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Tag Content
iUUCD ID IUUC-Psi-093308
Ensembl Protein ID ENSPSIP00000009185.1
UniProt Accession K7FMC5; K7FMC5_PELSI
Genbank Protein ID ENSPSIP00000009185
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID AGCU01099872
Gene Name COPB2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPSIG00000008366.1 ENSPSIT00000009231.1 ENSPSIP00000009185.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.80e-34 114.5 183 224
UBD/Beta-Prp 1.50e-72 244.3 13 292
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++va
   Q: 190  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlgse 285
            l+ ++nv +  +e
   Q: 279  SLRGSNNVALGYDE 292
           *9999998755544 PP
   
Organism Pelodiscus sinensis
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Psi-093308|E3,WD_repeat;UBD,Beta-Prp|Pelodiscus sinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCACCTGC CCACGGCCGC TGGTCTCACT TCGCTGTGCA ATGACTACGT GTCCCAGGAT 60
GCATTACGGC ACATATGGAC TGCAATTCAA TCAGGCAGGC CCCGCTCCTA AGGCTTGATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Psi-093308|E3,WD_repeat;UBD,Beta-Prp|Pelodiscus sinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport
KEGG pss:102445325
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 53.04 0.00e+00 943.00
IUUC-Aml-002154 Ailuropoda melanoleuca 91.51 0.00e+00 1735.00
IUUC-Atr-003090 Amborella trichopoda 58.66 0.00e+00 1077.00
IUUC-Apl-003976 Anas platyrhynchos 95.92 0.00e+00 1749.00
IUUC-Aca-004301 Anolis carolinensis 97.27 0.00e+00 1722.00
IUUC-Aly-006508 Arabidopsis lyrata 60.36 0.00e+00 1097.00
IUUC-Ath-007630 Arabidopsis thaliana 62.06 0.00e+00 1109.00
IUUC-Ago-007914 Ashbya gossypii 46.19 0.00e+00 758.00
IUUC-Acl-008237 Aspergillus clavatus 54.62 0.00e+00 966.00
IUUC-Afl-008535 Aspergillus flavus 55.69 0.00e+00 911.00
IUUC-Afu-008845 Aspergillus fumigatus 54.22 0.00e+00 943.00
IUUC-Ani-009135 Aspergillus nidulans 55.95 0.00e+00 915.00
IUUC-Ang-009654 Aspergillus niger 56.18 0.00e+00 860.00
IUUC-Aor-009939 Aspergillus oryzae 53.64 0.00e+00 971.00
IUUC-Ate-010355 Aspergillus terreus 54.28 0.00e+00 917.00
IUUC-Ame-010922 Astyanax mexicanus 86.32 0.00e+00 1509.00
IUUC-Bgr-012249 Blumeria graminis 53.61 0.00e+00 932.00
IUUC-Bta-013579 Bos taurus 97.90 0.00e+00 1467.00
IUUC-Bci-013866 Botrytis cinerea 55.91 0.00e+00 931.00
IUUC-Bdi-015046 Brachypodium distachyon 61.33 0.00e+00 1114.00
IUUC-Bol-016271 Brassica oleracea 60.71 0.00e+00 1114.00
IUUC-Bra-016617 Brassica rapa 61.22 0.00e+00 1083.00
IUUC-Cel-018387 Caenorhabditis elegans 65.03 0.00e+00 1183.00
IUUC-Cja-019145 Callithrix jacchus 94.31 0.00e+00 1742.00
IUUC-Cfa-020564 Canis familiaris 94.09 0.00e+00 1733.00
IUUC-Cpo-022201 Cavia porcellus 97.51 0.00e+00 1728.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 58.91 0.00e+00 992.00
IUUC-Csa-023383 Chlorocebus sabaeus 97.88 0.00e+00 1174.00
IUUC-Cho-024454 Choloepus hoffmanni 91.70 0.00e+00 1397.00
IUUC-Cin-025681 Ciona intestinalis 78.17 0.00e+00 1373.00
IUUC-Csv-026012 Ciona savignyi 77.24 0.00e+00 1350.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 52.65 0.00e+00 849.00
IUUC-Cne-026986 Cryptococcus neoformans 51.69 0.00e+00 916.00
IUUC-Cme-027219 Cyanidioschyzon merolae 48.04 0.00e+00 852.00
IUUC-Dre-027846 Danio rerio 94.35 0.00e+00 1696.00
IUUC-Dor-030462 Dipodomys ordii 92.33 0.00e+00 1264.00
IUUC-Dse-031268 Dothistroma septosporum 54.79 0.00e+00 954.00
IUUC-Dme-031791 Drosophila melanogaster 71.67 0.00e+00 1280.00
IUUC-Ete-033166 Echinops telfairi 88.17 0.00e+00 1009.00
IUUC-Eca-034180 Equus caballus 94.79 0.00e+00 1672.00
IUUC-Eeu-035086 Erinaceus europaeus 78.92 0.00e+00 835.00
IUUC-Fca-036265 Felis catus 91.84 0.00e+00 1731.00
IUUC-Fal-037202 Ficedula albicollis 95.67 0.00e+00 1689.00
IUUC-Fox-037711 Fusarium oxysporum 56.77 0.00e+00 891.00
IUUC-Fso-038268 Fusarium solani 56.25 0.00e+00 889.00
IUUC-Gmo-039046 Gadus morhua 93.84 0.00e+00 1670.00
IUUC-Ggr-039863 Gaeumannomyces graminis 55.67 0.00e+00 909.00
IUUC-Gga-041112 Gallus gallus 98.35 0.00e+00 1749.00
IUUC-Gac-041733 Gasterosteus aculeatus 93.41 0.00e+00 1632.00
IUUC-Gma-042910 Glycine max 62.83 0.00e+00 1123.00
IUUC-Ggo-044984 Gorilla gorilla 93.98 0.00e+00 1737.00
IUUC-Hsa-046698 Homo sapiens 93.98 0.00e+00 1738.00
IUUC-Hvu-047669 Hordeum vulgare 71.19 3.00e-169 587.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 93.32 0.00e+00 1735.00
IUUC-Kpa-049265 Komagataella pastoris 49.32 0.00e+00 864.00
IUUC-Lch-050473 Latimeria chalumnae 92.49 0.00e+00 1724.00
IUUC-Lpe-051579 Leersia perrieri 61.17 0.00e+00 1102.00
IUUC-Loc-052675 Lepisosteus oculatus 95.53 0.00e+00 1713.00
IUUC-Lma-053218 Leptosphaeria maculans 54.72 0.00e+00 926.00
IUUC-Laf-053757 Loxodonta africana 93.44 0.00e+00 1729.00
IUUC-Mcc-054859 Macaca mulatta 94.42 0.00e+00 1744.00
IUUC-Meu-056174 Macropus eugenii 95.26 0.00e+00 748.00
IUUC-Mor-057264 Magnaporthe oryzae 55.97 0.00e+00 890.00
IUUC-Mpo-057538 Magnaporthe poae 56.03 0.00e+00 923.00
IUUC-Mtr-058310 Medicago truncatula 62.95 0.00e+00 1132.00
IUUC-Mla-058937 Melampsora laricipopulina 54.09 0.00e+00 914.00
IUUC-Mga-059875 Meleagris gallopavo 95.48 0.00e+00 1744.00
IUUC-Mvi-060240 Microbotryum violaceum 51.31 0.00e+00 909.00
IUUC-Mmr-061261 Microcebus murinus 92.64 0.00e+00 1741.00
IUUC-Mdo-062076 Monodelphis domestica 95.03 0.00e+00 1739.00
IUUC-Mmu-063324 Mus musculus 93.22 0.00e+00 1733.00
IUUC-Mac-064636 Musa acuminata 60.19 0.00e+00 1088.00
IUUC-Mpu-065961 Mustela putorius furo 97.75 0.00e+00 1733.00
IUUC-Mlu-067059 Myotis lucifugus 96.92 0.00e+00 1677.00
IUUC-Nfi-068277 Neosartorya fischeri 53.94 0.00e+00 932.00
IUUC-Ncr-068659 Neurospora crassa 53.01 0.00e+00 914.00
IUUC-Nle-069034 Nomascus leucogenys 94.42 0.00e+00 1746.00
IUUC-Opr-070334 Ochotona princeps 97.69 0.00e+00 1507.00
IUUC-Ont-071563 Oreochromis niloticus 94.00 0.00e+00 1686.00
IUUC-Oan-073416 Ornithorhynchus anatinus 97.31 0.00e+00 1653.00
IUUC-Ocu-074522 Oryctolagus cuniculus 92.42 0.00e+00 1734.00
IUUC-Oba-075760 Oryza barthii 59.62 0.00e+00 1082.00
IUUC-Obr-076201 Oryza brachyantha 61.26 0.00e+00 1108.00
IUUC-Ogl-077450 Oryza glaberrima 60.81 0.00e+00 1109.00
IUUC-Ogu-078994 Oryza glumaepatula 59.62 0.00e+00 1081.00
IUUC-Oin-079856 Oryza indica 60.29 0.00e+00 1083.00
IUUC-Olo-080731 Oryza longistaminata 58.93 0.00e+00 1065.00
IUUC-Ome-081554 Oryza meridionalis 57.11 0.00e+00 1006.00
IUUC-Oni-082324 Oryza nivara 59.62 0.00e+00 1081.00
IUUC-Opu-083400 Oryza punctata 58.89 0.00e+00 1072.00
IUUC-Oru-084829 Oryza rufipogon 59.62 0.00e+00 1082.00
IUUC-Osa-086026 Oryza sativa 60.81 0.00e+00 1112.00
IUUC-Ola-087245 Oryzias latipes 93.76 0.00e+00 1683.00
IUUC-Olu-087655 Ostreococcus lucimarinus 60.22 0.00e+00 1060.00
IUUC-Oga-088163 Otolemur garnettii 91.15 0.00e+00 1669.00
IUUC-Oar-089842 Ovis aries 97.16 0.00e+00 1726.00
IUUC-Ptr-090501 Pan troglodytes 92.73 0.00e+00 1741.00
IUUC-Pan-092011 Papio anubis 94.42 0.00e+00 1745.00
IUUC-Pma-094695 Petromyzon marinus 81.88 0.00e+00 1445.00
IUUC-Pno-094785 Phaeosphaeria nodorum 62.07 4.00e-112 398.00
IUUC-Ppa-095911 Physcomitrella patens 62.15 0.00e+00 1137.00
IUUC-Pfo-096587 Poecilia formosa 93.76 0.00e+00 1690.00
IUUC-Pab-097926 Pongo abelii 91.40 0.00e+00 1649.00
IUUC-Pop-099634 Populus trichocarpa 62.35 0.00e+00 1108.00
IUUC-Pca-100965 Procavia capensis 91.79 0.00e+00 1686.00
IUUC-Ppe-101470 Prunus persica 62.71 0.00e+00 1120.00
IUUC-Pva-102451 Pteropus vampyrus 91.43 0.00e+00 1257.00
IUUC-Pgr-103453 Puccinia graminis 54.42 0.00e+00 927.00
IUUC-Ptt-103868 Puccinia triticina 54.55 0.00e+00 926.00
IUUC-Pte-104274 Pyrenophora teres 55.51 0.00e+00 956.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 54.80 0.00e+00 907.00
IUUC-Rno-105979 Rattus norvegicus 83.45 0.00e+00 1249.00
IUUC-Sce-106269 Saccharomyces cerevisiae 47.55 0.00e+00 785.00
IUUC-Sha-106905 Sarcophilus harrisii 97.06 0.00e+00 1737.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.09 0.00e+00 830.00
IUUC-Spo-108299 Schizosaccharomyces pombe 47.41 0.00e+00 834.00
IUUC-Smo-108695 Selaginella moellendorffii 61.98 0.00e+00 1078.00
IUUC-Sit-110692 Setaria italica 62.35 0.00e+00 1107.00
IUUC-Sly-111775 Solanum lycopersicum 60.91 0.00e+00 1099.00
IUUC-Stu-112906 Solanum tuberosum 60.56 0.00e+00 994.00
IUUC-Sar-113472 Sorex araneus 90.29 0.00e+00 1147.00
IUUC-Sbi-113801 Sorghum bicolor 61.73 0.00e+00 1108.00
IUUC-Sre-115040 Sporisorium reilianum 52.50 0.00e+00 915.00
IUUC-Ssc-115593 Sus scrofa 94.09 0.00e+00 1741.00
IUUC-Tgu-117239 Taeniopygia guttata 95.69 0.00e+00 1744.00
IUUC-Tru-118025 Takifugu rubripes 93.88 0.00e+00 1682.00
IUUC-Tsy-118824 Tarsius syrichta 90.13 0.00e+00 1162.00
IUUC-Tni-120142 Tetraodon nigroviridis 93.62 0.00e+00 1674.00
IUUC-Tca-121613 Theobroma cacao 61.86 0.00e+00 1112.00
IUUC-Tre-122072 Trichoderma reesei 55.49 0.00e+00 938.00
IUUC-Tvi-122546 Trichoderma virens 54.99 0.00e+00 924.00
IUUC-Tae-125321 Triticum aestivum 60.66 0.00e+00 1096.00
IUUC-Tur-126283 Triticum urartu 53.89 0.00e+00 941.00
IUUC-Tme-127041 Tuber melanosporum 56.91 0.00e+00 980.00
IUUC-Tbe-127770 Tupaia belangeri 91.57 0.00e+00 1263.00
IUUC-Ttr-129294 Tursiops truncatus 92.52 0.00e+00 1734.00
IUUC-Uma-129351 Ustilago maydis 51.16 0.00e+00 907.00
IUUC-Vda-129716 Verticillium dahliae 55.61 0.00e+00 957.00
IUUC-Vpa-130037 Vicugna pacos 83.15 0.00e+00 871.00
IUUC-Vvi-131689 Vitis vinifera 61.49 0.00e+00 1115.00
IUUC-Xtr-132633 Xenopus tropicalis 94.91 0.00e+00 1686.00
IUUC-Xma-133347 Xiphophorus maculatus 94.00 0.00e+00 1691.00
IUUC-Yli-134455 Yarrowia lipolytica 50.64 0.00e+00 841.00
IUUC-Zma-135706 Zea mays 62.20 0.00e+00 1127.00
Created Date 25-Jun-2017

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