iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000171804.10	ENST00000447313.6	ENSP00000405012.2
ENSG00000171804.10	ENST00000303868.5	ENSP00000368025.3

Annotation

Cancer Mutation
ICGC	COSMIC	CGAP	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	HPM
DNA & RNA Element
UTRdb	CircNet	microRNA	TRANSFAC
TargetScan	miRcode	RAID2
Post-translational Modifications (PTMs)
CPLM	BioGRID
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-09	39.4	605	635

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H + +t+++   +  l+v+Gs Dg++++WD+
   Q: 605  HLCAITSFDVcLSlSLFVTGSADGSVRIWDF 635
           7777888655534469**************5 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MSSPRLIPLW KDLKLLLNDT INKSKQPSED PKNCLIVLSD RSQVLFKESR YPQNMPCVCY 60
YFSDAHFFAS LSWVTSNTKE IQAVAWMKSK TEDMVEKRTF SMTERLPPIQ SMVHAGSFHI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCGCGTTC AGACCCCTGG CCTCGGGAAG TCCGCCGGCT GCGGGGTTGG GGGCCAACCG 60
TTCTGTGGGC GGAGTCCTCT CGCAACATCC GCCAGGTAGC TTCTTAGTTG CTGCCCCTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001736	Ailuropoda melanoleuca	68.31	0.00e+00	2415.00
IUUC-Aca-004571	Anolis carolinensis	35.10	8.00e-162	564.00
IUUC-Bta-012814	Bos taurus	62.53	0.00e+00	2262.00
IUUC-Cja-018777	Callithrix jacchus	83.99	0.00e+00	3196.00
IUUC-Cfa-020777	Canis familiaris	63.03	0.00e+00	2197.00
IUUC-Cpo-022298	Cavia porcellus	63.43	0.00e+00	1964.00
IUUC-Csa-023651	Chlorocebus sabaeus	91.95	0.00e+00	3340.00
IUUC-Dno-030011	Dasypus novemcinctus	66.36	0.00e+00	2499.00
IUUC-Ete-033165	Echinops telfairi	70.66	0.00e+00	1775.00
IUUC-Eca-034087	Equus caballus	59.74	0.00e+00	1120.00
IUUC-Eeu-034728	Erinaceus europaeus	70.74	0.00e+00	1524.00
IUUC-Fca-035624	Felis catus	69.56	0.00e+00	2115.00
IUUC-Ggo-044880	Gorilla gorilla	97.85	0.00e+00	3550.00
IUUC-Itr-048442	Ictidomys tridecemlineatus	63.77	0.00e+00	2289.00
IUUC-Laf-053770	Loxodonta africana	79.77	0.00e+00	1774.00
IUUC-Mcc-054980	Macaca mulatta	91.85	0.00e+00	3462.00
IUUC-Meu-056794	Macropus eugenii	52.65	0.00e+00	1030.00
IUUC-Mmr-061632	Microcebus murinus	65.76	0.00e+00	2473.00
IUUC-Mdo-061880	Monodelphis domestica	43.33	2.00e-08	55.50
IUUC-Mpu-066223	Mustela putorius furo	66.94	0.00e+00	2434.00
IUUC-Mlu-068087	Myotis lucifugus	66.68	0.00e+00	2315.00
IUUC-Nle-069946	Nomascus leucogenys	94.56	0.00e+00	3484.00
IUUC-Opr-070516	Ochotona princeps	74.02	0.00e+00	1620.00
IUUC-Oan-072735	Ornithorhynchus anatinus	46.39	0.00e+00	1041.00
IUUC-Ocu-074293	Oryctolagus cuniculus	66.94	0.00e+00	2146.00
IUUC-Oga-088902	Otolemur garnettii	65.45	0.00e+00	1831.00
IUUC-Oar-089996	Ovis aries	63.06	0.00e+00	2306.00
IUUC-Ptr-091342	Pan troglodytes	92.96	0.00e+00	3565.00
IUUC-Pan-091863	Papio anubis	91.77	0.00e+00	3405.00
IUUC-Pab-098183	Pongo abelii	94.07	0.00e+00	2384.00
IUUC-Pca-100733	Procavia capensis	75.56	0.00e+00	932.00
IUUC-Pva-102765	Pteropus vampyrus	83.86	0.00e+00	756.00
IUUC-Rno-104850	Rattus norvegicus	48.58	0.00e+00	957.00
IUUC-Sha-106915	Sarcophilus harrisii	39.45	6.00e-174	606.00
IUUC-Sar-113716	Sorex araneus	65.89	0.00e+00	696.00
IUUC-Ssc-115664	Sus scrofa	78.98	0.00e+00	1914.00
IUUC-Tsy-119602	Tarsius syrichta	78.35	0.00e+00	1311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence