iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019868

UUCD1 version

UUC-CaJ-01109

Ensembl Protein ID

ENSCJAP00000037840.2

UniProt Accession

F6ZVE0; F6ZVE0_CALJA

Genbank Protein ID

JAB22128.1; JAB22129.1; JAB27647.1; JAB27648.1; JAB35616.1; JAB48533.1; JAB48534.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

ACFV01120132; GAMS01001007; GAMR01006285; GAMR01006284; GAMQ01006235; GAMP01004222; GAMP01004221

Gene Name

USP20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000020348.2	ENSCJAT00000039967.2	ENSCJAP00000037840.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.70e-111	372.2	145	684

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tG+kNlgN+CYmN++LQ+Lsn+p+l++++le     +    ++++k +l+ks+qkl++e+w k++ ++v p++l + +k ++++f+gy+
   Q: 145  TGMKNLGNSCYMNAALQALSNCPPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVSEVWhKKRPSYVVPTSLSHGIKLVNPMFRGYA 228
           7******************************.....999999*******************99999*********************** PP
   S: 89   qqDaqEflaflldqleeelkk..eknkpkeeeeeedkselsde.............................................. 129
           qqD+qEfl++l+dql+eelk+   ++ + +e++++d+s+++++                                              
   Q: 229  QQDTQEFLRCLMDQLHEELKEpaVATVTLMEARDSDSSDTDEKregdrspsedeflscdsssdrgegdgqgrggansqaemellipeea 317
           *******************99884444444444444444444466666666666*********************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 318  graisekermkdrkfswgqqrtnseqvdedadvdtamaalddqpeeaqpltprstspcrtpepdndahlrsssrpcspvhhheghakls 406
           ***************************************************************************************** PP
   S: 130  ..........................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke....... 185
                                     ++++k++ ++s+isd+F+g++ s ++cl+cd+vs++ e+f+dlslp+pgke+ +k+       
   Q: 407  ssppraspvrtapsyvlkkaqvssagSRRRKEQCYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLhsaiyqn 495
           **************************99*************************************************99888******* PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLil 232
                                                     +l+dcL++f++++el+g+n+y+ce+ckk+++ +k +k+ +lPe+L++
   Q: 496  vpakpgtcgdsyatqgwlafiveyirrfvvsctpswfwgpviTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCI 584
           ***************************************************************************************** PP
   S: 233  hLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevke 319
           hLkRf  ++e + + kin++v+fple Ldl+pf+++++++q   ++Y+L++v++H+G+++sGHY+ay++n  +g+W++fdD++Vtev+e
   Q: 585  HLKRF--RHEVMYSFKINSHVSFPLEgLDLRPFLAKECTSQ--ITTYDLLSVICHHGTAGSGHYIAYCQNvINGQWYEFDDQYVTEVHE 669
           *****..9999***************************999..9**************************78999************** PP
   S: 320  eevleetgstaYvlfYkr 337
           + v++   +++YvlfY++
   Q: 670  TVVQN---AEGYVLFYRK 684
           *****...********98 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MGDSRDLCPH LDSIGEVTKE DLLLKSKGTC QSCGVTGPNL WACLQVACPY VGCGESFADH 60
STIHAQTKKH NLTVNLTTFR LWCYACEKEV FLEQRLVAPL PGSSSTFSEQ DSPPPSHPLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGGGGGC GCGCTTGACT GACAGGCGGC GGCGGCGCCG TTGCTAGTGC AGGTGAGTTC 60
AGGGCCGCCA CCGGCCGCTT CTGTGGGCCG GGCCTCTCCG AGCTTGGGCG ACCCCAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP

SMART

SM00695--DUSP
SM00290--ZnF_UBP

Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cjc:100394310

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002209	Ailuropoda melanoleuca	91.48	0.00e+00	1657.00
IUUC-Apl-003351	Anas platyrhynchos	85.45	0.00e+00	1563.00
IUUC-Aca-005077	Anolis carolinensis	76.12	0.00e+00	1107.00
IUUC-Ame-011777	Astyanax mexicanus	75.14	0.00e+00	1342.00
IUUC-Bta-013063	Bos taurus	92.90	0.00e+00	1659.00
IUUC-Cfa-020761	Canis familiaris	92.47	0.00e+00	1676.00
IUUC-Cpo-022267	Cavia porcellus	86.26	0.00e+00	1557.00
IUUC-Csa-024251	Chlorocebus sabaeus	96.72	0.00e+00	1778.00
IUUC-Cho-024483	Choloepus hoffmanni	96.23	3.00e-124	439.00
IUUC-Csv-025889	Ciona savignyi	43.71	1.00e-35	142.00
IUUC-Dre-028061	Danio rerio	74.17	0.00e+00	1208.00
IUUC-Dno-029423	Dasypus novemcinctus	94.54	0.00e+00	1708.00
IUUC-Dor-030877	Dipodomys ordii	91.33	0.00e+00	1087.00
IUUC-Dme-031837	Drosophila melanogaster	43.84	4.00e-137	482.00
IUUC-Ete-032802	Echinops telfairi	81.71	2.00e-138	486.00
IUUC-Eca-034283	Equus caballus	91.81	0.00e+00	1659.00
IUUC-Eeu-034620	Erinaceus europaeus	89.04	0.00e+00	1172.00
IUUC-Fca-036357	Felis catus	93.01	0.00e+00	1668.00
IUUC-Fal-037411	Ficedula albicollis	85.76	0.00e+00	1564.00
IUUC-Gga-041101	Gallus gallus	85.48	0.00e+00	1549.00
IUUC-Gac-041315	Gasterosteus aculeatus	73.89	0.00e+00	1317.00
IUUC-Ggo-045600	Gorilla gorilla	96.52	0.00e+00	1729.00
IUUC-Hsa-045825	Homo sapiens	97.16	0.00e+00	1742.00
IUUC-Itr-048549	Ictidomys tridecemlineatus	81.84	0.00e+00	1405.00
IUUC-Lch-050002	Latimeria chalumnae	76.67	0.00e+00	1329.00
IUUC-Loc-052574	Lepisosteus oculatus	77.37	0.00e+00	1416.00
IUUC-Laf-054428	Loxodonta africana	92.92	0.00e+00	1676.00
IUUC-Mcc-055736	Macaca mulatta	96.50	0.00e+00	1773.00
IUUC-Mga-059781	Meleagris gallopavo	84.83	0.00e+00	1545.00
IUUC-Mdo-063048	Monodelphis domestica	86.49	0.00e+00	1527.00
IUUC-Mmu-064079	Mus musculus	91.71	0.00e+00	1657.00
IUUC-Mpu-066616	Mustela putorius furo	91.72	0.00e+00	1709.00
IUUC-Mlu-067294	Myotis lucifugus	91.05	0.00e+00	1602.00
IUUC-Nle-070015	Nomascus leucogenys	96.72	0.00e+00	1703.00
IUUC-Opr-070328	Ochotona princeps	92.69	0.00e+00	1689.00
IUUC-Ont-071464	Oreochromis niloticus	73.78	0.00e+00	1310.00
IUUC-Oan-073259	Ornithorhynchus anatinus	79.01	0.00e+00	1305.00
IUUC-Ocu-074630	Oryctolagus cuniculus	90.39	0.00e+00	1607.00
IUUC-Ola-087240	Oryzias latipes	74.76	0.00e+00	1298.00
IUUC-Oga-088761	Otolemur garnettii	93.33	0.00e+00	1711.00
IUUC-Oar-089490	Ovis aries	87.76	0.00e+00	1499.00
IUUC-Ptr-091662	Pan troglodytes	97.16	0.00e+00	1741.00
IUUC-Pan-092199	Papio anubis	96.29	0.00e+00	1767.00
IUUC-Psi-093726	Pelodiscus sinensis	86.49	0.00e+00	1566.00
IUUC-Pma-094389	Petromyzon marinus	62.79	8.00e-100	356.00
IUUC-Pab-098632	Pongo abelii	96.94	0.00e+00	1732.00
IUUC-Pca-100614	Procavia capensis	85.89	0.00e+00	1302.00
IUUC-Pva-102922	Pteropus vampyrus	90.71	0.00e+00	973.00
IUUC-Rno-105215	Rattus norvegicus	91.48	0.00e+00	1659.00
IUUC-Sha-106601	Sarcophilus harrisii	85.84	0.00e+00	1514.00
IUUC-Ssc-115533	Sus scrofa	91.25	0.00e+00	1635.00
IUUC-Tgu-117364	Taeniopygia guttata	85.93	0.00e+00	1538.00
IUUC-Tru-117770	Takifugu rubripes	72.64	0.00e+00	1293.00
IUUC-Tni-120001	Tetraodon nigroviridis	73.25	0.00e+00	1277.00
IUUC-Ttr-128732	Tursiops truncatus	93.12	0.00e+00	1671.00
IUUC-Xtr-132157	Xenopus tropicalis	76.91	0.00e+00	1362.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence