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Tag Content
iUUCD ID IUUC-Tru-118025
Ensembl Protein ID ENSTRUP00000000965.1
UniProt Accession H2RLF2; H2RLF2_TAKRU
Protein Name Coatomer subunit beta'
Gene Name copb2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTRUG00000000411.1 ENSTRUT00000000968.1 ENSTRUP00000000965.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.70e-34 115.7 183 224
UBD/Beta-Prp 9.40e-73 246.2 13 290
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 190  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVC 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 279  GLRGSNNVALGY 290
           *99999887544 PP
   
Organism Takifugu rubripes
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRR LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tru-118025|E3,WD_repeat;UBD,Beta-Prp|Takifugu rubripes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTATTCTGA CAGCACGAGG ATAAAATATG GTGAGAGACA ACGAAATACC CTAAATCCAC 60
TATTAGTGCC TTAAATGCGA CCGAGTCTTC CTTTCTAACC CTTAAATGTT TCATTATTAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tru-118025|E3,WD_repeat;UBD,Beta-Prp|Takifugu rubripes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
GO:0061053--P:somite development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 52.69 0.00e+00 923.00
IUUC-Aml-002154 Ailuropoda melanoleuca 86.72 0.00e+00 1664.00
IUUC-Atr-003090 Amborella trichopoda 58.08 0.00e+00 1060.00
IUUC-Apl-003976 Anas platyrhynchos 92.30 0.00e+00 1679.00
IUUC-Aca-004301 Anolis carolinensis 93.62 0.00e+00 1672.00
IUUC-Aly-006508 Arabidopsis lyrata 60.55 0.00e+00 1085.00
IUUC-Ath-007630 Arabidopsis thaliana 61.19 0.00e+00 1099.00
IUUC-Ago-007914 Ashbya gossypii 46.18 0.00e+00 749.00
IUUC-Acl-008237 Aspergillus clavatus 56.18 0.00e+00 956.00
IUUC-Afl-008535 Aspergillus flavus 52.80 0.00e+00 903.00
IUUC-Afu-008845 Aspergillus fumigatus 52.72 0.00e+00 931.00
IUUC-Ani-009135 Aspergillus nidulans 55.13 0.00e+00 908.00
IUUC-Ang-009654 Aspergillus niger 55.67 0.00e+00 850.00
IUUC-Aor-009939 Aspergillus oryzae 53.28 0.00e+00 962.00
IUUC-Ate-010355 Aspergillus terreus 53.36 0.00e+00 909.00
IUUC-Ame-010922 Astyanax mexicanus 86.04 0.00e+00 1527.00
IUUC-Bgr-012249 Blumeria graminis 52.83 0.00e+00 912.00
IUUC-Bta-013579 Bos taurus 94.96 0.00e+00 1436.00
IUUC-Bci-013866 Botrytis cinerea 55.17 0.00e+00 915.00
IUUC-Bdi-015046 Brachypodium distachyon 60.48 0.00e+00 1095.00
IUUC-Bol-016271 Brassica oleracea 60.92 0.00e+00 1102.00
IUUC-Bra-017758 Brassica rapa 60.07 0.00e+00 1102.00
IUUC-Cel-018387 Caenorhabditis elegans 64.18 0.00e+00 1166.00
IUUC-Cja-019145 Callithrix jacchus 87.49 0.00e+00 1668.00
IUUC-Cfa-020564 Canis familiaris 87.49 0.00e+00 1663.00
IUUC-Cpo-022201 Cavia porcellus 88.94 0.00e+00 1659.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 59.13 0.00e+00 986.00
IUUC-Csa-023383 Chlorocebus sabaeus 94.01 0.00e+00 1140.00
IUUC-Cho-024454 Choloepus hoffmanni 88.32 0.00e+00 1360.00
IUUC-Cin-025681 Ciona intestinalis 76.41 0.00e+00 1362.00
IUUC-Csv-026012 Ciona savignyi 76.96 0.00e+00 1341.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 50.67 0.00e+00 834.00
IUUC-Cne-026986 Cryptococcus neoformans 50.85 0.00e+00 905.00
IUUC-Cme-027219 Cyanidioschyzon merolae 45.95 0.00e+00 850.00
IUUC-Dre-027846 Danio rerio 94.53 0.00e+00 1709.00
IUUC-Dor-030462 Dipodomys ordii 89.04 0.00e+00 1234.00
IUUC-Dse-031268 Dothistroma septosporum 54.59 0.00e+00 943.00
IUUC-Dme-031791 Drosophila melanogaster 72.18 0.00e+00 1264.00
IUUC-Ete-033166 Echinops telfairi 84.79 0.00e+00 980.00
IUUC-Eca-034180 Equus caballus 86.72 0.00e+00 1604.00
IUUC-Eeu-035086 Erinaceus europaeus 74.21 0.00e+00 782.00
IUUC-Fca-036265 Felis catus 86.84 0.00e+00 1668.00
IUUC-Fal-037202 Ficedula albicollis 92.50 0.00e+00 1623.00
IUUC-Fox-037711 Fusarium oxysporum 55.21 0.00e+00 874.00
IUUC-Fso-038268 Fusarium solani 55.45 0.00e+00 874.00
IUUC-Gmo-039046 Gadus morhua 95.62 0.00e+00 1698.00
IUUC-Ggr-039863 Gaeumannomyces graminis 53.09 0.00e+00 891.00
IUUC-Gga-041112 Gallus gallus 92.19 0.00e+00 1681.00
IUUC-Gac-041733 Gasterosteus aculeatus 96.51 0.00e+00 1700.00
IUUC-Gma-042910 Glycine max 62.20 0.00e+00 1112.00
IUUC-Ggo-044984 Gorilla gorilla 87.17 0.00e+00 1662.00
IUUC-Hsa-046698 Homo sapiens 87.17 0.00e+00 1662.00
IUUC-Hvu-047669 Hordeum vulgare 70.34 6.00e-168 583.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 91.37 0.00e+00 1664.00
IUUC-Kpa-049265 Komagataella pastoris 49.19 0.00e+00 859.00
IUUC-Lch-050473 Latimeria chalumnae 88.77 0.00e+00 1698.00
IUUC-Lpe-051579 Leersia perrieri 61.10 0.00e+00 1083.00
IUUC-Loc-052675 Lepisosteus oculatus 93.30 0.00e+00 1703.00
IUUC-Lma-053218 Leptosphaeria maculans 53.43 0.00e+00 915.00
IUUC-Laf-053757 Loxodonta africana 87.39 0.00e+00 1661.00
IUUC-Mcc-054859 Macaca mulatta 87.49 0.00e+00 1667.00
IUUC-Meu-056174 Macropus eugenii 89.74 0.00e+00 706.00
IUUC-Mor-057264 Magnaporthe oryzae 53.57 0.00e+00 879.00
IUUC-Mpo-057538 Magnaporthe poae 53.33 0.00e+00 905.00
IUUC-Mtr-058310 Medicago truncatula 62.08 0.00e+00 1119.00
IUUC-Mla-058937 Melampsora laricipopulina 53.14 0.00e+00 897.00
IUUC-Mga-059875 Meleagris gallopavo 91.75 0.00e+00 1672.00
IUUC-Mvi-060240 Microbotryum violaceum 50.81 0.00e+00 905.00
IUUC-Mmr-061261 Microcebus murinus 87.81 0.00e+00 1673.00
IUUC-Mdo-062076 Monodelphis domestica 90.17 0.00e+00 1683.00
IUUC-Mmu-063324 Mus musculus 87.59 0.00e+00 1667.00
IUUC-Mac-064636 Musa acuminata 59.38 0.00e+00 1085.00
IUUC-Mpu-065961 Mustela putorius furo 87.38 0.00e+00 1667.00
IUUC-Mlu-067059 Myotis lucifugus 90.59 0.00e+00 1610.00
IUUC-Nfi-068277 Neosartorya fischeri 52.43 0.00e+00 920.00
IUUC-Ncr-068659 Neurospora crassa 52.70 0.00e+00 904.00
IUUC-Nle-069034 Nomascus leucogenys 87.59 0.00e+00 1669.00
IUUC-Opr-070334 Ochotona princeps 94.29 0.00e+00 1470.00
IUUC-Ont-071563 Oreochromis niloticus 92.60 0.00e+00 1743.00
IUUC-Oan-073416 Ornithorhynchus anatinus 92.94 0.00e+00 1590.00
IUUC-Ocu-074522 Oryctolagus cuniculus 87.49 0.00e+00 1667.00
IUUC-Oba-075760 Oryza barthii 60.42 0.00e+00 1063.00
IUUC-Obr-076201 Oryza brachyantha 60.64 0.00e+00 1092.00
IUUC-Ogl-077450 Oryza glaberrima 61.65 0.00e+00 1092.00
IUUC-Ogu-078994 Oryza glumaepatula 60.42 0.00e+00 1062.00
IUUC-Oin-079856 Oryza indica 60.12 0.00e+00 1065.00
IUUC-Olo-080731 Oryza longistaminata 59.21 0.00e+00 1051.00
IUUC-Ome-081762 Oryza meridionalis 56.07 0.00e+00 988.00
IUUC-Oni-082324 Oryza nivara 60.42 0.00e+00 1063.00
IUUC-Opu-083400 Oryza punctata 57.01 0.00e+00 1055.00
IUUC-Oru-084829 Oryza rufipogon 60.42 0.00e+00 1064.00
IUUC-Osa-086026 Oryza sativa 61.65 0.00e+00 1095.00
IUUC-Ola-087245 Oryzias latipes 91.79 0.00e+00 1748.00
IUUC-Olu-087655 Ostreococcus lucimarinus 59.53 0.00e+00 1046.00
IUUC-Oga-088163 Otolemur garnettii 84.40 0.00e+00 1602.00
IUUC-Oar-089842 Ovis aries 91.16 0.00e+00 1664.00
IUUC-Ptr-090501 Pan troglodytes 87.38 0.00e+00 1664.00
IUUC-Pan-092011 Papio anubis 87.59 0.00e+00 1669.00
IUUC-Psi-093308 Pelodiscus sinensis 93.88 0.00e+00 1679.00
IUUC-Pma-094695 Petromyzon marinus 80.99 0.00e+00 1429.00
IUUC-Pno-094785 Phaeosphaeria nodorum 61.38 1.00e-110 393.00
IUUC-Ppa-095911 Physcomitrella patens 61.18 0.00e+00 1118.00
IUUC-Pfo-096587 Poecilia formosa 90.91 0.00e+00 1751.00
IUUC-Pab-097926 Pongo abelii 85.32 0.00e+00 1572.00
IUUC-Pop-099634 Populus trichocarpa 61.36 0.00e+00 1105.00
IUUC-Pca-100965 Procavia capensis 89.05 0.00e+00 1617.00
IUUC-Ppe-101470 Prunus persica 61.71 0.00e+00 1108.00
IUUC-Pva-102451 Pteropus vampyrus 88.14 0.00e+00 1222.00
IUUC-Pgr-103453 Puccinia graminis 52.62 0.00e+00 913.00
IUUC-Ptt-103868 Puccinia triticina 52.50 0.00e+00 908.00
IUUC-Pte-104274 Pyrenophora teres 54.47 0.00e+00 948.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 53.77 0.00e+00 897.00
IUUC-Rno-105979 Rattus norvegicus 80.89 0.00e+00 1220.00
IUUC-Sce-106269 Saccharomyces cerevisiae 47.04 0.00e+00 786.00
IUUC-Sha-106905 Sarcophilus harrisii 91.73 0.00e+00 1679.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.03 0.00e+00 821.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.09 0.00e+00 815.00
IUUC-Smo-108828 Selaginella moellendorffii 61.82 0.00e+00 1074.00
IUUC-Sit-110692 Setaria italica 60.77 0.00e+00 1095.00
IUUC-Sly-111525 Solanum lycopersicum 61.84 0.00e+00 1111.00
IUUC-Stu-112906 Solanum tuberosum 60.26 0.00e+00 983.00
IUUC-Sar-113472 Sorex araneus 87.08 0.00e+00 1116.00
IUUC-Sbi-114052 Sorghum bicolor 62.64 0.00e+00 1108.00
IUUC-Sre-115040 Sporisorium reilianum 52.13 0.00e+00 908.00
IUUC-Ssc-115593 Sus scrofa 87.59 0.00e+00 1666.00
IUUC-Tgu-117239 Taeniopygia guttata 94.10 0.00e+00 1678.00
IUUC-Tsy-118824 Tarsius syrichta 86.65 0.00e+00 1127.00
IUUC-Tni-120142 Tetraodon nigroviridis 96.01 0.00e+00 1745.00
IUUC-Tca-121613 Theobroma cacao 61.47 0.00e+00 1103.00
IUUC-Tre-122072 Trichoderma reesei 53.21 0.00e+00 921.00
IUUC-Tvi-122546 Trichoderma virens 52.61 0.00e+00 907.00
IUUC-Tae-125292 Triticum aestivum 61.16 0.00e+00 1084.00
IUUC-Tur-126283 Triticum urartu 53.55 0.00e+00 923.00
IUUC-Tme-127041 Tuber melanosporum 56.59 0.00e+00 969.00
IUUC-Tbe-127770 Tupaia belangeri 88.72 0.00e+00 1232.00
IUUC-Ttr-129294 Tursiops truncatus 88.13 0.00e+00 1670.00
IUUC-Uma-129351 Ustilago maydis 50.00 0.00e+00 899.00
IUUC-Vda-129716 Verticillium dahliae 54.18 0.00e+00 941.00
IUUC-Vpa-130037 Vicugna pacos 75.74 0.00e+00 816.00
IUUC-Vvi-131689 Vitis vinifera 62.15 0.00e+00 1105.00
IUUC-Xtr-132633 Xenopus tropicalis 89.48 0.00e+00 1656.00
IUUC-Xma-133347 Xiphophorus maculatus 92.10 0.00e+00 1759.00
IUUC-Yli-134455 Yarrowia lipolytica 50.32 0.00e+00 833.00
IUUC-Zma-135867 Zea mays 62.52 0.00e+00 1107.00
Created Date 25-Jun-2017

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