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Tag Content
iUUCD ID IUUC-Yli-134559
Ensembl Protein ID CAG78850
UniProt Accession Q6BZX5; SEC13_YARLI
Genbank Protein ID CAG78850.1
Protein Name Protein transport protein SEC13
Genbank Nucleotide ID CR382132
Gene Name SEC13; YALI0F30151g
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YALI0_F30151g CAG78850 CAG78850
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.70e-27 92.8 204 236
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvW 28
           gH+d+v+++a+     s  +++s+s D+t+ vW
   Q: 204  GHKDWVRDVAWsssvlSKSYIASASQDKTVIVW 236
           8***********99964489************* PP
   
Organism Yarrowia lipolytica
Functional Description
(View)

Functional Description


     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
 Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MVTIGNTHDD LIHDAVLDYY GKRLATCSSD KTIKIFEIDG DNHKLVETLR GHEGPVWQVS 60
WAHPKFGSII ASASYDGKVF IWREENGRWT NIAQHQHNAS VNSVVWAPQE YGPLLLCASS 120
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Protein Fasta Sequence


>IUUC-Yli-134559|E3,WD_repeat|Yarrowia lipolytica
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Nucleotide Sequence
(Fasta)
ATGGTGAGTA TGGAAACGAC AGCTATGATC CGGCAATCAG CTAACCCAGG TGACCATAGG 60
AAACACGCAC GACGACCTCA TCCACGACGC CGTCCTGGAC TACTACGGCA AGCGATTGGC 120
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Nucleotide Fasta Sequence


>IUUC-Yli-134559|E3,WD_repeat|Yarrowia lipolytica
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG yli:YALI0F30151g
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 50.33 2.00e-78 283.00
IUUC-Aml-001832 Ailuropoda melanoleuca 52.38 2.00e-84 303.00
IUUC-Atr-002914 Amborella trichopoda 50.66 6.00e-77 278.00
IUUC-Apl-003992 Anas platyrhynchos 53.52 1.00e-80 290.00
IUUC-Aca-005283 Anolis carolinensis 52.88 2.00e-83 300.00
IUUC-Aly-005654 Arabidopsis lyrata 49.17 3.00e-72 262.00
IUUC-Ath-006810 Arabidopsis thaliana 49.50 3.00e-72 263.00
IUUC-Ago-007827 Ashbya gossypii 66.45 9.00e-119 417.00
IUUC-Acl-008205 Aspergillus clavatus 61.07 3.00e-98 349.00
IUUC-Afl-008748 Aspergillus flavus 60.13 2.00e-98 349.00
IUUC-Afu-008791 Aspergillus fumigatus 60.74 1.00e-97 347.00
IUUC-Ani-009152 Aspergillus nidulans 62.05 5.00e-102 362.00
IUUC-Ang-009765 Aspergillus niger 61.13 5.00e-100 355.00
IUUC-Aor-009927 Aspergillus oryzae 59.60 2.00e-95 340.00
IUUC-Ate-010248 Aspergillus terreus 60.47 2.00e-99 353.00
IUUC-Ame-011478 Astyanax mexicanus 52.38 4.00e-83 299.00
IUUC-Bgr-012276 Blumeria graminis 57.69 6.00e-97 344.00
IUUC-Bta-012700 Bos taurus 53.06 5.00e-84 301.00
IUUC-Bci-013722 Botrytis cinerea 60.07 3.00e-98 349.00
IUUC-Bdi-014818 Brachypodium distachyon 50.33 6.00e-78 281.00
IUUC-Bol-015779 Brassica oleracea 49.17 5.00e-72 262.00
IUUC-Bra-016973 Brassica rapa 49.33 4.00e-73 267.00
IUUC-Cel-018479 Caenorhabditis elegans 39.66 1.00e-57 214.00
IUUC-Cja-019956 Callithrix jacchus 51.93 6.00e-79 285.00
IUUC-Cfa-020752 Canis familiaris 52.38 4.00e-84 302.00
IUUC-Cpo-021871 Cavia porcellus 54.24 7.00e-86 308.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 52.07 4.00e-82 295.00
IUUC-Csa-023393 Chlorocebus sabaeus 53.06 1.00e-84 304.00
IUUC-Cho-024786 Choloepus hoffmanni 38.91 1.00e-51 194.00
IUUC-Cin-025332 Ciona intestinalis 51.32 9.00e-82 294.00
IUUC-Csv-025926 Ciona savignyi 51.01 8.00e-81 291.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 62.80 1.00e-96 343.00
IUUC-Cne-027054 Cryptococcus neoformans 50.31 3.00e-79 286.00
IUUC-Cme-027165 Cyanidioschyzon merolae 36.86 2.00e-50 191.00
IUUC-Dre-027782 Danio rerio 52.04 3.00e-82 296.00
IUUC-Dno-029628 Dasypus novemcinctus 52.04 5.00e-84 302.00
IUUC-Dor-030650 Dipodomys ordii 50.65 1.00e-63 234.00
IUUC-Dse-031206 Dothistroma septosporum 56.67 3.00e-91 326.00
IUUC-Dme-031854 Drosophila melanogaster 50.00 4.00e-74 269.00
IUUC-Ete-032618 Echinops telfairi 42.27 2.00e-34 137.00
IUUC-Eca-033268 Equus caballus 52.72 4.00e-84 302.00
IUUC-Fca-035918 Felis catus 52.38 4.00e-84 302.00
IUUC-Fal-037551 Ficedula albicollis 52.45 6.00e-77 278.00
IUUC-Fox-037763 Fusarium oxysporum 59.80 4.00e-99 352.00
IUUC-Fso-038341 Fusarium solani 61.92 3.00e-100 355.00
IUUC-Gmo-038638 Gadus morhua 52.20 5.00e-83 298.00
IUUC-Ggr-039865 Gaeumannomyces graminis 58.09 2.00e-97 346.00
IUUC-Gga-040193 Gallus gallus 53.06 4.00e-84 302.00
IUUC-Gma-043518 Glycine max 51.01 4.00e-74 269.00
IUUC-Ggo-045252 Gorilla gorilla 53.06 8.00e-85 305.00
IUUC-Hsa-046565 Homo sapiens 53.06 1.00e-84 304.00
IUUC-Hvu-047835 Hordeum vulgare 51.49 2.00e-78 283.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 53.22 7.00e-84 301.00
IUUC-Kpa-049148 Komagataella pastoris 66.67 7.00e-118 414.00
IUUC-Lch-050421 Latimeria chalumnae 52.38 4.00e-83 299.00
IUUC-Lpe-051187 Leersia perrieri 49.50 2.00e-76 279.00
IUUC-Loc-052167 Lepisosteus oculatus 51.70 2.00e-83 300.00
IUUC-Lma-053250 Leptosphaeria maculans 58.90 3.00e-93 332.00
IUUC-Laf-054304 Loxodonta africana 52.04 3.00e-83 299.00
IUUC-Mcc-055519 Macaca mulatta 53.06 1.00e-84 304.00
IUUC-Meu-056439 Macropus eugenii 51.36 5.00e-83 298.00
IUUC-Mor-057241 Magnaporthe oryzae 59.73 3.00e-95 339.00
IUUC-Mpo-057373 Magnaporthe poae 52.38 1.00e-78 283.00
IUUC-Mtr-058412 Medicago truncatula 50.34 2.00e-73 266.00
IUUC-Mla-058966 Melampsora laricipopulina 50.30 3.00e-86 309.00
IUUC-Mga-060066 Meleagris gallopavo 53.52 1.00e-80 290.00
IUUC-Mvi-060290 Microbotryum violaceum 49.54 4.00e-83 301.00
IUUC-Mmr-060717 Microcebus murinus 52.38 6.00e-84 301.00
IUUC-Mdo-062496 Monodelphis domestica 51.02 1.00e-82 297.00
IUUC-Mmu-063490 Mus musculus 52.53 2.00e-84 303.00
IUUC-Mac-064519 Musa acuminata 49.83 3.00e-75 273.00
IUUC-Mpu-066601 Mustela putorius furo 52.38 4.00e-84 302.00
IUUC-Mlu-067501 Myotis lucifugus 52.04 1.00e-83 300.00
IUUC-Nfi-068360 Neosartorya fischeri 57.31 1.00e-76 277.00
IUUC-Ncr-068928 Neurospora crassa 61.06 4.00e-100 355.00
IUUC-Nle-069028 Nomascus leucogenys 52.72 1.00e-84 304.00
IUUC-Opr-070446 Ochotona princeps 53.17 3.00e-80 289.00
IUUC-Ont-071587 Oreochromis niloticus 52.38 9.00e-84 301.00
IUUC-Oan-073211 Ornithorhynchus anatinus 50.34 1.00e-81 294.00
IUUC-Ocu-074306 Oryctolagus cuniculus 51.02 4.00e-82 295.00
IUUC-Oba-075069 Oryza barthii 49.34 3.00e-76 276.00
IUUC-Obr-076667 Oryza brachyantha 50.00 3.00e-77 279.00
IUUC-Ogl-077208 Oryza glaberrima 49.34 3.00e-76 276.00
IUUC-Ogu-078513 Oryza glumaepatula 49.34 3.00e-76 276.00
IUUC-Oin-079094 Oryza indica 49.34 3.00e-76 276.00
IUUC-Olo-080473 Oryza longistaminata 49.34 3.00e-76 276.00
IUUC-Ome-081643 Oryza meridionalis 49.34 3.00e-76 276.00
IUUC-Oni-082589 Oryza nivara 49.34 3.00e-76 276.00
IUUC-Opu-083677 Oryza punctata 49.67 2.00e-76 276.00
IUUC-Oru-084537 Oryza rufipogon 49.34 3.00e-76 276.00
IUUC-Osa-085449 Oryza sativa 49.34 3.00e-76 276.00
IUUC-Ola-087226 Oryzias latipes 52.04 4.00e-83 299.00
IUUC-Olu-087893 Ostreococcus lucimarinus 46.37 2.00e-66 243.00
IUUC-Oga-088837 Otolemur garnettii 52.38 2.00e-84 303.00
IUUC-Oar-089594 Ovis aries 52.38 6.00e-84 301.00
IUUC-Ptr-091132 Pan troglodytes 53.06 3.00e-85 305.00
IUUC-Psi-093568 Pelodiscus sinensis 52.80 2.00e-80 290.00
IUUC-Pma-094756 Petromyzon marinus 53.77 3.00e-31 124.00
IUUC-Pno-094955 Phaeosphaeria nodorum 58.42 7.00e-93 331.00
IUUC-Ppa-095966 Physcomitrella patens 52.56 4.00e-72 262.00
IUUC-Pfo-096063 Poecilia formosa 52.72 1.00e-83 300.00
IUUC-Pab-098674 Pongo abelii 53.40 2.00e-85 306.00
IUUC-Pop-099402 Populus trichocarpa 48.67 2.00e-73 266.00
IUUC-Pca-100824 Procavia capensis 40.96 1.00e-59 221.00
IUUC-Ppe-101278 Prunus persica 49.00 1.00e-72 264.00
IUUC-Pva-103161 Pteropus vampyrus 48.98 2.00e-76 276.00
IUUC-Pgr-103573 Puccinia graminis 52.85 1.00e-90 324.00
IUUC-Ptt-103700 Puccinia triticina 53.53 5.00e-86 308.00
IUUC-Pte-104267 Pyrenophora teres 57.00 5.00e-89 318.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 57.34 2.00e-85 306.00
IUUC-Rno-104833 Rattus norvegicus 52.54 6.00e-84 301.00
IUUC-Sce-106437 Saccharomyces cerevisiae 65.33 1.00e-110 390.00
IUUC-Sha-106611 Sarcophilus harrisii 51.36 5.00e-83 298.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 58.13 6.00e-100 355.00
IUUC-Spo-108362 Schizosaccharomyces pombe 59.23 3.00e-103 365.00
IUUC-Smo-108797 Selaginella moellendorffii 49.83 2.00e-76 276.00
IUUC-Sit-110132 Setaria italica 50.33 3.00e-77 279.00
IUUC-Sly-111852 Solanum lycopersicum 48.53 3.00e-72 262.00
IUUC-Stu-112195 Solanum tuberosum 48.86 5.00e-73 265.00
IUUC-Sbi-114229 Sorghum bicolor 50.66 5.00e-78 281.00
IUUC-Sre-114898 Sporisorium reilianum 48.39 4.00e-83 299.00
IUUC-Ssc-115995 Sus scrofa 52.67 3.00e-44 168.00
IUUC-Tgu-116793 Taeniopygia guttata 52.04 3.00e-79 286.00
IUUC-Tru-117797 Takifugu rubripes 51.70 1.00e-82 297.00
IUUC-Tni-120366 Tetraodon nigroviridis 52.04 2.00e-83 300.00
IUUC-Tca-121068 Theobroma cacao 49.32 1.00e-72 264.00
IUUC-Tre-121899 Trichoderma reesei 61.00 2.00e-98 350.00
IUUC-Tvi-122380 Trichoderma virens 61.20 9.00e-99 350.00
IUUC-Tae-123998 Triticum aestivum 51.32 3.00e-79 286.00
IUUC-Tur-126202 Triticum urartu 50.66 2.00e-78 283.00
IUUC-Tme-127181 Tuber melanosporum 61.02 3.00e-107 379.00
IUUC-Ttr-128448 Tursiops truncatus 51.84 2.00e-65 240.00
IUUC-Uma-129661 Ustilago maydis 49.26 8.00e-85 305.00
IUUC-Vda-129666 Verticillium dahliae 60.41 1.00e-95 340.00
IUUC-Vpa-130318 Vicugna pacos 52.38 5.00e-84 302.00
IUUC-Vvi-130868 Vitis vinifera 50.33 8.00e-75 271.00
IUUC-Xtr-131859 Xenopus tropicalis 52.04 2.00e-82 297.00
IUUC-Xma-133898 Xiphophorus maculatus 52.72 7.00e-84 301.00
Created Date 25-Jun-2017

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