iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000025462.7	ENSRNOT00000067022.4	ENSRNOP00000061347.2
ENSRNOG00000025462.7	ENSRNOT00000036748.5	ENSRNOP00000031387.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-22	77.4	82	127

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl.af........sdtllvsGsdDgtikvWDlrtgvllk 37
           gHt ++t++  f        s+ ll+++s D t+ vWD +tg++++
   Q: 82   GHTQKITAViTFlpldsceaSSQLLLTASADRTVGVWDCDTGRQIQ 127
           8*******7269***999986699******************9986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MLRWLIGGGR EPQGLAEKAA LQTIGEDQGQ NPYTELLVLK AHRDIVRFLV QLDGYRFASA 60
GDDGIIVVWN AQTGEKLLEL RGHTQKITAV ITFLPLDSCE ASSQLLLTAS ADRTVGVWDC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGCCAACC GCGAGGCACC CACGCGCGTG CTCGCTGGGG ACGCGGAACC TCCGCCTCCG 60
CTGCCGCCGC GGCCTTCTGT GAGGGCTCCC GAACTAGACT TCTGTTTTCT CGCTGCCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0032045--C:guanyl-nucleotide exchange factor complex
GO:0005765--C:lysosomal membrane
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001900	Ailuropoda melanoleuca	85.15	0.00e+00	815.00
IUUC-Apl-004087	Anas platyrhynchos	72.41	5.00e-177	613.00
IUUC-Aca-005359	Anolis carolinensis	68.64	0.00e+00	651.00
IUUC-Ame-010669	Astyanax mexicanus	41.08	2.00e-75	276.00
IUUC-Bta-013534	Bos taurus	82.24	0.00e+00	793.00
IUUC-Cja-019219	Callithrix jacchus	85.75	0.00e+00	795.00
IUUC-Cfa-020310	Canis familiaris	84.09	0.00e+00	783.00
IUUC-Cpo-021664	Cavia porcellus	84.21	0.00e+00	809.00
IUUC-Csa-024228	Chlorocebus sabaeus	86.40	0.00e+00	827.00
IUUC-Cho-024898	Choloepus hoffmanni	78.92	3.00e-103	369.00
IUUC-Dre-028538	Danio rerio	52.08	5.00e-126	444.00
IUUC-Dno-028861	Dasypus novemcinctus	82.31	0.00e+00	788.00
IUUC-Dor-030111	Dipodomys ordii	85.09	0.00e+00	805.00
IUUC-Ete-032444	Echinops telfairi	84.64	3.00e-156	545.00
IUUC-Eca-033676	Equus caballus	83.99	0.00e+00	806.00
IUUC-Eeu-034571	Erinaceus europaeus	75.44	0.00e+00	702.00
IUUC-Fca-035387	Felis catus	85.59	0.00e+00	815.00
IUUC-Fal-037310	Ficedula albicollis	71.23	0.00e+00	655.00
IUUC-Gmo-039224	Gadus morhua	51.84	3.00e-126	445.00
IUUC-Gga-040957	Gallus gallus	73.35	0.00e+00	678.00
IUUC-Gac-042385	Gasterosteus aculeatus	52.19	2.00e-135	475.00
IUUC-Ggo-044973	Gorilla gorilla	85.62	0.00e+00	817.00
IUUC-Hsa-046842	Homo sapiens	86.18	0.00e+00	823.00
IUUC-Itr-048784	Ictidomys tridecemlineatus	87.15	4.00e-168	583.00
IUUC-Lch-049625	Latimeria chalumnae	60.66	3.00e-167	581.00
IUUC-Loc-052368	Lepisosteus oculatus	56.80	2.00e-150	525.00
IUUC-Laf-053678	Loxodonta africana	82.71	0.00e+00	788.00
IUUC-Mcc-055184	Macaca mulatta	85.07	0.00e+00	789.00
IUUC-Meu-056165	Macropus eugenii	71.46	0.00e+00	645.00
IUUC-Mga-060184	Meleagris gallopavo	70.89	3.00e-62	230.00
IUUC-Mmr-060965	Microcebus murinus	85.09	0.00e+00	813.00
IUUC-Mdo-062702	Monodelphis domestica	80.00	0.00e+00	770.00
IUUC-Mmu-063649	Mus musculus	93.33	4.00e-133	468.00
IUUC-Mpu-065747	Mustela putorius furo	84.65	0.00e+00	811.00
IUUC-Mlu-067873	Myotis lucifugus	84.50	0.00e+00	807.00
IUUC-Nle-069670	Nomascus leucogenys	86.62	0.00e+00	824.00
IUUC-Opr-070266	Ochotona princeps	76.04	0.00e+00	714.00
IUUC-Ont-071242	Oreochromis niloticus	51.32	7.00e-132	463.00
IUUC-Oan-072879	Ornithorhynchus anatinus	78.86	0.00e+00	733.00
IUUC-Ocu-074872	Oryctolagus cuniculus	64.57	8.00e-156	543.00
IUUC-Ola-087211	Oryzias latipes	48.47	1.00e-113	402.00
IUUC-Oga-088852	Otolemur garnettii	84.21	0.00e+00	809.00
IUUC-Oar-089812	Ovis aries	82.24	0.00e+00	791.00
IUUC-Ptr-091067	Pan troglodytes	86.40	0.00e+00	826.00
IUUC-Pan-091778	Papio anubis	85.56	0.00e+00	817.00
IUUC-Psi-093932	Pelodiscus sinensis	71.46	0.00e+00	668.00
IUUC-Pfo-096845	Poecilia formosa	51.96	9.00e-130	456.00
IUUC-Pab-097892	Pongo abelii	84.71	0.00e+00	727.00
IUUC-Pca-100567	Procavia capensis	61.18	8.00e-155	540.00
IUUC-Pva-102560	Pteropus vampyrus	82.24	0.00e+00	778.00
IUUC-Sha-107058	Sarcophilus harrisii	78.71	0.00e+00	747.00
IUUC-Sar-113643	Sorex araneus	72.67	0.00e+00	640.00
IUUC-Ssc-115791	Sus scrofa	84.43	0.00e+00	811.00
IUUC-Tgu-117145	Taeniopygia guttata	72.09	0.00e+00	660.00
IUUC-Tru-117875	Takifugu rubripes	52.85	4.00e-137	481.00
IUUC-Tsy-119030	Tarsius syrichta	83.24	0.00e+00	642.00
IUUC-Tni-119761	Tetraodon nigroviridis	51.20	8.00e-131	460.00
IUUC-Tbe-127757	Tupaia belangeri	84.50	0.00e+00	706.00
IUUC-Ttr-128762	Tursiops truncatus	85.75	0.00e+00	823.00
IUUC-Vpa-130360	Vicugna pacos	85.09	0.00e+00	816.00
IUUC-Xtr-131954	Xenopus tropicalis	61.49	7.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence