iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066708

Ensembl Protein ID

ENSMPUP00000015287.1

UniProt Accession

M3YVC7; M3YVC7_MUSPF

Genbank Protein ID

ENSMPUP00000015287

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01027833

Gene Name

MLST8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000015397.1	ENSMPUT00000015526.1	ENSMPUP00000015287.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-32	109.0	221	251
UBD/Beta-Prp	5.10e-44	150.6	131	324

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht     ++f +d tll+++s D t+k+W++
   Q: 221  HTRYALQCRFsPDsTLLATCSADQTCKIWRT 251
           888888999**999***************96 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls........tgkcvhtlk 91
           ++i+cv+ +p++  l++g ++g i +wd++t    + + + e  +t+  ++pd+++++ + + ++ +vw+l         +  +  ++ 
   Q: 131  APINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTggigdevtQLIPKTKIP 219
           699****************************8886666999999*************************99988777643333333444 PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
           +h++++l ++fsp++  l++ s+d+t ++w +++ + + e       + +  +g+ ++ ++++d++++v++s D+  rlW+++tg++ r
   Q: 220  AHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTElsiksgnPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKR 308
           9*************************************99**9999999999************************************* PP
   S: 174  tltgghtdsvyslsfds 190
           +  g h+++v +l+f++
   Q: 309  EYGG-HQKAVVCLAFND 324
           **88.*********987 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

HTMNTSPGTV GSDPVILATA GYDHTVRFWQ AHSGICTRTV QHQDSVVNAL EITPDRSMIA 60
AAGYQHIRMY DLSSNNPNPI ISYDGVNKNI ASVGFHEDGR WMYTGGEDCT ARIWDLRSRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACACCATGA ACACGTCCCC TGGCACAGTG GGCAGTGACC CGGTGATCTT GGCCACTGCG 60
GGCTATGACC ACACGGTGCG GTTCTGGCAG GCCCACAGTG GGATCTGCAC GCGCACGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031931--C:TORC1 complex
GO:0031932--C:TORC2 complex
GO:0043539--F:protein serine/threonine kinase activator activity
GO:0030838--P:positive regulation of actin filament polymerization
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0032008--P:positive regulation of TOR signaling
GO:0043087--P:regulation of GTPase activity
GO:0038202--P:TORC1 signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000595	Aegilops tauschii	49.21	3.00e-83	301.00
IUUC-Aml-001813	Ailuropoda melanoleuca	99.69	0.00e+00	682.00
IUUC-Atr-002512	Amborella trichopoda	46.67	1.00e-78	286.00
IUUC-Apl-003495	Anas platyrhynchos	90.46	8.00e-153	532.00
IUUC-Aca-004613	Anolis carolinensis	93.87	0.00e+00	648.00
IUUC-Aly-006340	Arabidopsis lyrata	45.66	9.00e-79	286.00
IUUC-Ath-007273	Arabidopsis thaliana	45.34	5.00e-78	284.00
IUUC-Ago-007737	Ashbya gossypii	47.12	2.00e-81	295.00
IUUC-Acl-008090	Aspergillus clavatus	48.10	3.00e-59	222.00
IUUC-Afl-008490	Aspergillus flavus	41.84	1.00e-40	160.00
IUUC-Afu-009060	Aspergillus fumigatus	45.98	3.00e-52	199.00
IUUC-Ani-009251	Aspergillus nidulans	47.88	3.00e-59	222.00
IUUC-Ang-009528	Aspergillus niger	45.54	2.00e-75	275.00
IUUC-Aor-010005	Aspergillus oryzae	43.75	2.00e-68	251.00
IUUC-Ate-010423	Aspergillus terreus	48.52	2.00e-59	223.00
IUUC-Ame-011752	Astyanax mexicanus	91.72	0.00e+00	640.00
IUUC-Bgr-012299	Blumeria graminis	42.12	2.00e-69	255.00
IUUC-Bta-013007	Bos taurus	98.44	0.00e+00	662.00
IUUC-Bci-013987	Botrytis cinerea	43.08	1.00e-74	272.00
IUUC-Bdi-014082	Brachypodium distachyon	48.89	5.00e-83	300.00
IUUC-Bol-015088	Brassica oleracea	45.98	1.00e-78	286.00
IUUC-Bra-016682	Brassica rapa	41.02	2.00e-68	252.00
IUUC-Cel-018473	Caenorhabditis elegans	25.30	3.00e-35	142.00
IUUC-Cja-019216	Callithrix jacchus	98.88	9.00e-159	551.00
IUUC-Cfa-021229	Canis familiaris	99.39	0.00e+00	678.00
IUUC-Cpo-022270	Cavia porcellus	99.08	0.00e+00	677.00
IUUC-Cre-022742	Chlamydomonas reinhardtii	47.96	2.00e-83	302.00
IUUC-Csa-023275	Chlorocebus sabaeus	99.08	0.00e+00	677.00
IUUC-Cin-025588	Ciona intestinalis	63.49	1.00e-126	445.00
IUUC-Csv-026252	Ciona savignyi	64.67	1.00e-129	456.00
IUUC-Cgl-026418	Colletotrichum gloeosporioides	45.71	6.00e-76	277.00
IUUC-Cne-027013	Cryptococcus neoformans	43.45	2.00e-71	262.00
IUUC-Cme-027131	Cyanidioschyzon merolae	32.43	4.00e-50	191.00
IUUC-Dre-028424	Danio rerio	91.41	0.00e+00	639.00
IUUC-Dno-029327	Dasypus novemcinctus	98.77	0.00e+00	675.00
IUUC-Dor-030186	Dipodomys ordii	98.75	5.00e-93	334.00
IUUC-Dse-031475	Dothistroma septosporum	43.67	3.00e-73	268.00
IUUC-Dme-031826	Drosophila melanogaster	48.89	3.00e-92	331.00
IUUC-Ete-032252	Echinops telfairi	83.45	9.00e-139	486.00
IUUC-Eca-033889	Equus caballus	98.73	8.00e-140	489.00
IUUC-Fca-035989	Felis catus	99.08	0.00e+00	677.00
IUUC-Fal-036637	Ficedula albicollis	93.56	0.00e+00	648.00
IUUC-Fox-038066	Fusarium oxysporum	46.67	3.00e-79	288.00
IUUC-Fso-038288	Fusarium solani	44.44	3.00e-73	268.00
IUUC-Gmo-039477	Gadus morhua	92.21	0.00e+00	635.00
IUUC-Ggr-039990	Gaeumannomyces graminis	46.08	2.00e-76	279.00
IUUC-Gga-040890	Gallus gallus	93.56	0.00e+00	648.00
IUUC-Gac-041502	Gasterosteus aculeatus	91.41	0.00e+00	637.00
IUUC-Gma-042985	Glycine max	47.30	6.00e-80	290.00
IUUC-Ggo-045629	Gorilla gorilla	98.78	0.00e+00	674.00
IUUC-Hsa-045824	Homo sapiens	98.61	2.00e-171	594.00
IUUC-Hvu-047767	Hordeum vulgare	48.89	4.00e-83	301.00
IUUC-Itr-047932	Ictidomys tridecemlineatus	99.08	0.00e+00	677.00
IUUC-Kpa-049173	Komagataella pastoris	45.83	6.00e-81	293.00
IUUC-Lch-049703	Latimeria chalumnae	93.56	0.00e+00	647.00
IUUC-Lpe-050744	Leersia perrieri	44.76	6.00e-72	264.00
IUUC-Loc-052507	Lepisosteus oculatus	91.41	0.00e+00	637.00
IUUC-Lma-053084	Leptosphaeria maculans	43.77	1.00e-71	262.00
IUUC-Laf-053595	Loxodonta africana	97.85	0.00e+00	670.00
IUUC-Mcc-055634	Macaca mulatta	84.70	0.00e+00	640.00
IUUC-Meu-055925	Macropus eugenii	93.75	4.00e-164	570.00
IUUC-Mor-057131	Magnaporthe oryzae	43.57	1.00e-76	279.00
IUUC-Mpo-057524	Magnaporthe poae	45.77	2.00e-76	279.00
IUUC-Mtr-057980	Medicago truncatula	46.98	7.00e-80	290.00
IUUC-Mla-059082	Melampsora laricipopulina	38.73	5.00e-61	227.00
IUUC-Mga-059552	Meleagris gallopavo	91.84	1.00e-154	538.00
IUUC-Mvi-060504	Microbotryum violaceum	42.81	1.00e-68	254.00
IUUC-Mdo-062886	Monodelphis domestica	94.79	0.00e+00	652.00
IUUC-Mmu-063477	Mus musculus	97.55	0.00e+00	668.00
IUUC-Mac-065439	Musa acuminata	47.94	3.00e-81	295.00
IUUC-Mlu-067311	Myotis lucifugus	96.14	0.00e+00	666.00
IUUC-Nfi-068294	Neosartorya fischeri	45.81	9.00e-53	200.00
IUUC-Ncr-068811	Neurospora crassa	44.13	5.00e-74	270.00
IUUC-Nle-069632	Nomascus leucogenys	99.39	0.00e+00	679.00
IUUC-Opr-071128	Ochotona princeps	95.81	1.00e-108	385.00
IUUC-Ont-071494	Oreochromis niloticus	92.33	0.00e+00	642.00
IUUC-Oan-073298	Ornithorhynchus anatinus	92.59	2.00e-104	370.00
IUUC-Ocu-073983	Oryctolagus cuniculus	98.77	0.00e+00	673.00
IUUC-Oba-076001	Oryza barthii	44.44	9.00e-72	263.00
IUUC-Obr-076833	Oryza brachyantha	47.30	1.00e-79	290.00
IUUC-Ogl-077680	Oryza glaberrima	47.30	8.00e-80	290.00
IUUC-Ogu-078086	Oryza glumaepatula	43.33	8.00e-72	263.00
IUUC-Oin-079336	Oryza indica	47.30	8.00e-80	290.00
IUUC-Olo-080368	Oryza longistaminata	42.40	1.00e-58	219.00
IUUC-Oni-083046	Oryza nivara	44.44	9.00e-72	263.00
IUUC-Opu-084173	Oryza punctata	44.44	9.00e-72	263.00
IUUC-Oru-084599	Oryza rufipogon	44.44	9.00e-72	263.00
IUUC-Osa-086193	Oryza sativa	47.30	8.00e-80	290.00
IUUC-Ola-087216	Oryzias latipes	91.44	0.00e+00	642.00
IUUC-Olu-087852	Ostreococcus lucimarinus	46.67	5.00e-80	290.00
IUUC-Oga-088840	Otolemur garnettii	98.48	0.00e+00	673.00
IUUC-Oar-089294	Ovis aries	97.59	8.00e-172	595.00
IUUC-Ptr-090565	Pan troglodytes	99.39	0.00e+00	679.00
IUUC-Pan-092175	Papio anubis	99.08	0.00e+00	677.00
IUUC-Psi-093180	Pelodiscus sinensis	93.73	2.00e-156	544.00
IUUC-Pma-094705	Petromyzon marinus	82.52	2.00e-168	584.00
IUUC-Pno-095001	Phaeosphaeria nodorum	41.30	1.00e-61	229.00
IUUC-Ppa-095628	Physcomitrella patens	48.25	2.00e-82	299.00
IUUC-Pfo-097128	Poecilia formosa	91.41	0.00e+00	640.00
IUUC-Pab-098386	Pongo abelii	99.39	0.00e+00	679.00
IUUC-Pop-099064	Populus trichocarpa	47.62	1.00e-80	293.00
IUUC-Pca-100971	Procavia capensis	97.22	1.00e-169	588.00
IUUC-Ppe-101871	Prunus persica	47.62	2.00e-80	292.00
IUUC-Pva-102230	Pteropus vampyrus	77.89	8.00e-131	459.00
IUUC-Pgr-103511	Puccinia graminis	40.52	2.00e-63	236.00
IUUC-Ptt-103882	Puccinia triticina	37.57	4.00e-61	228.00
IUUC-Pte-104402	Pyrenophora teres	44.68	1.00e-72	266.00
IUUC-Pyt-104448	Pyrenophora triticirepentis	44.68	1.00e-72	266.00
IUUC-Rno-104880	Rattus norvegicus	97.55	0.00e+00	669.00
IUUC-Sce-106266	Saccharomyces cerevisiae	47.44	4.00e-83	301.00
IUUC-Sha-106966	Sarcophilus harrisii	94.79	0.00e+00	652.00
IUUC-Sja-107797	Schizosaccharomyces japonicus	46.62	1.00e-82	299.00
IUUC-Spo-108366	Schizosaccharomyces pombe	45.34	5.00e-82	297.00
IUUC-Smo-108749	Selaginella moellendorffii	46.84	2.00e-77	281.00
IUUC-Sit-110741	Setaria italica	48.89	3.00e-82	298.00
IUUC-Sly-111879	Solanum lycopersicum	42.44	4.00e-49	187.00
IUUC-Sbi-114551	Sorghum bicolor	48.89	3.00e-82	298.00
IUUC-Sre-114962	Sporisorium reilianum	39.12	3.00e-71	262.00
IUUC-Ssc-115363	Sus scrofa	98.18	0.00e+00	676.00
IUUC-Tgu-116695	Taeniopygia guttata	77.30	1.00e-142	499.00
IUUC-Tru-117999	Takifugu rubripes	89.94	0.00e+00	631.00
IUUC-Tni-119973	Tetraodon nigroviridis	90.49	0.00e+00	636.00
IUUC-Tca-121688	Theobroma cacao	47.15	8.00e-80	290.00
IUUC-Tre-122158	Trichoderma reesei	42.54	1.00e-73	269.00
IUUC-Tvi-122511	Trichoderma virens	44.83	2.00e-75	275.00
IUUC-Tae-124124	Triticum aestivum	49.21	4.00e-83	301.00
IUUC-Tur-126228	Triticum urartu	46.67	3.00e-75	275.00
IUUC-Tme-127100	Tuber melanosporum	47.91	1.00e-84	305.00
IUUC-Ttr-128216	Tursiops truncatus	97.94	1.00e-53	203.00
IUUC-Uma-129358	Ustilago maydis	40.34	9.00e-73	267.00
IUUC-Vda-129756	Verticillium dahliae	45.08	5.00e-77	280.00
IUUC-Vvi-131581	Vitis vinifera	46.03	2.00e-77	282.00
IUUC-Xtr-132363	Xenopus tropicalis	90.18	0.00e+00	627.00
IUUC-Xma-133857	Xiphophorus maculatus	91.41	0.00e+00	640.00
IUUC-Yli-134368	Yarrowia lipolytica	45.51	1.00e-78	286.00
IUUC-Zma-135854	Zea mays	48.89	2.00e-82	298.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence