iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021356

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02050726

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000026884.1	ENSCPOT00000024520.1	ENSCPOP00000014490.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-44	147.2	227	266
UBD/Beta-Prp	4.90e-75	252.4	9	300

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 227  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 266
           8***********777*****************99999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    +++++ ++tgs d+ +kvw+++++ l   +sl+gh+ +v +v++s++ +i +++s D++i++wdl++gk++ 
   Q: 9    EQAHDDAIWSVAWgtnkKENSETVVTGSLDDLVKVWKWSDERLdlQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIK 97
           567788888899998888999********************99999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 98   SIDAAPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 185
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ ++++++t+  h+++
   Q: 186  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 273
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 274  VWGVKY-NGNGSKIVSVGDDQEIHIYDC 300
           ******.999****************98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QYSILFKQEQ AHDDAIWSVA WGTNKKENSE TVVTGSLDDL VKVWKWSDER LDLQWSLEGH 60
QLGVVSVDIS HTLPIAASSS LDAHIRLWDL ENGKQIKSID AAPVDAWTLA FSPDSQYLAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTACAGTA TTCTCTTCAA ACAAGAACAA GGTAAGGAAC CTGCCTGTTC AAGCAGGTCC 60
ATGCCTCTGT GTGAAAAGCT TGTTCATCTT TGAGCACCTG GTTCTCACGC CAGCCCAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.23	4.00e-48	184.00
IUUC-Aml-002245	Ailuropoda melanoleuca	99.01	1.00e-166	578.00
IUUC-Atr-003142	Amborella trichopoda	51.55	2.00e-38	152.00
IUUC-Apl-003179	Anas platyrhynchos	90.73	5.00e-155	540.00
IUUC-Aca-004880	Anolis carolinensis	88.41	5.00e-156	543.00
IUUC-Aly-005956	Arabidopsis lyrata	37.50	2.00e-55	209.00
IUUC-Ath-007230	Arabidopsis thaliana	37.18	3.00e-51	195.00
IUUC-Acl-008297	Aspergillus clavatus	28.52	1.00e-24	107.00
IUUC-Ang-009702	Aspergillus niger	29.87	1.00e-29	123.00
IUUC-Ame-011511	Astyanax mexicanus	84.54	3.00e-148	517.00
IUUC-Bgr-012189	Blumeria graminis	31.05	1.00e-28	120.00
IUUC-Bta-012936	Bos taurus	98.68	1.00e-165	575.00
IUUC-Bdi-015020	Brachypodium distachyon	37.59	2.00e-47	182.00
IUUC-Bol-016345	Brassica oleracea	38.78	9.00e-57	213.00
IUUC-Bra-017323	Brassica rapa	38.78	8.00e-57	213.00
IUUC-Cja-019961	Callithrix jacchus	99.01	6.00e-166	576.00
IUUC-Cfa-020862	Canis familiaris	98.34	2.00e-165	574.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	42.76	5.00e-58	217.00
IUUC-Csa-024067	Chlorocebus sabaeus	98.68	3.00e-165	573.00
IUUC-Cho-024421	Choloepus hoffmanni	83.84	7.00e-83	299.00
IUUC-Cin-025261	Ciona intestinalis	64.90	4.00e-115	407.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.25	2.00e-28	119.00
IUUC-Cne-026846	Cryptococcus neoformans	28.71	3.00e-24	105.00
IUUC-Dre-027706	Danio rerio	66.23	3.00e-109	387.00
IUUC-Dno-029084	Dasypus novemcinctus	98.68	8.00e-165	572.00
IUUC-Dor-030353	Dipodomys ordii	86.26	4.00e-122	430.00
IUUC-Dse-031348	Dothistroma septosporum	31.03	5.00e-26	111.00
IUUC-Dme-031836	Drosophila melanogaster	52.31	2.00e-87	315.00
IUUC-Ete-032261	Echinops telfairi	95.70	4.00e-159	553.00
IUUC-Eca-034231	Equus caballus	91.06	3.00e-150	524.00
IUUC-Eeu-034828	Erinaceus europaeus	97.25	6.00e-156	542.00
IUUC-Fca-036569	Felis catus	99.01	3.00e-166	577.00
IUUC-Fal-037469	Ficedula albicollis	92.72	7.00e-159	552.00
IUUC-Fox-038047	Fusarium oxysporum	32.99	7.00e-29	120.00
IUUC-Gmo-039579	Gadus morhua	84.44	3.00e-145	507.00
IUUC-Gga-040808	Gallus gallus	93.15	2.00e-153	535.00
IUUC-Gac-042100	Gasterosteus aculeatus	84.77	1.00e-146	511.00
IUUC-Gma-044408	Glycine max	41.35	1.00e-59	223.00
IUUC-Ggo-045227	Gorilla gorilla	99.01	6.00e-166	576.00
IUUC-Hsa-045839	Homo sapiens	99.01	6.00e-166	576.00
IUUC-Hvu-047591	Hordeum vulgare	38.29	3.00e-50	191.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	99.34	2.00e-166	578.00
IUUC-Lch-049549	Latimeria chalumnae	84.11	4.00e-146	510.00
IUUC-Lpe-050746	Leersia perrieri	38.59	3.00e-48	185.00
IUUC-Loc-052540	Lepisosteus oculatus	87.42	4.00e-148	516.00
IUUC-Lma-052992	Leptosphaeria maculans	28.33	1.00e-27	116.00
IUUC-Laf-053907	Loxodonta africana	99.34	2.00e-166	578.00
IUUC-Mcc-055828	Macaca mulatta	92.55	8.00e-162	562.00
IUUC-Meu-056075	Macropus eugenii	94.49	2.00e-134	471.00
IUUC-Mtr-057728	Medicago truncatula	40.71	1.00e-56	213.00
IUUC-Mga-059872	Meleagris gallopavo	93.05	1.00e-159	555.00
IUUC-Mvi-060564	Microbotryum violaceum	32.11	1.00e-29	123.00
IUUC-Mmr-060985	Microcebus murinus	98.97	1.00e-159	555.00
IUUC-Mdo-062758	Monodelphis domestica	91.03	1.00e-157	548.00
IUUC-Mmu-063580	Mus musculus	97.02	8.00e-164	569.00
IUUC-Mac-064880	Musa acuminata	40.19	5.00e-58	217.00
IUUC-Mpu-066577	Mustela putorius furo	98.34	5.00e-165	573.00
IUUC-Nle-069573	Nomascus leucogenys	99.01	6.00e-166	576.00
IUUC-Opr-070216	Ochotona princeps	97.67	2.00e-164	571.00
IUUC-Ont-071981	Oreochromis niloticus	86.09	3.00e-149	520.00
IUUC-Oan-073223	Ornithorhynchus anatinus	93.43	4.00e-107	379.00
IUUC-Ocu-074199	Oryctolagus cuniculus	84.77	1.00e-137	482.00
IUUC-Oba-075255	Oryza barthii	40.00	1.00e-41	163.00
IUUC-Obr-076168	Oryza brachyantha	47.20	1.00e-35	143.00
IUUC-Ogl-077777	Oryza glaberrima	38.39	6.00e-49	187.00
IUUC-Ogu-078780	Oryza glumaepatula	38.39	6.00e-49	187.00
IUUC-Oin-079228	Oryza indica	38.39	1.00e-51	196.00
IUUC-Olo-080617	Oryza longistaminata	45.77	2.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.39	3.00e-48	185.00
IUUC-Oni-082997	Oryza nivara	38.39	1.00e-51	196.00
IUUC-Opu-083931	Oryza punctata	38.71	5.00e-49	187.00
IUUC-Oru-084645	Oryza rufipogon	38.39	6.00e-49	187.00
IUUC-Osa-085842	Oryza sativa	38.39	1.00e-51	196.00
IUUC-Ola-086696	Oryzias latipes	85.43	5.00e-145	506.00
IUUC-Olu-087643	Ostreococcus lucimarinus	40.38	3.00e-42	164.00
IUUC-Oga-088272	Otolemur garnettii	97.34	2.00e-162	564.00
IUUC-Oar-089416	Ovis aries	98.68	1.00e-165	575.00
IUUC-Ptr-090944	Pan troglodytes	99.01	6.00e-166	576.00
IUUC-Pan-091861	Papio anubis	99.01	6.00e-166	576.00
IUUC-Psi-093750	Pelodiscus sinensis	94.04	3.00e-160	557.00
IUUC-Pma-094608	Petromyzon marinus	79.80	6.00e-134	469.00
IUUC-Pno-094832	Phaeosphaeria nodorum	32.59	2.00e-26	112.00
IUUC-Ppa-095737	Physcomitrella patens	40.06	2.00e-56	212.00
IUUC-Pfo-096479	Poecilia formosa	86.75	2.00e-143	501.00
IUUC-Pab-098179	Pongo abelii	99.01	6.00e-166	576.00
IUUC-Pop-099532	Populus trichocarpa	40.91	2.00e-56	212.00
IUUC-Pca-100664	Procavia capensis	76.19	1.00e-103	369.00
IUUC-Ppe-102056	Prunus persica	40.26	2.00e-58	218.00
IUUC-Pva-102859	Pteropus vampyrus	98.68	3.00e-165	573.00
IUUC-Pte-104236	Pyrenophora teres	35.56	2.00e-25	109.00
IUUC-Rno-105826	Rattus norvegicus	96.69	5.00e-163	566.00
IUUC-Sha-106660	Sarcophilus harrisii	92.03	2.00e-152	531.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.22	9.00e-36	143.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.37	7.00e-35	140.00
IUUC-Smo-109234	Selaginella moellendorffii	42.81	3.00e-61	228.00
IUUC-Sit-110048	Setaria italica	36.86	7.00e-41	160.00
IUUC-Sly-111618	Solanum lycopersicum	38.78	2.00e-52	199.00
IUUC-Stu-112543	Solanum tuberosum	39.10	1.00e-55	210.00
IUUC-Sar-113743	Sorex araneus	78.15	6.00e-128	449.00
IUUC-Sbi-114309	Sorghum bicolor	38.57	4.00e-42	164.00
IUUC-Ssc-115560	Sus scrofa	93.05	2.00e-152	531.00
IUUC-Tgu-117300	Taeniopygia guttata	93.05	2.00e-159	554.00
IUUC-Tru-117933	Takifugu rubripes	85.43	2.00e-148	518.00
IUUC-Tsy-119574	Tarsius syrichta	88.41	2.00e-142	498.00
IUUC-Tni-120191	Tetraodon nigroviridis	86.92	2.00e-112	397.00
IUUC-Tca-120983	Theobroma cacao	39.81	4.00e-57	214.00
IUUC-Tae-124056	Triticum aestivum	36.48	3.00e-50	192.00
IUUC-Tur-126711	Triticum urartu	36.36	4.00e-49	188.00
IUUC-Tme-127066	Tuber melanosporum	33.46	2.00e-33	136.00
IUUC-Tbe-127802	Tupaia belangeri	99.01	3.00e-166	577.00
IUUC-Ttr-128861	Tursiops truncatus	97.09	1.00e-53	202.00
IUUC-Vda-129720	Verticillium dahliae	29.02	6.00e-23	101.00
IUUC-Vpa-130618	Vicugna pacos	98.71	7.00e-133	466.00
IUUC-Vvi-130981	Vitis vinifera	40.38	6.00e-56	210.00
IUUC-Xtr-132460	Xenopus tropicalis	86.75	2.00e-145	508.00
IUUC-Xma-134154	Xiphophorus maculatus	86.75	2.00e-143	501.00
IUUC-Yli-134554	Yarrowia lipolytica	28.52	4.00e-20	92.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence