iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066665

Ensembl Protein ID

ENSMPUP00000013228.1

UniProt Accession

M3YPH0; M3YPH0_MUSPF

Genbank Protein ID

ENSMPUP00000013228

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AEYP01074292

Gene Name

MARK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013326.1	ENSMPUT00000013439.1	ENSMPUP00000013228.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	98.31	0.00e+00	1536.00	IUUC-Hsa-046901

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MTAALWRKMN ARPTLGHLDP KPSSKSNMLR GRNSAASADE QPHIGNYRLL KTIGKGNFAK 60
VKLARHILTG KEVAVKIIDK TQLNSSSLQK LFREVRIMKV LNHPNIVKLF EVIETEKTLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAACTGGAG TGACCGGCTC AGAGGCTCCA AGCGGGGACT CAGCCCGCCT CACTGCCCCG 60
CATGACAGCA GCTCTCTGGA GGAAGATGAA TGCACGCGTG AGTATGTGAG CGCCGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005884--C:actin filament
GO:0016328--C:lateral plasma membrane
GO:0097427--C:microtubule bundle
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0003723--F:RNA binding
GO:0030010--P:establishment of cell polarity
GO:0045197--P:establishment or maintenance of epithelial cell apical/basal polarity
GO:0035556--P:intracellular signal transduction
GO:0000226--P:microtubule cytoskeleton organization
GO:0010976--P:positive regulation of neuron projection development
GO:0050770--P:regulation of axonogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004803	Anolis carolinensis	87.26	0.00e+00	1318.00
IUUC-Ame-011854	Astyanax mexicanus	71.20	0.00e+00	1061.00
IUUC-Cel-018198	Caenorhabditis elegans	73.55	3.00e-160	559.00
IUUC-Cja-019475	Callithrix jacchus	96.50	0.00e+00	1498.00
IUUC-Cfa-020356	Canis familiaris	98.96	0.00e+00	1542.00
IUUC-Cho-024317	Choloepus hoffmanni	59.11	6.00e-104	372.00
IUUC-Csv-026013	Ciona savignyi	56.88	1.00e-106	379.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	43.01	2.00e-69	257.00
IUUC-Dre-028467	Danio rerio	72.34	0.00e+00	1068.00
IUUC-Dno-029653	Dasypus novemcinctus	97.92	0.00e+00	1527.00
IUUC-Dor-030743	Dipodomys ordii	98.68	0.00e+00	1509.00
IUUC-Ete-032528	Echinops telfairi	96.61	0.00e+00	1244.00
IUUC-Eca-033799	Equus caballus	98.82	0.00e+00	1519.00
IUUC-Eeu-034949	Erinaceus europaeus	97.45	0.00e+00	948.00
IUUC-Fca-035596	Felis catus	98.96	0.00e+00	1546.00
IUUC-Gac-042044	Gasterosteus aculeatus	72.00	0.00e+00	1026.00
IUUC-Hsa-046901	Homo sapiens	98.31	0.00e+00	1536.00
IUUC-Lch-049551	Latimeria chalumnae	82.52	0.00e+00	1225.00
IUUC-Loc-051934	Lepisosteus oculatus	68.46	0.00e+00	982.00
IUUC-Mcc-055104	Macaca mulatta	98.18	0.00e+00	1533.00
IUUC-Meu-056525	Macropus eugenii	96.69	0.00e+00	1481.00
IUUC-Mmr-060697	Microcebus murinus	98.31	0.00e+00	1534.00
IUUC-Mmu-063467	Mus musculus	97.40	0.00e+00	1487.00
IUUC-Opr-070302	Ochotona princeps	96.37	0.00e+00	1494.00
IUUC-Pan-092847	Papio anubis	98.18	0.00e+00	1533.00
IUUC-Pfo-097451	Poecilia formosa	51.58	3.00e-107	382.00
IUUC-Pva-103239	Pteropus vampyrus	98.54	0.00e+00	1496.00
IUUC-Pgr-103687	Puccinia graminis	46.18	1.00e-70	261.00
IUUC-Ptt-103944	Puccinia triticina	44.73	7.00e-67	249.00
IUUC-Ssc-116439	Sus scrofa	93.97	0.00e+00	985.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence