iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115458

Ensembl Protein ID

ENSSSCP00000001146.2

UniProt Accession

F1RUH4; F1RUH4_PIG

Genbank Protein ID

ENSSSCP00000001146

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU468186

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000001076.2	ENSSSCT00000001171.2	ENSSSCP00000001146.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.90e-50	172.1	34	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 34   CKLCLCEQSLDKMTTLQECRCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPCR 122
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck++wH+++sCke +  +  te   + +   + +ea +k+Cp C+vyie+neg
   Q: 123  TWCPVADCQTVCPVASSDpgQPVLVECPSCHLKFCSCCKDAWHAEVSCKESQPVVLPTE---HGTLFGTEAEAPIKQCPVCRVYIERNEG 209
           *************9998877899999*****************************9999...8899999********************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 210  CAQMMCKNCKHTFCWYC 226
           ***************** PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSSVGSLHYL TMTAENPAEN PTPGDLALTP LVTCKLCLCE QSLDKMTTLQ ECRCIFCTAC 60
LKQYMQLAIR EGCGSPITCP DMVCLNHGTL QEAEIACLVP VDQFQLYQRL KFEREVHLDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCAGAAG TAGGTATCCC AGAAGGACAA GAGAGAAGTC CTGATAAGTG GAGCGAGTGC 60
AGGAGAGCTG GGCGCGCCGA TAGCCAGGTT CGGACAGGGT TAAGACCATC ACCTGCCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ssc:100155665

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	91.53	7.00e-161	559.00
IUUC-Atr-002709	Amborella trichopoda	29.15	2.00e-18	87.40
IUUC-Apl-004112	Anas platyrhynchos	81.75	7.00e-130	456.00
IUUC-Aca-004533	Anolis carolinensis	76.30	7.00e-132	462.00
IUUC-Bta-012641	Bos taurus	94.79	2.00e-167	580.00
IUUC-Bol-016316	Brassica oleracea	28.92	6.00e-16	78.60
IUUC-Bra-018037	Brassica rapa	27.40	3.00e-13	69.70
IUUC-Cja-019626	Callithrix jacchus	78.50	8.00e-133	466.00
IUUC-Cfa-020702	Canis familiaris	91.86	6.00e-163	565.00
IUUC-Cpo-022147	Cavia porcellus	92.51	1.00e-162	565.00
IUUC-Csa-023473	Chlorocebus sabaeus	93.49	3.00e-165	573.00
IUUC-Cho-024298	Choloepus hoffmanni	88.51	1.00e-137	481.00
IUUC-Dre-028099	Danio rerio	64.57	2.00e-86	311.00
IUUC-Dno-029122	Dasypus novemcinctus	86.69	4.00e-150	523.00
IUUC-Dor-030669	Dipodomys ordii	94.42	3.00e-127	446.00
IUUC-Ete-033141	Echinops telfairi	79.15	7.00e-125	439.00
IUUC-Eca-034360	Equus caballus	94.14	6.00e-166	576.00
IUUC-Eeu-034538	Erinaceus europaeus	71.83	6.00e-79	286.00
IUUC-Fca-036055	Felis catus	90.55	7.00e-159	552.00
IUUC-Fal-037339	Ficedula albicollis	80.92	9.00e-133	465.00
IUUC-Gmo-038780	Gadus morhua	58.80	9.00e-82	296.00
IUUC-Gga-040256	Gallus gallus	80.00	2.00e-132	464.00
IUUC-Gac-042127	Gasterosteus aculeatus	61.69	7.00e-89	320.00
IUUC-Ggo-044867	Gorilla gorilla	93.81	1.00e-165	575.00
IUUC-Hsa-046928	Homo sapiens	93.49	3.00e-165	573.00
IUUC-Hvu-047484	Hordeum vulgare	30.73	1.00e-17	84.30
IUUC-Itr-048250	Ictidomys tridecemlineatus	94.82	2.00e-103	367.00
IUUC-Lch-050168	Latimeria chalumnae	72.82	7.00e-125	439.00
IUUC-Lpe-051649	Leersia perrieri	29.56	3.00e-17	84.00
IUUC-Loc-052150	Lepisosteus oculatus	61.35	2.00e-90	325.00
IUUC-Laf-053967	Loxodonta africana	93.16	1.00e-163	568.00
IUUC-Mcc-055898	Macaca mulatta	93.49	3.00e-165	573.00
IUUC-Meu-056628	Macropus eugenii	96.10	1.00e-42	166.00
IUUC-Mtr-057989	Medicago truncatula	26.82	3.00e-19	88.60
IUUC-Mga-059820	Meleagris gallopavo	78.95	1.00e-130	458.00
IUUC-Mmr-060680	Microcebus murinus	92.51	8.00e-162	562.00
IUUC-Mdo-062839	Monodelphis domestica	84.74	1.00e-148	518.00
IUUC-Mmu-063339	Mus musculus	85.34	2.00e-140	491.00
IUUC-Mac-065414	Musa acuminata	28.91	2.00e-19	89.70
IUUC-Mpu-065973	Mustela putorius furo	90.23	7.00e-159	552.00
IUUC-Mlu-067112	Myotis lucifugus	92.18	6.00e-158	549.00
IUUC-Nle-069795	Nomascus leucogenys	93.16	3.00e-165	573.00
IUUC-Opr-070390	Ochotona princeps	86.64	2.00e-146	511.00
IUUC-Ont-072329	Oreochromis niloticus	60.87	1.00e-88	319.00
IUUC-Oan-072980	Ornithorhynchus anatinus	83.33	4.00e-133	466.00
IUUC-Ocu-073845	Oryctolagus cuniculus	92.18	1.00e-162	565.00
IUUC-Ola-086872	Oryzias latipes	61.09	2.00e-80	291.00
IUUC-Oga-088954	Otolemur garnettii	92.18	3.00e-162	563.00
IUUC-Oar-089879	Ovis aries	95.44	2.00e-168	583.00
IUUC-Ptr-090685	Pan troglodytes	93.49	3.00e-165	573.00
IUUC-Pan-092086	Papio anubis	93.16	5.00e-165	573.00
IUUC-Psi-093481	Pelodiscus sinensis	81.43	5.00e-135	473.00
IUUC-Pfo-096065	Poecilia formosa	65.35	1.00e-87	315.00
IUUC-Pab-098031	Pongo abelii	93.16	4.00e-164	569.00
IUUC-Pop-099816	Populus trichocarpa	27.19	3.00e-16	79.30
IUUC-Pca-100936	Procavia capensis	91.21	1.00e-159	555.00
IUUC-Pva-102864	Pteropus vampyrus	82.08	4.00e-140	490.00
IUUC-Rno-105503	Rattus norvegicus	85.34	4.00e-140	489.00
IUUC-Sha-107425	Sarcophilus harrisii	84.74	2.00e-148	517.00
IUUC-Stu-112736	Solanum tuberosum	27.23	4.00e-19	87.80
IUUC-Tgu-117226	Taeniopygia guttata	79.86	1.00e-132	465.00
IUUC-Tru-118362	Takifugu rubripes	65.41	9.00e-89	319.00
IUUC-Tsy-119255	Tarsius syrichta	93.81	1.00e-165	574.00
IUUC-Tni-120140	Tetraodon nigroviridis	62.45	2.00e-84	305.00
IUUC-Tae-124420	Triticum aestivum	32.32	1.00e-18	87.40
IUUC-Tbe-127306	Tupaia belangeri	94.14	7.00e-166	575.00
IUUC-Ttr-128923	Tursiops truncatus	94.14	2.00e-158	550.00
IUUC-Vpa-130148	Vicugna pacos	94.14	2.00e-164	571.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence