iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093750

Ensembl Protein ID

ENSPSIP00000009773.1

UniProt Accession

K7FP13; K7FP13_PELSI

Genbank Protein ID

ENSPSIP00000009773

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01045241

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000008819.1	ENSPSIT00000009821.1	ENSPSIP00000009773.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-45	150.7	252	290
UBD/Beta-Prp	2.00e-75	253.7	34	325

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v  +af +d t++vs+s D+++kvWD  t ++++
   Q: 252  GHGSWVLNVAFcPDdTHFVSSSSDKSVKVWDAVTRTCVH 290
           8***********777****************99999887 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++     ++++ +++gs d+ +kvw++t++kl   ++l+gh+ +v +v++s++g i +++s D++i++wdl+tgk++ 
   Q: 34   EQAHDDAIWSVAWgknkRDGSETVISGSLDDLVKVWKWTDEKLdlQWTLEGHQLGVVSVDISHTGTIAASSSLDAHIRLWDLETGKQIK 122
           5677777888999887777899********************9999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   +++sl+fsp++++l++Gsh+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 123  SIDAGPVDAWSLAFSPDSQYLATGSHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 210
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd  ++++++t+  h+++
   Q: 211  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHGSWVLNVAFCPDDTHFVSSSSDKSVKVWDAVTRTCVHTFFDHQDQ 298
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 299  VWGVKY-NGNGSKIVSVGDDQEIHIYDC 325
           ******.999****************98 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MQFHSHWSVC RIFLCIFSLY KEMTTQYSIL FKQEQAHDDA IWSVAWGKNK RDGSETVISG 60
SLDDLVKVWK WTDEKLDLQW TLEGHQLGVV SVDISHTGTI AASSSLDAHI RLWDLETGKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN GGAGAGAAGA GGGAGCAAAG GAGGGGGTGG TTCAAAACGG 60
CAGCGTGGTA TGGAGCCTGC TTGGGACTCC CCCGCTAAGC CCAGGCTCCA TGCAGCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

pss:102453886

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	33.43	3.00e-46	178.00
IUUC-Aml-002245	Ailuropoda melanoleuca	93.44	3.00e-160	556.00
IUUC-Atr-003142	Amborella trichopoda	50.93	1.00e-37	148.00
IUUC-Apl-003179	Anas platyrhynchos	94.75	3.00e-162	563.00
IUUC-Aca-004880	Anolis carolinensis	91.48	4.00e-162	563.00
IUUC-Aly-005956	Arabidopsis lyrata	38.46	1.00e-57	216.00
IUUC-Ath-007230	Arabidopsis thaliana	38.14	4.00e-52	197.00
IUUC-Acl-008297	Aspergillus clavatus	29.24	9.00e-26	110.00
IUUC-Ame-011511	Astyanax mexicanus	86.64	2.00e-153	534.00
IUUC-Bgr-012189	Blumeria graminis	30.99	6.00e-31	127.00
IUUC-Bta-012936	Bos taurus	94.43	2.00e-160	558.00
IUUC-Bdi-015020	Brachypodium distachyon	37.24	4.00e-46	178.00
IUUC-Bol-015927	Brassica oleracea	38.78	3.00e-58	218.00
IUUC-Bra-017323	Brassica rapa	38.46	8.00e-58	216.00
IUUC-Cja-019961	Callithrix jacchus	93.77	2.00e-159	554.00
IUUC-Cfa-020862	Canis familiaris	93.11	5.00e-159	553.00
IUUC-Cpo-021356	Cavia porcellus	94.04	2.00e-158	551.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.78	2.00e-58	218.00
IUUC-Csa-024067	Chlorocebus sabaeus	93.44	1.00e-158	551.00
IUUC-Cho-024421	Choloepus hoffmanni	81.31	2.00e-80	291.00
IUUC-Cin-025261	Ciona intestinalis	65.25	9.00e-119	419.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.30	3.00e-29	122.00
IUUC-Cne-026846	Cryptococcus neoformans	27.92	1.00e-21	97.10
IUUC-Dre-027706	Danio rerio	67.21	2.00e-113	401.00
IUUC-Dno-029084	Dasypus novemcinctus	93.49	1.00e-158	551.00
IUUC-Dor-030353	Dipodomys ordii	78.99	1.00e-116	412.00
IUUC-Dse-031348	Dothistroma septosporum	31.22	3.00e-26	112.00
IUUC-Dme-031836	Drosophila melanogaster	51.08	4.00e-87	314.00
IUUC-Ete-032261	Echinops telfairi	90.82	3.00e-153	533.00
IUUC-Eca-034231	Equus caballus	86.23	3.00e-144	503.00
IUUC-Eeu-034828	Erinaceus europaeus	92.10	3.00e-148	516.00
IUUC-Fca-036569	Felis catus	93.77	1.00e-159	555.00
IUUC-Fal-037469	Ficedula albicollis	97.05	5.00e-166	576.00
IUUC-Fox-038047	Fusarium oxysporum	34.12	2.00e-30	125.00
IUUC-Gmo-039579	Gadus morhua	84.92	3.00e-148	517.00
IUUC-Gga-040808	Gallus gallus	97.26	6.00e-159	552.00
IUUC-Gac-042100	Gasterosteus aculeatus	87.54	4.00e-152	530.00
IUUC-Gma-044408	Glycine max	41.35	4.00e-60	224.00
IUUC-Ggo-045227	Gorilla gorilla	93.77	2.00e-159	554.00
IUUC-Hsa-045839	Homo sapiens	93.77	2.00e-159	554.00
IUUC-Hvu-047591	Hordeum vulgare	37.66	4.00e-48	184.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	94.10	3.00e-160	556.00
IUUC-Lch-049549	Latimeria chalumnae	86.23	3.00e-151	527.00
IUUC-Lpe-050746	Leersia perrieri	38.26	9.00e-47	180.00
IUUC-Loc-052540	Lepisosteus oculatus	88.85	4.00e-154	536.00
IUUC-Lma-052992	Leptosphaeria maculans	29.14	2.00e-28	119.00
IUUC-Laf-053907	Loxodonta africana	94.10	3.00e-160	556.00
IUUC-Mcc-055828	Macaca mulatta	87.69	2.00e-155	540.00
IUUC-Meu-056075	Macropus eugenii	95.28	8.00e-135	472.00
IUUC-Mor-056971	Magnaporthe oryzae	27.30	9.00e-25	107.00
IUUC-Mtr-057728	Medicago truncatula	40.71	3.00e-57	214.00
IUUC-Mga-059872	Meleagris gallopavo	97.05	2.00e-166	577.00
IUUC-Mvi-060564	Microbotryum violaceum	31.54	6.00e-30	124.00
IUUC-Mmr-060985	Microcebus murinus	89.31	4.00e-154	536.00
IUUC-Mdo-062758	Monodelphis domestica	91.45	4.00e-159	553.00
IUUC-Mmu-063580	Mus musculus	91.80	2.00e-157	547.00
IUUC-Mac-064880	Musa acuminata	40.51	3.00e-58	218.00
IUUC-Mpu-066577	Mustela putorius furo	93.11	7.00e-159	552.00
IUUC-Nle-069573	Nomascus leucogenys	93.77	2.00e-159	554.00
IUUC-Opr-070216	Ochotona princeps	92.69	1.00e-156	545.00
IUUC-Ont-071981	Oreochromis niloticus	87.54	9.00e-154	535.00
IUUC-Oan-073223	Ornithorhynchus anatinus	94.95	2.00e-108	384.00
IUUC-Ocu-074199	Oryctolagus cuniculus	80.00	1.00e-130	458.00
IUUC-Oba-075255	Oryza barthii	40.00	1.00e-40	159.00
IUUC-Obr-076168	Oryza brachyantha	46.58	2.00e-34	139.00
IUUC-Ogl-077777	Oryza glaberrima	38.26	2.00e-47	182.00
IUUC-Ogu-078780	Oryza glumaepatula	38.26	2.00e-47	182.00
IUUC-Oin-079228	Oryza indica	38.26	4.00e-50	191.00
IUUC-Olo-080617	Oryza longistaminata	45.07	3.00e-28	116.00
IUUC-Ome-081421	Oryza meridionalis	38.26	1.00e-46	179.00
IUUC-Oni-082997	Oryza nivara	38.26	4.00e-50	191.00
IUUC-Opu-083931	Oryza punctata	38.39	2.00e-47	182.00
IUUC-Oru-084645	Oryza rufipogon	38.26	2.00e-47	182.00
IUUC-Osa-085842	Oryza sativa	38.26	4.00e-50	191.00
IUUC-Ola-086696	Oryzias latipes	87.54	8.00e-151	525.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	2.00e-41	161.00
IUUC-Oga-088272	Otolemur garnettii	93.42	4.00e-158	550.00
IUUC-Oar-089416	Ovis aries	94.43	2.00e-160	558.00
IUUC-Ptr-090944	Pan troglodytes	93.77	2.00e-159	554.00
IUUC-Pan-091861	Papio anubis	93.77	2.00e-159	554.00
IUUC-Pma-094608	Petromyzon marinus	81.94	2.00e-138	484.00
IUUC-Pno-094832	Phaeosphaeria nodorum	28.67	2.00e-26	112.00
IUUC-Ppa-095737	Physcomitrella patens	40.38	2.00e-56	212.00
IUUC-Pfo-096479	Poecilia formosa	89.18	8.00e-148	515.00
IUUC-Pab-098179	Pongo abelii	93.77	2.00e-159	554.00
IUUC-Pop-099532	Populus trichocarpa	40.56	4.00e-56	211.00
IUUC-Pca-100664	Procavia capensis	73.19	5.00e-100	356.00
IUUC-Ppe-102056	Prunus persica	40.26	9.00e-58	216.00
IUUC-Pva-102859	Pteropus vampyrus	93.44	8.00e-159	552.00
IUUC-Pte-104236	Pyrenophora teres	30.41	5.00e-26	111.00
IUUC-Rno-105826	Rattus norvegicus	91.48	9.00e-157	545.00
IUUC-Sha-106660	Sarcophilus harrisii	92.36	4.00e-151	526.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.55	4.00e-36	144.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.72	2.00e-35	142.00
IUUC-Smo-109234	Selaginella moellendorffii	43.14	5.00e-62	230.00
IUUC-Sit-110048	Setaria italica	36.77	2.00e-39	155.00
IUUC-Sly-111618	Solanum lycopersicum	38.14	6.00e-52	197.00
IUUC-Stu-112543	Solanum tuberosum	38.14	5.00e-55	207.00
IUUC-Sar-113743	Sorex araneus	74.75	2.00e-124	437.00
IUUC-Sbi-114309	Sorghum bicolor	38.83	4.00e-41	161.00
IUUC-Ssc-115560	Sus scrofa	89.18	9.00e-149	518.00
IUUC-Tgu-117300	Taeniopygia guttata	97.38	1.00e-166	578.00
IUUC-Tru-117933	Takifugu rubripes	88.20	4.00e-154	536.00
IUUC-Tsy-119574	Tarsius syrichta	83.28	5.00e-136	476.00
IUUC-Tni-120191	Tetraodon nigroviridis	89.03	9.00e-115	405.00
IUUC-Tca-120983	Theobroma cacao	40.45	2.00e-58	219.00
IUUC-Tae-124056	Triticum aestivum	35.85	2.00e-48	185.00
IUUC-Tur-126711	Triticum urartu	35.74	3.00e-47	182.00
IUUC-Tme-127066	Tuber melanosporum	34.20	8.00e-35	140.00
IUUC-Tbe-127802	Tupaia belangeri	93.77	1.00e-159	555.00
IUUC-Ttr-128861	Tursiops truncatus	90.48	7.00e-52	196.00
IUUC-Vda-129720	Verticillium dahliae	29.27	1.00e-23	103.00
IUUC-Vpa-130618	Vicugna pacos	89.88	5.00e-128	449.00
IUUC-Vvi-130981	Vitis vinifera	40.38	2.00e-56	212.00
IUUC-Xtr-132460	Xenopus tropicalis	89.18	4.00e-152	530.00
IUUC-Xma-134154	Xiphophorus maculatus	89.18	4.00e-148	516.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence