00
IUUC-Acl-008237	Aspergillus clavatus	75.82	0.00e+00	1327.00
IUUC-Afl-008535	Aspergillus flavus	74.03	0.00e+00	1272.00
IUUC-Afu-008845	Aspergillus fumigatus	75.18	0.00e+00	1301.00
IUUC-Ani-009135	Aspergillus nidulans	75.27	0.00e+00	1287.00
IUUC-Ang-009654	Aspergillus niger	79.64	0.00e+00	1134.00
IUUC-Aor-009939	Aspergillus oryzae	75.33	0.00e+00	1349.00
IUUC-Ate-010355	Aspergillus terreus	75.39	0.00e+00	1286.00
IUUC-Ame-010922	Astyanax mexicanus	48.54	0.00e+00	811.00
IUUC-Bgr-012249	Blumeria graminis	78.31	0.00e+00	1335.00
IUUC-Bta-013579	Bos taurus	53.41	0.00e+00	847.00
IUUC-Bci-013866	Botrytis cinerea	80.27	0.00e+00	1328.00
IUUC-Bdi-015046	Brachypodium distachyon	52.88	0.00e+00	895.00
IUUC-Bol-016271	Brassica oleracea	52.64	0.00e+00	903.00
IUUC-Bra-017758	Brassica rapa	52.32	0.00e+00	901.00
IUUC-Cel-018387	Caenorhabditis elegans	50.12	0.00e+00	882.00
IUUC-Cja-019145	Callithrix jacchus	52.83	0.00e+00	934.00
IUUC-Cfa-020564	Canis familiaris	52.70	0.00e+00	933.00
IUUC-Cpo-022201	Cavia porcellus	52.83	0.00e+00	936.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	52.17	0.00e+00	831.00
IUUC-Csa-023383	Chlorocebus sabaeus	56.74	0.00e+00	721.00
IUUC-Cho-024454	Choloepus hoffmanni	50.00	0.00e+00	796.00
IUUC-Cin-025681	Ciona intestinalis	52.52	0.00e+00	874.00
IUUC-Csv-026012	Ciona savignyi	53.84	0.00e+00	870.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	78.30	0.00e+00	1266.00
IUUC-Cne-026986	Cryptococcus neoformans	55.65	0.00e+00	950.00
IUUC-Cme-027219	Cyanidioschyzon merolae	45.22	0.00e+00	768.00
IUUC-Dre-027846	Danio rerio	53.41	0.00e+00	941.00
IUUC-Dor-030462	Dipodomys ordii	51.87	0.00e+00	752.00
IUUC-Dse-031268	Dothistroma septosporum	74.43	0.00e+00	1289.00
IUUC-Dme-031791	Drosophila melanogaster	53.00	0.00e+00	903.00
IUUC-Ete-033166	Echinops telfairi	50.71	1.00e-174	605.00
IUUC-Eca-034180	Equus caballus	51.29	0.00e+00	892.00
IUUC-Eeu-035086	Erinaceus europaeus	40.00	2.00e-92	332.00
IUUC-Fca-036265	Felis catus	52.70	0.00e+00	933.00
IUUC-Fal-037202	Ficedula albicollis	52.10	0.00e+00	890.00
IUUC-Fox-037711	Fusarium oxysporum	83.78	0.00e+00	1308.00
IUUC-Fso-038268	Fusarium solani	83.46	0.00e+00	1315.00
IUUC-Gmo-039046	Gadus morhua	52.99	0.00e+00	929.00
IUUC-Ggr-039863	Gaeumannomyces graminis	84.28	0.00e+00	1353.00
IUUC-Gga-041112	Gallus gallus	52.95	0.00e+00	940.00
IUUC-Gac-041733	Gasterosteus aculeatus	53.19	0.00e+00	907.00
IUUC-Gma-044333	Glycine max	52.86	0.00e+00	908.00
IUUC-Ggo-044984	Gorilla gorilla	52.83	0.00e+00	934.00
IUUC-Hsa-046698	Homo sapiens	52.83	0.00e+00	933.00
IUUC-Hvu-047669	Hordeum vulgare	61.86	9.00e-141	491.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	52.70	0.00e+00	933.00
IUUC-Kpa-049265	Komagataella pastoris	57.37	0.00e+00	979.00
IUUC-Lch-050473	Latimeria chalumnae	52.58	0.00e+00	928.00
IUUC-Lpe-051579	Leersia perrieri	53.01	0.00e+00	892.00
IUUC-Loc-052675	Lepisosteus oculatus	53.07	0.00e+00	938.00
IUUC-Lma-053218	Leptosphaeria maculans	72.85	0.00e+00	1225.00
IUUC-Laf-053757	Loxodonta africana	52.45	0.00e+00	926.00
IUUC-Mcc-054859	Macaca mulatta	52.83	0.00e+00	934.00
IUUC-Meu-056174	Macropus eugenii	43.44	1.00e-82	299.00
IUUC-Mor-057264	Magnaporthe oryzae	83.45	0.00e+00	1334.00
IUUC-Mpo-057538	Magnaporthe poae	84.03	0.00e+00	1375.00
IUUC-Mtr-058310	Medicago truncatula	53.18	0.00e+00	914.00
IUUC-Mla-058937	Melampsora laricipopulina	56.37	0.00e+00	954.00
IUUC-Mga-059875	Meleagris gallopavo	52.82	0.00e+00	935.00
IUUC-Mvi-060240	Microbotryum violaceum	54.45	0.00e+00	951.00
IUUC-Mmr-061261	Microcebus murinus	52.70	0.00e+00	933.00
IUUC-Mdo-062076	Monodelphis domestica	52.95	0.00e+00	939.00
IUUC-Mmu-063324	Mus musculus	52.58	0.00e+00	933.00
IUUC-Mac-064636	Musa acuminata	49.54	0.00e+00	875.00
IUUC-Mpu-065961	Mustela putorius furo	52.70	0.00e+00	934.00
IUUC-Mlu-067059	Myotis lucifugus	52.21	0.00e+00	911.00
IUUC-Nfi-068277	Neosartorya fischeri	74.97	0.00e+00	1292.00
IUUC-Nle-069034	Nomascus leucogenys	52.83	0.00e+00	934.00
IUUC-Opr-070334	Ochotona princeps	54.66	0.00e+00	878.00
IUUC-Ont-071563	Oreochromis niloticus	52.93	0.00e+00	930.00
IUUC-Oan-073416	Ornithorhynchus anatinus	52.77	0.00e+00	890.00
IUUC-Ocu-074522	Oryctolagus cuniculus	52.70	0.00e+00	931.00
IUUC-Oba-075760	Oryza barthii	51.84	0.00e+00	878.00
IUUC-Obr-076201	Oryza brachyantha	52.76	0.00e+00	887.00
IUUC-Ogl-077450	Oryza glaberrima	52.45	0.00e+00	902.00
IUUC-Ogu-078994	Oryza glumaepatula	51.84	0.00e+00	878.00
IUUC-Oin-079856	Oryza indica	52.29	0.00e+00	881.00
IUUC-Olo-080731	Oryza longistaminata	52.34	0.00e+00	864.00
IUUC-Ome-081554	Oryza meridionalis	48.96	0.00e+00	813.00
IUUC-Oni-082324	Oryza nivara	51.84	0.00e+00	879.00
IUUC-Opu-083400	Oryza punctata	50.12	0.00e+00	858.00
IUUC-Oru-084829	Oryza rufipogon	51.84	0.00e+00	879.00
IUUC-Osa-086026	Oryza sativa	52.70	0.00e+00	906.00
IUUC-Ola-087245	Oryzias latipes	53.07	0.00e+00	936.00
IUUC-Olu-087655	Ostreococcus lucimarinus	51.97	0.00e+00	870.00
IUUC-Oga-088163	Otolemur garnettii	51.10	0.00e+00	891.00
IUUC-Oar-089842	Ovis aries	52.58	0.00e+00	935.00
IUUC-Ptr-090501	Pan troglodytes	52.83	0.00e+00	934.00
IUUC-Pan-092011	Papio anubis	52.83	0.00e+00	934.00
IUUC-Psi-093308	Pelodiscus sinensis	53.01	0.00e+00	936.00
IUUC-Pma-094695	Petromyzon marinus	52.44	0.00e+00	867.00
IUUC-Pno-094785	Phaeosphaeria nodorum	75.60	1.00e-134	471.00
IUUC-Ppa-095638	Physcomitrella patens	54.76	0.00e+00	922.00
IUUC-Pfo-096587	Poecilia formosa	53.07	0.00e+00	936.00
IUUC-Pab-097926	Pongo abelii	51.46	0.00e+00	863.00
IUUC-Pop-099634	Populus trichocarpa	53.04	0.00e+00	905.00
IUUC-Pca-100965	Procavia capensis	51.60	0.00e+00	897.00
IUUC-Ppe-101470	Prunus persica	53.06	0.00e+00	907.00
IUUC-Pva-102451	Pteropus vampyrus	51.27	0.00e+00	745.00
IUUC-Pgr-103453	Puccinia graminis	56.17	0.00e+00	975.00
IUUC-Ptt-103868	Puccinia triticina	55.92	0.00e+00	970.00
IUUC-Pte-104274	Pyrenophora teres	74.85	0.00e+00	1256.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	70.44	0.00e+00	1189.00
IUUC-Rno-105979	Rattus norvegicus	45.85	0.00e+00	701.00
IUUC-Sce-106269	Saccharomyces cerevisiae	52.55	0.00e+00	883.00
IUUC-Sha-106905	Sarcophilus harrisii	52.83	0.00e+00	937.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	53.16	0.00e+00	890.00
IUUC-Spo-108299	Schizosaccharomyces pombe	53.08	0.00e+00	904.00
IUUC-Smo-108695	Selaginella moellendorffii	51.47	0.00e+00	893.00
IUUC-Sit-110239	Setaria italica	50.81	0.00e+00	889.00
IUUC-Sly-111775	Solanum lycopersicum	53.22	0.00e+00	903.00
IUUC-Stu-112906	Solanum tuberosum	51.91	0.00e+00	811.00
IUUC-Sar-113472	Sorex araneus	50.40	0.00e+00	675.00
IUUC-Sbi-114052	Sorghum bicolor	52.27	0.00e+00	906.00
IUUC-Sre-115040	Sporisorium reilianum	56.74	0.00e+00	974.00
IUUC-Ssc-115593	Sus scrofa	52.58	0.00e+00	932.00
IUUC-Tgu-117239	Taeniopygia guttata	52.70	0.00e+00	935.00
IUUC-Tru-118025	Takifugu rubripes	52.83	0.00e+00	929.00
IUUC-Tsy-118824	Tarsius syrichta	50.63	0.00e+00	686.00
IUUC-Tni-120142	Tetraodon nigroviridis	52.77	0.00e+00	925.00
IUUC-Tca-121613	Theobroma cacao	53.00	0.00e+00	909.00
IUUC-Tre-122072	Trichoderma reesei	81.59	0.00e+00	1371.00
IUUC-Tvi-122546	Trichoderma virens	81.56	0.00e+00	1363.00
IUUC-Tae-125292	Triticum aestivum	52.45	0.00e+00	898.00
IUUC-Tur-126283	Triticum urartu	45.41	0.00e+00	754.00
IUUC-Tme-127041	Tuber melanosporum	73.06	0.00e+00	1273.00
IUUC-Tbe-127770	Tupaia belangeri	52.62	0.00e+00	768.00
IUUC-Ttr-129294	Tursiops truncatus	52.58	0.00e+00	929.00
IUUC-Uma-129351	Ustilago maydis	54.87	0.00e+00	969.00
IUUC-Vda-129716	Verticillium dahliae	82.48	0.00e+00	1399.00
IUUC-Vpa-130037	Vicugna pacos	42.16	4.00e-105	374.00
IUUC-Vvi-131689	Vitis vinifera	53.73	0.00e+00	909.00
IUUC-Xtr-132633	Xenopus tropicalis	53.11	0.00e+00	933.00
IUUC-Xma-133347	Xiphophorus maculatus	52.95	0.00e+00	934.00
IUUC-Yli-134455	Yarrowia lipolytica	56.92	0.00e+00	963.00
IUUC-Zma-135867	Zea mays	53.01	0.00e+00	909.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence